(n.) A small cavern or hollow place in the side of a hill, or among rocks; esp., a cave used by a wild beast for shelter or concealment; as, a lion's den; a den of robbers.
(n.) A squalid place of resort; a wretched dwelling place; a haunt; as, a den of vice.
(n.) Any snug or close retreat where one goes to be alone.
(n.) A narrow glen; a ravine; a dell.
(v. i.) To live in, or as in, a den.
Example Sentences:
(1) Fractures which occur near the base of the dens have a low propensity to unite spontaneously.
(2) Significantly higher levels of c-myc gene expression were observed in tissues of HCC of the DEN group and in neoplastic nodules of the DEN-DES groups than in the DES and DEN-C group.
(3) The antibody response against flaviviruses tick-borne encephalitis (TBE), Kyasanur Forest disease (KFD), Murray Valley encephalitis (MVE), West Nile fever (WNF), Japanese B encephalitis (JE), dengue 2 (DEN-2), and yellow fever (YF) was studied in humans after administration of an inactivated TBE virus vaccine.
(4) ENU, in contrast with DEN, also resulted in a significant staining of nonparenchymal cells.
(5) A systematic study including morphologic, histologic, pathologic aspects of dens evaginatus was carried out and data were compared with those given in previous reports pertaining to dens evaginatus in other Asian countries.
(6) The data reflect differences in the behaviour of GR and AR in the atrophic BCLA and suggest a relative increase in sensitivity to glucocorticoids compared to androgens in the DEN muscle.
(7) We have now characterized in vivo Th-cell priming activity of one of these peptides (MVE 17, amino acids 356 to 376) and an analogous peptide derived from the E-glycoprotein sequence of the dengue (DEN) 2, Jamaica strain (DEN 17, amino acids 352 to 368).
(8) Particularly so, as Lord Denning put it "...without morality there can be no law."
(9) Rheumatoid arthritis, which produces anterior displacement of the atlas over the dens to more than 10 mm, neurologic symptoms, or untreatable pain must be stabilized by means of C1-C2 fusion.
(10) Most DEN virus strains, representing all 4 serotypes isolated from various parts of the tropics, were identical either visually of spectrophotometrically when infected cell culture fluids were used as sources of antigen.
(11) In the Mahale Mountains National Park of Tanzania, a group of about 33 chimpanzees were observed to surround a leopard den containing a mother and at least one cub and to drag out and kill the cub.
(12) A series of temperature-sensitive (ts) mutants of dengue virus type 2 (DEN-2, TH-36 isolate) were induced by treatment with 5-azacytidine.
(13) produces more potential foci of tumour growth than in the normal liver and (2) that the repeated doses of CCl4 leading to repeated phases of regeneration, after the dose of DEN, provide a promoting stimulus.
(14) The shelf life of the solid phase presensitized with monoclonal antibodies was 4 mth at -15 degrees C. DEN prototype viruses were still identified after storage at -15 degrees C for 1 yr or at room temperature for 1 mth.
(15) O6EG levels in DNA of Clara cell-enriched populations were found to be higher than O6EG levels in DNA of alveolar type II cell-enriched populations and macrophages following acute DEN treatment.
(16) The fiber orientation is dependent on the height of dens axis, mostly in the cranial caudal direction.
(17) At earlier stages of the neoplastic process (11 or 16 weeks after the second DEN dose), most adenomas were well-differentiated lesions with no atypia or focal grade 1 or 2 atypia.
(18) This technique is best applied in nontraumatic cases in which the dens is not seen clearly on the "open mouth view".
(19) This treatment raised the number of adenosine-5'-triphosphatase (ATPase)-deficient foci up to 5-fold, that of gamma-glutamyltranspeptidase (GGTase) and glycogen-positive foci 13- and 10-fold, respectively, after 12 weeks; 25 mg caused no effect compared to DEN-treated controls.
(20) The system consists of a) single carcinogenic dose of diethylnitrosamine (DEN), b) short-term dietary exposure to 2-acetylaminofluorene (2-AAF) sufficient to suppress growth of virtually all normal hepatocytes, and c) partial hepatectomy (PH) to actuate rapid growth of DEN-altered hepatocytes not suppressed by 2-AAF.
Fen
Definition:
(n.) Low land overflowed, or covered wholly or partially with water, but producing sedge, coarse grasses, or other aquatic plants; boggy land; moor; marsh.
Example Sentences:
(1) Stereoselective degradation of fenoprofen (FEN) glucuronides and irreversible binding of FEN enantiomers to human serum albumin via their glucuronides were studied.
(2) In contrast, the chronotropic actions of ISO and FEN on atria from septic rats were mediated by what appears to be beta-2 receptors and those of PREN by beta-1 receptors.
(3) Macroscopic treatment-related liver enlargement (hepatomegaly) was observed in male and female rats fed 3000 or 10,000 ppm DC-FEN.
(4) One of the hybrids secretes a monoclonal antibody of the IgG3 subtype designated FEN-1, which reacts with 100% of endometrioid ovarian cancer containing adenoacanthoma by indirect immunoperoxidase on paraffin-embedded tissue.
(5) This study, probably the first detailed screening of the drug for its genotoxicity, shows that Fen is moderately clastogenic and a DNA damaging agent in vivo.
(6) Excreta energy (FE + UE), excreta nitrogen (FN + UN), and excreta energy corrected to zero nitrogen balance (FEn + UEn) losses were measured at 24-hr intervals as were body weights (BW) and weight losses (delta BW).
(7) In contrast, phencyclidine produced predominantly (greater than 50%) saline-appropriate responding, indicating that the DS effect of phencyclidine was unlike either AMPH or FEN.
(8) Concentrations of SAL, FEN, and FOR equivalent to 100 KD of the respective dissociation constants stimulated beta 2-adrenoceptor-coupled adenylate cyclase with different intrinsic activities (%) incomparison to ISO (SAL, 61%; FEN, 63%; FOR, 89%) matching intrinsic activities for relaxation.
(9) Chicks exposed as embryos to FEN were hyperactive and aggressive.
(10) In 16 children with steroid-responsive nephrotic syndrome (with minimal changes in the glomeruli) the plasma renin activity and aldosterone level were determined during recurrence of the nephrotic syndrome at the stage of oedema increase (FEN alpha 0.25%) and in early period of remission.
(11) Articles drafted by industry with minimal involvement from guest authors have been published in leading journals on hormone replacement therapy (HRT), Vioxx (an anti-inflammatory drug that was withdrawn amid safety fears), Neurontin (used in pain relief), antidepressants, and the combination diet drug, Fen-phen (also withdrawn for safety reasons).
(12) The concentrations of isoprenaline (56 nM) and fenoterol (165 nM) required to inhibit EFS (5 Hz) by 50% (IC50) were significantly less than those required to inhibit closely matched ACh responses to a comparable degree (ISO = 117 and FEN = 304 nM), and the maximum inhibition of EFS was greater.
(13) d-Fen caused an increase in absolute spleen weight and a decrease in absolute splenic cellularity only in the old rats of both sexes.
(14) Trichosanthin, an abortifacient, immunosuppressive and anti-tumor protein purified from the traditional Chinese herb medicine Tian Hua Fen, is a potent inhibitor against HIV-1 replication.
(15) The results suggest that 5-HT has a selective stimulatory effect on young male and old female NK activity, and that old female rats are more sensitive to the immunological effects of d-Fen than old male rats.
(16) Dose-dependent decreases in food intake were observed with AMPH being four times as potent as FEN.
(17) The percentage of S-FEN protein adduct was greater than that of its R-enantiomer adduct.
(18) Plasma oestradiol levels fluctuated in parallel with neuroendocrine responses to d-FEN.
(19) The supersensitivity to the chronotropic actions of ISO and FEN was much greater than that which developed to PREN.
(20) In order to examine the effect that ovarian steroids have on this response nine, healthy women were tested twice at three time points in the menstrual cycle: early follicular, mid-cycle and late luteal phase with either d-FEN, a more specific 5-HT agent than the racemic mixture, or placebo.