(a.) Softening; mollifying; soothing; assuasive; as, oil is demulcent.
(n.) A substance, usually of a mucilaginous or oily nature, supposed to be capable of soothing an inflamed nervous membrane, or protecting it from irritation. Gum Arabic, glycerin, olive oil, etc., are demulcents.
Example Sentences:
(1) This therapeutic benefit has been attributed to a cytoprotective and demulcent action.
(2) Concomitant treatment with cimetidine or demulcents did not seem to prevent episodes of bleeding.
(3) Most children had no symptoms and received no treatment except emesis or oral fluid and demulcents.
(4) Licorice (Glycyrrhiza glabra), a Mediterranean plant, has been used as an antidote, demulcent, and elixir folk medicine for generations in China.
(5) Ten-week saturation of the body with vitamin A and other vitamins, therapy with immunostimulants and surface demulcents and exfoliating agents resulted in a considerable improvement of the patient's condition.
Obtundent
Definition:
(n.) A substance which sheathes a part, or blunts irritation, usually some bland, oily, or mucilaginous matter; -- nearly the same as demulcent.
Example Sentences:
(1) The thigh and hip manifestations can obscure the primary intra-abdominal process either due to the obvious emphysema or to the obtunded abdominal signs secondary to associated neuropathy.
(2) Results showed the greatest inhibition of noxious stimulus perception with Innovar-Vet, lesser inhibition with ketamine-xylazine and ketamine-diazepam, and the least obtunding of nociception with pentobarbital.
(3) The use of wire stylets to facilitate passage of these tubes has increased the chances of unrecognized tracheal intubations, particularly in obtunded patients.
(4) Characteristic clinical features were present in 19 patients, including a gradual obtundation after the initial hemorrhage in 16 patients and small nonreactive pupils in nine patients (all with a Glasgow Coma Scale score of 7 or less).
(5) Kynurenic acid significantly obtunded these behavioral and physiological effects, particularly when given 60-75 min after the toxic insult.
(6) Addition of adenosine deaminase to fat cells isolated from cold-exposed rats did not normalize the lipolytic activity, suggesting that extracellular adenosine was not responsible for the obtunded lipolysis.
(7) A 59-year-old man was admitted because of frequent vomiting and obtundation in February 1982.
(8) Propofol was more effective than methohexitone at obtunding the hypertensive response to electroconvulsive therapy without causing significant hypotension.
(9) Thus, although low doses of glucocorticoids foster development of the coupling of beta-receptors to cellular transduction mechanisms, higher doses such as those used to stimulate lung function may lastingly obtund adrenergic sensitivity.
(10) Neurologic dysfunction is characterized by lethargy, obtundation, persistent vomiting, agitated delirium, and coma.
(11) The current indications for lavage are obtundation, unprotected airway, seizures, the need for urgent removal, and the tendency to form concretions.
(12) Histoplasmosis in the CNS may produce meningitis, single or multiple brain abscesses, and may present with either a clinical picture of obtundation or a deteriorating space-occupying CNS lesion.
(13) Other variables with strong predictive potential were age (P less than 0.001), the presence of multiple disease states (P less than 0.01), therapy with multiple drugs (P less than 0.01) and acute stroke or obtundation on admission (P less than 0.01).
(14) As projected by this study, scleral heterografts might well be used to obliterate bony undercuts and perhaps to obtund cystic cavities and other major bony defects.
(15) The patient became progressively more obtunded throughout the emergency department stay.
(16) The effects of 3H-epinephrine on the duration of block and on the time course of uptake and efflux of local anesthetic (14C-lidocaine hydrochloride) were determined in the infraorbital nerve of the pentobarbital-obtunded rat.
(17) Contraindications for gastric lavage are similar to those for emesis except that it may be safer to use in obtunded, comatose, or uncooperative patients.
(18) I have described a fatal case of GGS meningitis and endocarditis in a previously healthy 84-year-old who had obtundation, irritability, and cellulitis.
(19) The toxicity of dCF alone was minimal, except for one patient who became obtunded on day 5 following the first cycle of therapy.
(20) Symptoms occurred between 30-180 min with the onset of central nervous system depression, ataxia, waxing and waning obtundation, hallucinations, intermittent hysteria or hyperkinetic behavior.