(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Derogate
Definition:
(v. t.) To annul in part; to repeal partly; to restrict; to limit the action of; -- said of a law.
(v. t.) To lessen; to detract from; to disparage; to depreciate; -- said of a person or thing.
(v. i.) To take away; to detract; to withdraw; -- usually with from.
(v. i.) To act beneath one-s rank, place, birth, or character; to degenerate.
(n.) Diminished in value; dishonored; degraded.
Example Sentences:
(1) The observed increase in self-derogation over a 1-year period in persons with initially positive self-attitudes is discussed with regard to the literature on developmental disturbances in self-image; differential volunerability to self-devaluing experiences; and the relationship between change in, and level of, self-acceptance.
(2) Results indicate that health care presented within the context of not having a choice is derogated and that choice and patient mix combine to influence intentions to seek care.
(3) Results indicated an effect of sex identification; the male blunderer was derogated most by male subjects (n = 34) and the female most by female subjects (n = 34).
(4) However, whether or not suicidal behaviors are related to self-derogating feelings in the more remote past can be seen as a function of a sex-social-class-mode of suicidal response interaction.
(5) Inspectors found that senior staff at Durham Free School had allowed a culture to develop where it was acceptable for racist words and sexually derogative and homophobic terms to be used.
(6) Detaining non-suspects for up to seven days, virtually incommunicado and without effective review at the time, removing the right to silence on penalty of imprisonment, and criminalising any disclosure of detention, is excessive and disproportionate in view of existing powers, the level of terrorist threat, and the absence of any declared public emergency justifying derogation from protected human rights.
(7) Some derogations could attenuate the severity of these dispositions--as jurisprudence had taken progresses of Epileptology and therapeutics into consideration.
(8) The duty of care owed by the commonwealth to asylum seekers and refugees is non-derogable – it cannot be suspended or transferred.
(9) Self-derogators were judged to be submissive, elicited dominating reactions, and selected more topics with negative content.
(10) A particularly interesting interpretation of this phenomenon, consistent with a large body of clinical and experimental literature, ascribes it to self-derogation processes in low-PA persons and self-enhancement processes in high-PA persons.
(11) But Caoilfhionn Gallagher, representing the media with Mike Dodd, legal editor of the Press Association, said not knowing the names would be “a major derogation from the open justice principle” – and that the public had a right to know who, and what, was going on in public courts.
(12) We predicted that authoritarian actors would engage in defensive attribution, and authoritarian observers would derogate the other, to a greater extent than egalitarian perceivers.
(13) The commission should expand the EU-wide ban to cover all uses of neonicotinoids on all crops, and end the self-service approach to derogations.
(14) 10c derogation intent When the EU adopted the climate and energy package in December 2008, the 10c derogation was included as an exception to the rule that from 2013 onwards, all allowances for power companies should be auctioned rather than granted for free.
(15) Many Tories were demanding she went for a temporary derogation of human rights laws.
(16) Attitudes toward victims of AIDS were conceptualized as serving three possible functions: a value-expressive function (e.g., stigmatization), an ego-defensive function (e.g., homosexual prejudice), or a knowledge function (e.g., victim derogation).
(17) The report adds: "As they incorporate derogations from the principle of open justice, superinjunctions and anonymised injunctions can only be granted when they are strictly necessary.
(18) Experiments 1 and 2 showed that self-derogations connote submissiveness but are generally judged to be neutral in affiliation.
(19) The European parliament’s industry committee last month approved a rule change allowing Greece to join the scheme, the ‘10c derogation’ of the emissions trading system (ETS).
(20) Article 15 of the human rights convention allows a state to withdraw temporarily or derogate in legal terms from some of its rights in times of national emergency which threaten the life of the nation, to allow the use of measures that have to be "strictly required".