(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Humiliate
Definition:
(v. t.) To reduce to a lower position in one's own eyes, or in the eyes of others; to humble; to mortify.
Example Sentences:
(1) The result will be yet another humiliating hammering for Labour in a seat it could never win, but hey, never mind.
(2) Nickname: SuperSarko the Omnipresident Quote: "What made me who I am now is the sum of all the humiliations suffered during childhood."
(3) No one deserves to walk out of the theatre feeling scared, humiliated or rejected.
(4) Under Xi some of the party’s most powerful figures have been humiliated and jailed as part of a high-profile anti-corruption campaign that has seen hundreds of thousands of party officials disciplined across the country.
(5) In a recent article , Martin Jacques comments on how New Labour, which built its fortunes on "there being no alternative", is now being forced into the humiliating circumstances of having to find one.
(6) During interviews, married couples experiencing infertility reported emotional reactions such as sadness, depression, anger, confusion, desperation, hurt, embarrassment, and humiliation.
(7) Sarkozy, 59, had been tipped to win the leadership vote and indeed gained a clear majority, which avoided the humiliation of a second round of polling.
(8) What hard work that must be, especially if the humiliation is so public!
(9) The democratically elected usually manage to leave with some dignity intact – even if in Britain the removal is often criticised for its humiliating haste.
(10) There was no repeat of last season's humiliation but it told of another Liverpool exertion against Oldham Athletic that Brendan Rodgers took pride only in a competitive Anfield appearance for his son, Anton.
(11) It became clear, as Bourguiba went on, that he had two objectives in mind: to deflate and mildly humiliate the young Nasserist Libyan, and to outline his vision of the Arab world.
(12) 1.49am BST Michael Aston writes: Gota feeling this is going to be a thrashing, a major and total beat down... After watching the Spurs humiliate the Heat and Oranje murder Spain...this has a horror show Full moon Friday the 13th nightmare for NY written all over it.....then again, triple OT would be fun too Triple OT?
(13) She isn't sure – though, like Freud, she defines her anxiety as a threat that is objectless, and located in the future – such as ruination or humiliation (unlike fear, which is a response to a specific and immediate threat to one's safety).
(14) "The more of us who stand up, the less we can be humiliated.
(15) This kind of humiliation is already felt by many in this country.
(16) Detainees have seen their time allowed outside cells slashed, and been forced to undergo humiliating body cavity searches if they want to speak to lawyers, it has been claimed.
(17) What promised to be a day of utter humiliation had turned into yet another day of glory.
(18) The tribunal said the conduct had "the effect of violating the claimant's dignity or creating an intimidating, hostile, degrading, humiliating or offensive environment".
(19) Brown made mincemeat of a succession of shadow chancellors, taunting them with the contrast between the strong growth and healthy public finances under Labour and the humiliation visited upon John Major's government on Black Wednesday.
(20) A later speaker, Salah el-Ghazal, referred to Gaddafi's "humiliating" death, saying: "This is the humiliating end that God wanted to set as example for anyone who practices the worst forms of injustice … against their people," he said.