(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Disparage
Definition:
(v. t.) To match unequally; to degrade or dishonor by an unequal marriage.
(v. t.) To dishonor by a comparison with what is inferior; to lower in rank or estimation by actions or words; to speak slightingly of; to depreciate; to undervalue.
(n.) Inequality in marriage; marriage with an inferior.
Example Sentences:
(1) (“The Dynasty of Bush” sounds like a terribly disparaging term for Linda Evans, Kate O’Mara and Joan Collins .
(2) US diplomats disparaged New Zealand's reaction to a suspected Israeli spy ring as a "flap" and accused New Zealand's government of grandstanding in order to sell more lamb to Arab countries, according to leaked cables.
(3) For the man who created the " specialist in failure " aphorism to disparage a fellow manager, it is obvious how much that would hurt.
(4) I’m hoping that he will actually raise the level of discussion,” Sullivan said, “and that he won’t just disparage everything with a tweet.
(5) There had been suggestions that Cameron had been caught off camera earlier on Saturday making disparaging remarks about Terry to Obama.
(6) On the left is the favourite, Spanish-born Hidalgo, 54, protégée of current mayor Bertrand Delanoë and disparagingly referred to as la dauphine (the heiress).
(7) • The Wall Street Journal uncovers communications between Sony and Marvel discussing a Spider-Man crossover and speaking disparagingly about Spider-Man star Andrew Garfield.
(8) The Republican move appears to be intended in part to highlight Republican disparagement of Barack Obama as the "food stamp president" because record numbers of Americans now claim the benefit, doubling the cost of the programme since 2008 to $80bn a year.
(9) Roginsky said in the suit that she was punished for not disparaging the former Fox News host Gretchen Carlson after she filed a sexual harassment suit against Ailes.
(10) The main finding of this study consists of an interaction between the personality factor anxiety and the feedback variable: High-anxiety subjects prefer test-disparaging information significantly more in the negative feedback condition than in the positive feedback condition, whereas low-anxiety subjects show no difference in preference for test-related information as a function of the feedback condition.
(11) However, one of the channel's British reporters, Sara Firth, appeared to go off message with a series of disparaging tweets in which she said the channel's reporters were engaged in lies.
(12) Axelrod admitted that Democratic supporters would have been disappointed that Obama had not raised strong issues such as the Republican position on women's rights, or the secret video showing Romney disparaging 47% of voters as freeloaders or his record as chief executive of the investment fund Bain Capital.
(13) Rather than honoring their sacrifice and recognizing their pain, Mr Trump disparaged the religion of the family of an American hero,” Collins wrote.
(14) Unfortunately, such methods are often inappropriately disparaged or ignored by epidemiologists.
(15) In addition, the voices of schizophrenic patients are predominantly disparaging, call approbrious names, or are accusatory.
(16) Critics were quick to disparage Obama's achievement as a meaningless compromise.
(17) Facebook Twitter Pinterest Abbott disparaged the fund at the time, comparing it to a domestic fund championed by the former Greens leader Bob Brown , which he wants to abolish.
(18) And despite my disparaging remarks about quite what did Tony achieve from his premiership the fact is if I had to choose between the Blairites and the Brownites I would choose the Blairites."
(19) The Labour leader said he would never disparage David Cameron in the same way, even though he believes the prime minister's policies are "profoundly misguided".
(20) More than 20% of the children--equal proportions of girls and boys--had self-perceptions that seriously underestimated their actual high abilities, and displayed a corresponding pattern of disparaging self- and other-achievement attitudes.