(a.) Hurtful; noxious; destructive; pernicious; as, a deleterious plant or quality; a deleterious example.
Example Sentences:
(1) There was however no difference in the cross-sectional studies and no significant deleterious effect detected of tobacco use on forearm bone mineral content.
(2) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(3) Ecological risk assessments are used by the US Environmental Protection Agency (US EPA) and other governmental agencies to assist in determining the probability and magnitude of deleterious effects of hazardous chemicals on plants and animals.
(4) The average IEMG of the muscles in the relaxation phase of contraction remained unaltered by fatigue, while a marked deleterious change in the relaxation-time variables (p less than 0.001) occurred concomitantly.
(5) The results demonstrate that the addition of pulsatile flow to coronary perfusion minimized the deleterious effects of prolonged ventricular fibrillation on myocardial performance.
(6) He concludes that steroid contraceptives always have a deleterious effect on glucose tolerance, although not usually to the point of causing diabetes.
(7) While measles virus caused extensive damage to nervous tissue, the SSPE strains, in general, exerted a less deleterious effect.
(8) It is concluded that intestinal bypass in rats has a more deleterious effect than resection, and this seems to be more pronounced when the excluded segment is anastomosed to the colon.
(9) The homdr mutation is unstable and probably deleterious to the cell.
(10) The biological effects mediate by cachectin may be beneficial or deleterious to the body, depending on the quantity produced, duration of cell exposure and further biochemical mediators in the environment of the target cells.
(11) Although many studies report deleterious effects of inbreeding on prereproductive mortality (death before age 20 years), such effects are usually measured in terms of genetic load, a concept much debated in the literature.
(12) Moreover, the mechanical denudation technique did not deleteriously affect smooth muscle because vasoconstrictor and vasodilator responses to nonendothelial-dependent drugs were the same before and after denudation.
(13) University of Wisconsin solution can extend hypothermic cardiac preservation and has no deleterious effects on long-term myocardial function (up to 45 days).
(14) Phospholipase A2, which is known to be activated in ischemia, destroys the microstructure of myocardial cells, seems deleterious to oxygen transport to cytochrome a,a3.
(15) A more objective consideration relates to the observed late, progressive deleterious influences of hyperfiltration imposed upon the reduced population of surviving nephrons (3); would this process been exaggerated by improved perfusion?
(16) Sex hormone deficiency, as well as chronic illness, malnutrition, and childhood immobilization, has deleterious effects on growth and modeling, ultimately reducing peak bone mass and setting the stage for osteoporosis in later life.
(17) Myocardial transformation, along with its energy economizing effect, failed to compensate for unfavorable energetic consequences of structural dilatation and therefore the reduced ventricular efficiency is assumed to be another deleterious factor in the dilated failing heart.
(18) We conclude that storage at 22 degrees C had deleterious effects on the GP Ib content of platelets.
(19) All of these alleles have apparently resulted from gene conversion events that have transferred deleterious mutations from the CYP21A pseudogene to CYP21B.
(20) Within science, there are forces that weaken genuine scientific discussion, and these need at least to be explicated so that their deleterious effects can be minimized.
Noxious
Definition:
(a.) Hurtful; harmful; baneful; pernicious; injurious; destructive; unwholesome; insalubrious; as, noxious air, food, or climate; pernicious; corrupting to morals; as, noxious practices or examples.
(a.) Guilty; criminal.
Example Sentences:
(1) At both 24 h and 1 week, the inflamed paw showed pronounced supersensitivity to the antinociceptive action of morphine against noxious pressure.
(2) "It looks as if the noxious mix of rightwing Australian populism, as represented by Crosby and his lobbying firm, and English saloon bar reactionaries, as embodied by [Nigel] Farage and Ukip, may succeed in preventing this government from proceeding with standardised cigarette packs, despite their popularity with the public," said Deborah Arnott, chief executive of the health charity Action on Smoking and Health.
(3) Noxious conditioning stimulation of a tooth led to a temporary decrease of the threshold for the jaw-opening reflex elicited from a contralateral or adjacent tooth; only conditioning stimulation at an intensity producing a marked arousal reaction was effective in this respect.
(4) Results showed the greatest inhibition of noxious stimulus perception with Innovar-Vet, lesser inhibition with ketamine-xylazine and ketamine-diazepam, and the least obtunding of nociception with pentobarbital.
(5) Furthermore the noxious stimuli were completely ineffective from 10-15 min following the lidocaine injection while the non-noxious stimuli maintained their efficacy.
(6) Experiments using normal human subjects were performed to determine the effect of a putative analgesic, transcutaneous electrical nerve stimulation (TENS), on the perception of noxious thermal stimuli and also to examine critically the general applicability of signal detection theory (SDT) to the evaluation of analgesic agents.
(7) Rats inoculated in the tail-base with killed Mycobacterium butyricum developed an arthritic swelling and inflammation of the limbs accompanied by a hyperalgesia to noxious pressure applied thereto.
(8) Complete transection of the thoracic spinal cord eliminated both thermally elicited responses and orienting responses to noxious and tactile mechanical stimulation of the hindlimbs.
(9) This situation has contributed to exposure of sandblasters to hazardous levels of respirable free silica, and is reviewed here to prevent a continuation of the incompatibility of these and other standards for respiratory protection with the actual exposures to various noxious inhalants in the workplace.
(10) Effects of noxious electrical tooth stimulations and intraarterial administration of bradykinin or inhalation of volatile anesthetics on substance P content in the diencephalon-mesencephalon, pons-medulla and the spinal cord were examined in the rat.
(11) Surface airway epithelium is frequently injured by noxious inhaled agents, epithelial wound repair may be an important process by which the epithelial barrier integrity is maintained.
(12) Cough and bronchoconstriction are airway reflexes that protect the lung from inspired noxious agents.
(13) Pb also appeared to unmask an afterdischarge in some neurons following noxious mechanical stimulation.
(14) Neurons were first classified as on-cells if they fired faster during noxious pinch or as off-cells if they fired slower.
(15) These data indicate the antinociception from PAG stimulation is not equally distributed throughout the body, and that the intensity of the noxious stimulus influences the threshold for SPA.
(16) Profound inhibitions of the second phase were also produced by tactile segmental stimulation and noxious stimuli applied to widespread areas of the body (diffuse noxious inhibitory controls).
(17) It hasn't been reported that the neurons in somatosensory area I (SI) may respond to the noxious stimulation.
(18) Stimuli used to activate the cells orthodromically were graded innocuous and noxious mechanical stimuli, including sinusoidal vibration and thermal pulses.
(19) This cannot be explained by metabolic activation of the halogenated hydrocarbons but could be due to a noxious effect on the mitotoc spindle.
(20) Suppression of the tail flick response to noxious heat and paw withdrawal response to noxious pressure were produced by electrical stimulation of arcuate nucleus of the hypothalamus (ARH) in pentobarbital anesthetized rats.