(a.) Hurtful; noxious; destructive; pernicious; as, a deleterious plant or quality; a deleterious example.
Example Sentences:
(1) There was however no difference in the cross-sectional studies and no significant deleterious effect detected of tobacco use on forearm bone mineral content.
(2) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(3) Ecological risk assessments are used by the US Environmental Protection Agency (US EPA) and other governmental agencies to assist in determining the probability and magnitude of deleterious effects of hazardous chemicals on plants and animals.
(4) The average IEMG of the muscles in the relaxation phase of contraction remained unaltered by fatigue, while a marked deleterious change in the relaxation-time variables (p less than 0.001) occurred concomitantly.
(5) The results demonstrate that the addition of pulsatile flow to coronary perfusion minimized the deleterious effects of prolonged ventricular fibrillation on myocardial performance.
(6) He concludes that steroid contraceptives always have a deleterious effect on glucose tolerance, although not usually to the point of causing diabetes.
(7) While measles virus caused extensive damage to nervous tissue, the SSPE strains, in general, exerted a less deleterious effect.
(8) It is concluded that intestinal bypass in rats has a more deleterious effect than resection, and this seems to be more pronounced when the excluded segment is anastomosed to the colon.
(9) The homdr mutation is unstable and probably deleterious to the cell.
(10) The biological effects mediate by cachectin may be beneficial or deleterious to the body, depending on the quantity produced, duration of cell exposure and further biochemical mediators in the environment of the target cells.
(11) Although many studies report deleterious effects of inbreeding on prereproductive mortality (death before age 20 years), such effects are usually measured in terms of genetic load, a concept much debated in the literature.
(12) Moreover, the mechanical denudation technique did not deleteriously affect smooth muscle because vasoconstrictor and vasodilator responses to nonendothelial-dependent drugs were the same before and after denudation.
(13) University of Wisconsin solution can extend hypothermic cardiac preservation and has no deleterious effects on long-term myocardial function (up to 45 days).
(14) Phospholipase A2, which is known to be activated in ischemia, destroys the microstructure of myocardial cells, seems deleterious to oxygen transport to cytochrome a,a3.
(15) A more objective consideration relates to the observed late, progressive deleterious influences of hyperfiltration imposed upon the reduced population of surviving nephrons (3); would this process been exaggerated by improved perfusion?
(16) Sex hormone deficiency, as well as chronic illness, malnutrition, and childhood immobilization, has deleterious effects on growth and modeling, ultimately reducing peak bone mass and setting the stage for osteoporosis in later life.
(17) Myocardial transformation, along with its energy economizing effect, failed to compensate for unfavorable energetic consequences of structural dilatation and therefore the reduced ventricular efficiency is assumed to be another deleterious factor in the dilated failing heart.
(18) We conclude that storage at 22 degrees C had deleterious effects on the GP Ib content of platelets.
(19) All of these alleles have apparently resulted from gene conversion events that have transferred deleterious mutations from the CYP21A pseudogene to CYP21B.
(20) Within science, there are forces that weaken genuine scientific discussion, and these need at least to be explicated so that their deleterious effects can be minimized.
Effect
Definition:
(n.) Execution; performance; realization; operation; as, the law goes into effect in May.
(n.) Manifestation; expression; sign.
(n.) In general: That which is produced by an agent or cause; the event which follows immediately from an antecedent, called the cause; result; consequence; outcome; fruit; as, the effect of luxury.
(n.) Impression left on the mind; sensation produced.
(n.) Power to produce results; efficiency; force; importance; account; as, to speak with effect.
(n.) Consequence intended; purpose; meaning; general intent; -- with to.
(n.) The purport; the sum and substance.
(n.) Reality; actual meaning; fact, as distinguished from mere appearance.
(n.) Goods; movables; personal estate; -- sometimes used to embrace real as well as personal property; as, the people escaped from the town with their effects.
(v. t.) To produce, as a cause or agent; to cause to be.
(v. t.) To bring to pass; to execute; to enforce; to achieve; to accomplish.
Example Sentences:
(1) Indicators for evaluation and monitoring and outcome measures are described within the context of health service management to describe control measure output in terms of community effectiveness.
(2) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(3) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(4) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(5) AEDs may also have differential effects on nighttime sleep.
(6) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(7) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
(8) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
(9) Age difference did not affect the mean dose-effect response.
(10) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(11) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(12) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(13) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(14) Omission of K(+), Ca(++) or Mg(++) had no effect on uptake.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(17) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(18) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(19) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(20) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).