(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
(1) Haki's naivety about English detective fiction is more than matched by Latimer's ingenuous excitement as Haki describes to him Dimitrios's sordid career, and he decides it would be fun to write the gangster's biography.
(2) It might be really sordid and bad sexual etiquette, but whatever else it is, it is not rape or you bankrupt the term rape of all meaning."
(3) Scarcely a day goes by without another apology for past failures, another gimmicky new policy, another sordid attempt to grab headlines.
(4) A former police officer is less complimentary: "The clientele in these places are by definition pretty sordid, highly manipulative and sleazy," he says.
(5) As Margarito and Inez argue over what really happened that day in Culiacan, it seems that they are no longer describing yet another sordid killing in the endless war on drugs.
(6) How could any organisation survive the sordid revelations that emerged at the Leveson inquiry, costing the Murdoch empire millions in compensation and legal fees, along with the closure of a flagship title?
(7) He recalled the stench and listening to the screams of others echoing through their sordid dungeon.
(8) The "titillating details" of the "sordid affairs" of the Anna Nicole saga "enticed" Bahamians and changed the face of the island's politics, two confidential memos sent by the embassy in Nassau reveal.
(9) "Of all the sites, it was the most depressing and slightly sordid," she says, "while other places often had an air of melancholy or seemed slightly otherworldly at dawn.
(10) Wilde takes no prisoners from the very outset: “The chief advantage that would result from the establishment of socialism is, undoubtedly, the fact that socialism would relieve us from that sordid necessity of living for others.” It’s a very Wildean, quasi-epigrammatic reversal – the reader expects something worthy, collectivist and altruistic, instead he gets something that’s irreverent, individualistic and apparently selfish.
(11) To begin with, it was a different kind of image problem: in Georgian society gin was considered rackety and sordid, not fusty and old-fashioned as it was in the swinging 60s.
(12) Often only one – and sometimes no – carriage door would open when they pulled into a station, and in summer they were “cooled” only by the methodical sweep of a begrimed metal fan that just pushed the sordid air about.
(13) The principle is a simple one: it involves national resources going into education, health and housing, instead of being siphoned off into the offshore accounts of the super-rich or squandered on sordid overseas conflicts, instigated by the inadequate for the profit of their paymasters.
(14) In her 1963 novel A Summer Birdcage , Margaret Drabble’s narrator Sarah describes a “loathsome flat” in the King’s Road, Chelsea, and an “unspeakably sordid” place in Highgate.
(15) Again, my first instinct is that they must have been rubbernecking, the sordid allegations having made HRH a rather grim sort of draw, or at the very least not as ferociously dull and pointless as the rest of the apres-ski programme .
(16) One letter said: "Will some evil person leak the entire proceedings and all the sordid details so that the irresponsible global media … can really get their teeth into them?"
(17) Two years ago, in a joint interview with Ruth Rendell, the writers were asked by a Daily Telegraph reporter, "how two respectable, middle-class ladies" could be involved in the "sordid world of crime fiction?"
(18) At the same time, the cable adds, the "titillating details of Anna Nicole's sordid affairs have enticed the Bahamian public to give renewed focus to government indiscretions".
(19) This is a potentially serious point, seeing as to require any priest to solemnise what he believes to be sordid would be to mandate hypocrisy and thereby demean the prospective services.
(20) But the release of three separate reports on Friday; from the Metropolitan police and the NSPCC, the Crown Prosecution Service and from Surrey police, has shed harsh light on what Commander Peter Spindler of Scotland Yard labelled a sordid tale of a larger than figure who had "groomed the nation".