(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Regrade
Definition:
(v. i.) To retire; to go back.
Example Sentences:
(1) The subjects then used one of three treatment regimens, were retested for accumulated plaque and regraded.
(2) In Wales, the education minister, Leighton Andrews, ordered the WJEC exam board to regrade Welsh students' English papers.
(3) After 30 minutes, a second injection of placebo or naloxone was given, and the patient was regraded a third time.
(4) Challenged on whether he or anyone else should do anything to restore or change the grades achieved by pupils in England in June, Gove said: "If we were to regrade, or firstly if I were to instruct Ofqual or exam boards to regrade, I would destroy the independence of the regulator.
(5) Michael Gove has condemned the "irresponsible and mistaken" decision of the Welsh education minister, Leighton Andrews, to intervene in the disputed GCSEs grades by ordering a regrading exercise.
(6) Both the location and the dimensions of the wound as well as the breaking strength of the injured muscles remained inside such narrow limits that the trauma can be regraded as constant.
(7) Areas identified by others as area 3a should probably be regraded as parts of area 3b.
(8) The regulator insisted it would be inappropriate for either of the sets of exams to be regraded.
(9) Five minutes later, the same observer regraded the patient.
(10) The documents set out their case for a regrading of GCSE English papers taken by pupils this summer.
(11) Two thousand 300 students who took exams set by the Welsh exam board WJEC in Wales have already been regraded on the orders of the Welsh government, which regulates exams set there.
(12) There has been, as Guy Standing remarks in The Precariat , an orgy of regrading and redefining jobs as less skilled so that they qualify for lower wages; there has also been a growing confidence that employers do not need to pay higher wages in every annual wage round.
(13) The alliance is demanding Ofqual , the exam regulator in England, orders a regrade or face moves to force a judicial review in the high court.
(14) The women accepted a pay increase, still less than the men, but the regrading issue was not resolved until after another strike years later, in 1984, when they were finally classified as skilled workers.
(15) All cases were regraded according to a classification of Isaacson et al into high grade and low grade B-cell mucosa associated lymphoid tissue lymphoma.
(16) There was no difference between SLE and progressive polyarthritis as regrads the cold precipitation of rheumatoid factors.
(17) The common misconception of Norrie's disease being regraded as microphthalmia or hereditary corneal dystrophy instead of phthisis is noted.
(18) All lesions were regraded blind and twice by two pathologists.
(19) If a restructuring is essential, neither they nor I can see any reason why Marie and her colleagues shouldn’t have their jobs regraded and their pay preserved.
(20) It is being brought by an alliance of pupils, schools, councils and professional bodies, who want the students regraded after the boundary for a grade C in GCSE English was raised between January and June.