(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Devolve
Definition:
(v. t.) To roll onward or downward; to pass on.
(v. t.) To transfer from one person to another; to deliver over; to hand down; -- generally with upon, sometimes with to or into.
(v. i.) To pass by transmission or succession; to be handed over or down; -- generally with on or upon, sometimes with to or into; as, after the general fell, the command devolved upon (or on) the next officer in rank.
Example Sentences:
(1) Photograph: Gareth Phillips for the Guardian Because health is devolved, the Welsh government can do things differently from England.
(2) This isn’t a devolved matter, this is about when they come to our shores here, UK taxpayers and their ability to use UK services,” Creasy said.
(3) We have already had the failure of House of Lords reform, the failure to change constituencies and the imbalance of MPs between England and the devolved assemblies.
(4) I want Monday’s meeting to be the start of a new grown-up relationship between the devolved administrations and the UK government – one in which we all work together to forge the future for everyone in the United Kingdom,” she said.
(5) Nowadays, many of the core welfare state functions have been devolved to the Scottish parliament.
(6) He implied that if Salmond lost the referendum, that would then expose different questions about the organisation and survival of the UK, where power has been devolved in, he said, an incoherent way.
(7) That included "a higher minimum wage; stopping the abuse of zero-hours contracts; skills and careers for all our young people; banks working for businesses again; energy bills frozen; 200,000 homes built a year by 2020; power devolved; the bedroom tax abolished; and our National Health Service restored".
(8) Some, including the Dutch and Polish government, are more interested in devolving power back to the member states.
(9) The 32 dead souls ringing the Dr Strangelove war room of the NFL ownership meeting interrupt their Randroid tongue-bathing only to squeal like scalded truffle pigs at the thought of any power devolving to the actual people whose ability, knowledge and gameplay make the NFL worth watching in the first place.
(10) "In the meantime, we urge the Westminster government to follow the Scottish example, embrace a Plan MacB approach for the UK economy and work with the three devolved administrations through a jobs summit to agree an immediate programme of employment creation."
(11) But if UK solidarity – and the rhetoric of one nation – is to mean something for every person in every corner of a devolved UK, much is to be said for caution over cutting one of the strongest ties that bind.
(12) I am very clear that I want to ensure we get the best possible deal for the United Kingdom that works for everyone across the United Kingdom and all parts of the UK when we enter these negotiation,” said the prime minister in Wales, at the start of a whirlwind UK tour aimed at drumming up last-minute support from the devolved administrations.
(13) The social responsibilities which devolve on monitors, the authorities, both sides of industry and the general public as a result of the establishment of monitoring systems are discussed.
(14) In his paper, Where is the peace dividend?, Knox contrasts the quality of life in the poorest areas, using the devolved Belfast government’s category of neighbourhood renewal areas (NRAs), with those that are not deemed to be in need of major socio-economic investment.
(15) This convention says that Westminster should not legislate on a matter which is normally devolved unless Holyrood has given its consent.
(16) He has signed 28 modest "city deals" with authorities to bring local control over areas from devolved transport funding to skills budgets, while – potentially – delivering extra money from the Treasury to Greater Manchester as the local economy grows.
(17) The new 14-strong BBC board will have four non-executive board members representing each of the devolved nations, appointed in the same way as the BBC chair.
(18) However, such a move is unlikely to win the backing of the nationalist SDLP or Alliance party, and in turn would create internal demands from within the DUP to also leave the devolved administration.
(19) Calling for a full re-evaluation of the union, Jones hailed the UK government's decision this month to offer the Welsh assembly new tax-raising and borrowing powers, but said the UK needed to have consistent ways of devolving power.
(20) Jarosław Kaczyński, the head of the governing PiS party, has already used the UK’s leave vote to call for thorough reform of the EU, arguing that a new European treaty devolving more power to member states is the only way to prevent further disintegration of the bloc.