(n.) A small cavern or hollow place in the side of a hill, or among rocks; esp., a cave used by a wild beast for shelter or concealment; as, a lion's den; a den of robbers.
(n.) A squalid place of resort; a wretched dwelling place; a haunt; as, a den of vice.
(n.) Any snug or close retreat where one goes to be alone.
(n.) A narrow glen; a ravine; a dell.
(v. i.) To live in, or as in, a den.
Example Sentences:
(1) Fractures which occur near the base of the dens have a low propensity to unite spontaneously.
(2) Significantly higher levels of c-myc gene expression were observed in tissues of HCC of the DEN group and in neoplastic nodules of the DEN-DES groups than in the DES and DEN-C group.
(3) The antibody response against flaviviruses tick-borne encephalitis (TBE), Kyasanur Forest disease (KFD), Murray Valley encephalitis (MVE), West Nile fever (WNF), Japanese B encephalitis (JE), dengue 2 (DEN-2), and yellow fever (YF) was studied in humans after administration of an inactivated TBE virus vaccine.
(4) ENU, in contrast with DEN, also resulted in a significant staining of nonparenchymal cells.
(5) A systematic study including morphologic, histologic, pathologic aspects of dens evaginatus was carried out and data were compared with those given in previous reports pertaining to dens evaginatus in other Asian countries.
(6) The data reflect differences in the behaviour of GR and AR in the atrophic BCLA and suggest a relative increase in sensitivity to glucocorticoids compared to androgens in the DEN muscle.
(7) We have now characterized in vivo Th-cell priming activity of one of these peptides (MVE 17, amino acids 356 to 376) and an analogous peptide derived from the E-glycoprotein sequence of the dengue (DEN) 2, Jamaica strain (DEN 17, amino acids 352 to 368).
(8) Particularly so, as Lord Denning put it "...without morality there can be no law."
(9) Rheumatoid arthritis, which produces anterior displacement of the atlas over the dens to more than 10 mm, neurologic symptoms, or untreatable pain must be stabilized by means of C1-C2 fusion.
(10) Most DEN virus strains, representing all 4 serotypes isolated from various parts of the tropics, were identical either visually of spectrophotometrically when infected cell culture fluids were used as sources of antigen.
(11) In the Mahale Mountains National Park of Tanzania, a group of about 33 chimpanzees were observed to surround a leopard den containing a mother and at least one cub and to drag out and kill the cub.
(12) A series of temperature-sensitive (ts) mutants of dengue virus type 2 (DEN-2, TH-36 isolate) were induced by treatment with 5-azacytidine.
(13) produces more potential foci of tumour growth than in the normal liver and (2) that the repeated doses of CCl4 leading to repeated phases of regeneration, after the dose of DEN, provide a promoting stimulus.
(14) The shelf life of the solid phase presensitized with monoclonal antibodies was 4 mth at -15 degrees C. DEN prototype viruses were still identified after storage at -15 degrees C for 1 yr or at room temperature for 1 mth.
(15) O6EG levels in DNA of Clara cell-enriched populations were found to be higher than O6EG levels in DNA of alveolar type II cell-enriched populations and macrophages following acute DEN treatment.
(16) The fiber orientation is dependent on the height of dens axis, mostly in the cranial caudal direction.
(17) At earlier stages of the neoplastic process (11 or 16 weeks after the second DEN dose), most adenomas were well-differentiated lesions with no atypia or focal grade 1 or 2 atypia.
(18) This technique is best applied in nontraumatic cases in which the dens is not seen clearly on the "open mouth view".
(19) This treatment raised the number of adenosine-5'-triphosphatase (ATPase)-deficient foci up to 5-fold, that of gamma-glutamyltranspeptidase (GGTase) and glycogen-positive foci 13- and 10-fold, respectively, after 12 weeks; 25 mg caused no effect compared to DEN-treated controls.
(20) The system consists of a) single carcinogenic dose of diethylnitrosamine (DEN), b) short-term dietary exposure to 2-acetylaminofluorene (2-AAF) sufficient to suppress growth of virtually all normal hepatocytes, and c) partial hepatectomy (PH) to actuate rapid growth of DEN-altered hepatocytes not suppressed by 2-AAF.
Diminutive
Definition:
(a.) Below the average size; very small; little.
(a.) Expressing diminution; as, a diminutive word.
(a.) Tending to diminish.
(n.) Something of very small size or value; an insignificant thing.
(n.) A derivative from a noun, denoting a small or a young object of the same kind with that denoted by the primitive; as, gosling, eaglet, lambkin.
Example Sentences:
(1) Age, histological type, number or location of the index diminutive polyps, were not associated with proximal lesions.
(2) The rate of removal of exogenous PGE2 in the hind limb circulation was not influenced by HC, suggesting that the diminution of PG release by HC results from the suppression of PG generation rather than from the enhancement of degradation.
(3) Incubation of freshly isolated rat hepatocytes with highly purified radiolabeled rat transferrin in weakly buffered medium in the presence of 10 mM ethanol resulted in a marked diminution of iron uptake by these cells, associated with a greater pH depression than in ethanol-free control studies.
(4) The effect was more pronounced in those patients with a greater basal excretion of THP and in those with a more significant diminution of their bone mass.
(5) After intact, cycling female mice received subcutaneous injections of antipain and leupeptin for 16 days, their uteri showed significant diminution in weight and total DNA when compared to untreated controls.
(6) The fibrosis of the gastric wall with motility disturbances, and the diminution of acid and pepsin production from damage to the glandular elements, would weigh against the addition of a vagotomy to the drainage procedure.
(7) The content of membrane lipids also diminished continuously up to 90 years of age, when a marked diminution in level of gangliosides and cerebrosides occurred, a result indicating a rapid reduction in amount of neuronal membranes and myelin.
(8) The tonic influences were expressed in an increase in the amplitude parameters of the responses of the visual cortex in conditions of the formation in the posterolateral nucleus of the thalamus of a focus of heightened excitability (anode polarization), and their perceptible diminution with potassium depression in this nucleus.
(9) Large loads of aspartate cause 20% diminution of glutathione in outer cortex, due entirely to changes in proximal tubule segments.
(10) Rabbits immunized with the flagella developed an immune response to the flagella but showed no statistically significant prolongation of incubation time or diminution of lesion severity when challenged intradermally with 4 X 10(3) Treponema pallidum organisms.
(11) Major changes include an early diminution in myofibrillar density, accompanied by a small reduction in mitochondrial density.
(12) Simultaneous treatment with both drugs resulted in a decrease in the quantity of immune complexes and a diminution of the migration inhibition.
(13) The results presented in this report suggest that the diminution of interphase cytoplasmic microtubules in tumor cells is probably due to the deficiency of microtubule organizing mechanism in interphase tumor cells.
(14) Animals irradiated with 1 Gy showed no diminution in plasma and ileal DAO activities through Day 13 relative to nonirradiated controls.
(15) Response to reimmunization was characterized by a significant acceleration and diminution of skin response, but not to the degree seen in an equivalent group who had received their primary immunization percutaneously.
(16) During the operation and the postoperative period various hemorheological and hemostasiological alterations acquire clinical significance: 1. hyperreagibility of platelets with increased aggregation and adhesion tendency 2. changes in fibrinogen, albumin, and globulin concentrations, which affect viscosity and red cell aggregation 3. impairment of red cell deformability 4. increase in clotting factors 5. disturbance of fibrinolysis characterized by diminution of plasmatic plasmin and increase in antiplasmin activity In addition, anesthetic techniques have also been shown to affect hemorheological and hemostasiological parameters.
(17) In dilute solution this is indeed observed, and the diminution in tetramer concentration when 30% of normal spectrin is replaced by alpha beta' dimers, amounts to only a small proportion.
(18) In contrast to acidosis induced in vivo, mitochondria from normal rats subjected to a diminution in medium pH, either by manipulation of HCO3 concentration or PCO2, significantly decrease NH3 production.
(19) All individuals manifested a marked diminution of CD4+ cells.
(20) Flow cytometric determination of DNA content in R3327AT-3 cells treated in vitro indicated a selective diminution of cells in the G2 and M phases of the cell cycle.