(a.) Reduced in rank, character, or reputation; debased; sunken; low; base.
(a.) Having the typical characters or organs in a partially developed condition, or lacking certain parts.
(a.) Having steps; -- said of a cross each of whose extremities finishes in steps growing larger as they leave the center; -- termed also on degrees.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Mortified
Definition:
() imp. & p. p. of Mortify.
(imp. & p. p.) of Mortify
Example Sentences:
(1) she shudders – she has declined all reality TV invitations, and the closest she has ever come to a wardrobe malfunction was a minor ding-dong over some exposed thigh once while presenting Crimewatch, about which she was mortified.
(2) EPA Gazza’s Italia 90 tears were but a trickling tributary compared with the Amazon of anguish unleashed by the shell-shocked hosts during their mortifying 7-1 loss to Germany.
(3) Karen Harding later described herself as “mortified”.
(4) He added that the situation was equally bad for his two sons, who were mortified by the pictures published in the News of the World.
(5) I don't use my kids' real names on my blog and I try to avoid writing anything that would have mortified me growing up, but might they resent me later?
(6) Farage prefaced his comments with a prediction that he was sure the other leaders would be “mortified that I dare to even talk about it”.
(7) He is toughest of all on himself: nearly 50 years on he is still mortified by his rhyming of "woman" with "human" in a song that got yanked from Anyone Can Whistle .
(8) "A mortifying and appalling experience," said one, while another fan posted on the standup's Facebook page: "Absolutely awful.
(9) Smith replied: “It has been the most mortifying experience for me in this contest to have been painted as sexist, because it’s the last thing I am.
(10) It was mortifying, actually.” “But you decided to play into it?” I ask her.
(11) They’d be mortified if they were caught doing that to LGBT people or Muslims.
(12) The presenter apologised and said he was "mortified" by the accusation .
(13) After one particularly mortifying Saturday afternoon when she saw me in the Wimpy with – the horror of it all!
(14) The story of his life mortified him and sent him scurrying for excuses.
(15) My hope is that the government of Sheikh Hasina might actually be mortified by this letter.” Bangladesh must act on these brutal attacks on bloggers | Letters Read more The letter comes after the blogger Ananta Bijoy Das was hacked to death last week on a crowded street in Sylhet , Bangladesh’s fifth-largest city.
(16) I have plenty of Labour-voting friends who are happy to cheer Venezuelan nationalism, but who would be mortified to be called British nationalists.
(17) Read it as a teenager and you wince for poor mortified Lizzie and Jane, thinking perhaps of times when our own mother said the wrong thing.
(18) He added: "I am mortified to have done this, because it breaches the most basic ethical rule: don't do to others what you don't want them to do to you.
(19) I’d be mortified if Boris Johnson was made leader of the Tory party, because it will say something profoundly awful about British politics.” “I think he is a showman, and an effective class clown if you like, but the class clown tends to be disruptive, as I think he would be if he had the chance to put his silly views into practice.” The Conservative former chancellor Norman Lamont also came to Johnson’s defence, saying it was a “fact there were fascist theorists who believed very strongly in a united Europe”.
(20) When Aston Pride ended this March, local people were mortified at receiving no recognition, not even a junior official from Eric Pickles's Department for Communities to visit, or a letter of praise for being the top NDC after all those years of giving so much and overcoming such obstacles.