(n.) The act of demonstrating; an exhibition; proof; especially, proof beyond the possibility of doubt; indubitable evidence, to the senses or reason.
(n.) An expression, as of the feelings, by outward signs; a manifestation; a show.
(n.) The exhibition and explanation of a dissection or other anatomical preparation.
(n.) (Mil.) a decisive exhibition of force, or a movement indicating an attack.
(n.) The act of proving by the syllogistic process, or the proof itself.
(n.) A course of reasoning showing that a certain result is a necessary consequence of assumed premises; -- these premises being definitions, axioms, and previously established propositions.
Example Sentences:
(1) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(4) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(5) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(6) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(7) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(8) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(9) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(10) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(11) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(12) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(13) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(14) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(15) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(16) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
(17) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(18) In 1 of the 3, anterior capsular detachment was also demonstrated radiographically and confirmed surgically.
(19) This result demonstrates that branching enzyme belongs to a family of the amylolytic enzymes.
(20) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
Mimicry
Definition:
(n.) The act or practice of one who mimics; ludicrous imitation for sport or ridicule.
(n.) Protective resemblance; the resemblance which certain animals and plants exhibit to other animals and plants or to the natural objects among which they live, -- a characteristic which serves as their chief means of protection against enemies; imitation; mimesis; mimetism.
Example Sentences:
(1) Antigenic mimicry by T. cruzi antigens sharing epitopes with host macromolecules has been implicated in the pathogenesis which is thought to have a significant autoimmune component.
(2) To investigate the possible involvement of epitopes shared by microbial antigens and host self-components in initiation of autoimmunity (molecular mimicry), a sequence data bank was screened for proteins containing an amino acid motif identical or related to ERKRR.
(3) The homology thus revealed not only lends strong support to mechanisms of autoimmunity that invoke the theory of molecular mimicry of viral proteins, but also suggests a rationale for the skeletal muscle target of polymyositis.
(4) They include antigenic variation, antigenic polymorphism, antigenic mimicry and direct interference with the generation of the host immune response.
(5) The basis of the stimulation of this group of autoantibodies is at least in part due to antigenic mimicry between the envelope protein VP3 of LDV and determinants of intermediate filaments, since a panel of monoclonal antibodies cross-reacts with both.
(6) The role of molecular mimicry in the spondyloarthropathies was investigated with respect to the epitopes involved.
(7) The possibility of molecular mimicry (antibody cross-reactivity between LCM and RBC membrane epitopes) was considered but appeared unlikely since the RBC antibody eluates gave no signal in an LCM-specific ELISA (which showed an ever increasing serum titer of virus-specific antibody).
(8) To examine how mimicry was influenced by a person's power and the status of those around them, Carr asked 55 volunteers to watch videos of high-status people (such as a doctor or business leader) or low-status people (a worker in a fast food restaurant, say, or a rubbish collector) either being happy or angry.
(9) Although several means have been hypothesized to play a role in disease, a widely accepted mechanism for viral-induced autoimmunity is molecular mimicry.
(10) In an effort to understand the structural basis for antigen mimicry by internal image antibodies, we determined the variable (V) region sequences of two mouse mAbs that mimic the rabbit Ig a1 allotype.
(11) Phenotypic switching and molecular mimicry may also provide the organism with an arsenal of mechanisms to evade host defenses.
(12) The binding of antibodies in the sera of patients with Lyme arthritis to the NH2-terminal region of the flagellar protein, a region with sequence homology to the flagellar proteins of other bacterial species, suggests the possibility that antigenic mimicry contributes to the immunopathogenesis of Lyme disease.
(13) Antigenic mimicry has been demonstrated to be operative, since they are cross-reactive to viral proteins.
(14) Although the thickness of the soft tissue is dependent on exogenous factors, such as nutrition, mimicry, and so forth, the dimensions of the bony nose apparently also influence the skin depths to some extent.
(15) Molecular mimicry or epitope similarity between group A streptococcal M proteins and myosin may contribute to the presence of heart reactive antibodies in acute rheumatic fever.
(16) Our results show that the macromolecular assemblage approach bears immunological mimicry of the gp120 of HIV virus and may lead to useful vaccines against HIV infection.
(17) Variations in the antigenic behaviour of parasites and their immunological mimicry by uptake of substances from the host and their immunosuppressive action are discussed.
(18) Hence it is not likely to be involved in the pathogenesis of HAM through molecular mimicry.
(19) It has been suggested that molecular mimicry might be a reason for autoimmunity as a result of immunological cross reactivity.
(20) Other mechanisms including antigenic mimicry by capsular polysaccharides and antigenic masquerade by immunoglobulin fragments confer additional resistance to the extracellular life style of these organisms.