(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Ignominious
Definition:
(a.) Marked with ignominy; in curring public disgrace; dishonorable; shameful.
(a.) Deserving ignominy; despicable.
(a.) Humiliating; degrading; as, an ignominious judgment or sentence.
Example Sentences:
(1) However, internal divisions arose within the army, and by July 1985 Obote was once again on the ignominious road to exile, first to Kenya, and then to Zambia, where fellow independence leader Kenneth Kaunda allowed him to stay.
(2) Ignominy On the radio, he spoke of his intention "to resist by all means, at the cost of my life: to leave to the ignominy of history the lesson of those who have force but not reason."
(3) Tesco's ignominious exit from the US will grab all the headlines but the truth is that even without the Fresh & Easy debacle the supermarket would probably still have seen its profits fall for the first time in 20 years.
(4) Anglo Irish Bank, which was the preferred lender for property speculators and builders, epitomised the rise and ignominious fall of the Celtic Tiger economy.
(5) I see the possibility of terminal, and potentially ignominious decline."
(6) The conservative New Democracy party – the dominant force in a coalition lead by the outgoing prime minister Antonis Samaras – suffered ignominious defeat, collapsing to 76 seats in the 300-seat parliament.
(7) For months, Nick Clegg has been itching to take aim at what he regards as the Conservatives' dangerous approach to the EU, which could set Britain on the path to an ignominious exit.
(8) Instead they lost 2-1 to tiny Iceland , in another ignominious exit from Europe.
(9) This time, he has a place.” ’88, ’08 and right now Biden’s first presidential run, in 1988, ended ignominiously.
(10) Yet this ignominious retreat became enshrined as a glorious victory; the guts of survivors made it a founding myth.
(11) He now joins an ignominious list of individuals stripped of their honours, including Robert Mugabe, the president of Zimbabwe, and Anthony Blunt, who spied for Russia.
(12) Friday’s dramatic judgement brings an abrupt and ignominious end to Park’s four years in office – the most dramatic development yet in a scandal that has gripped and horrified South Koreans in equal measure.
(13) The strange thing, perhaps, is that Roy Hodgson spent the day in Paris but chose not to make a personal check on the team who will be trying to inflict ignominy upon England in Nice on Monday.
(14) What can we infer from Lidl's foray into everyday British life – that something once a source of ignominy has become normalised?
(15) With one ignominious intervention, the window has now been moved, and various anti-Muslim bigots can say: “Well Donald Trump has gone too far, but here’s what I would say instead.” They suddenly become the more moderate alternatives where once they would have been seen as themselves extreme.
(16) Which is basically what I'd have been doing if I wasn't in the show... Also, I think most people have experienced the agony and the ignominy of unrequited love...
(17) But some commentators have made comparisons with the ignominious departure of Angus Deayton, longtime chair of the topical quiz Have I Got News For You .
(18) Much of the capital of Anbar province, the scene of an ignominious defeat of the Iraqi military by Islamic State in May and now largely won back after a gruelling offensive backed by 600 US-led coalition airstrikes, is in ruins.
(19) The Sounders choked on the run-in and despite Clint Dempsey finally scoring in the last game of the regular season, it wasn’t enough to overhaul LA for third place in the West, and avoid the ignominy of the wild card game.
(20) The wonderful Scottish writer John Burnside, in his book I Put a Spell on You , makes an apt comment that the hit song "Don't leave me this way" is a pathetically ignominious response to a departing lover.