(v. t.) To render unnatural; to alienate from nature.
(v. t.) To renounce the natural rights and duties of; to deprive of citizenship; to denationalize.
Example Sentences:
(1) DNA in situ is progressively denatured when the cells or nuclei are treated with increasing concentration of acridine orange (AO).
(2) We propose that during the detergent solubilization the acidic phospholipids protect the transport systems against denaturation by preventing delipidation.
(3) Denaturation studies demonstrated that less than 50% of protein content of C. psittaci was denatured after 1 h of sonication, only 5% in the case of C. trachomatis.
(4) Our results also showed a good correlation between the importance of deposits and the presence of denatured DNA-anti-denatured-DNA circulating complexes.
(5) Refolding was observed by injection of denatured protein into columns having isocratic concentrations in the transition and native base-line zones.
(6) Extraction of liposomes containing guanylate cyclase with 0.2% Lubrol PX resulted in the recovery of 85% of the original amount of added activity, suggesting that the decrease in maximal velocity was not due to enzyme denaturation.
(7) Single-stranded circles did not form if a limited number of nucleotides were removed from the 3' ends of native molecules by Escherichia coli exonuclease III digestion prior to denaturation and annealing.
(8) Denatured DNA and histones were inhibitory, but native DNA and its histone complex were not inhibitory.
(9) Both enzymes are capable of catalyzing the refolding of thermally denatured type III collagen.
(10) We investigated the denaturation of tetrameric 20 beta-hydroxysteroid dehydrogenase (20R)-17 beta,20 beta,21-trihydroxysteroid:NAD+ oxidoreductase, EC 1.1.1.53) to find out whether intermediate states are formed during the process.
(11) Thermal-denaturation studies showed that this bromoperoxidase could tolerate high temperatures.
(12) Pig kidney extracts have been partially purified by thermal denaturation and chromatography on Sephadex G-200 and D.E.A.E.
(13) RNA transcribed by RNA polymerase II on denatured DNA was only large RNA around 28S.
(14) The differential scanning calorimetry (DSC) studies demonstrate an increased susceptibility of the Ala 183----Pro mutant to thermal denaturation.
(15) The secreted antibody, which can be readily purified from the media without any denaturation or renaturation steps, retains antigen-binding activity.
(16) The electrophoretic pattern of free radical-exposed FABP was not markedly different when examined either by the non-denaturing or by denaturing PAGE, suggesting the absence of any degradation or aggregation of FABP by O2- or OH..
(17) Synthesis with denatured DNA as template presumably proceeds from 3'-hydroxyl termini formed at loop-back regions since the synthesized DNA product and template are covalently linked.
(18) Multiple contacts between the gamma-subunit and calmodulin (delta-subunit), as indicated by our data, may help to explain why strongly denaturing conditions are required to dissociate these two subunits, whereas complexes of calmodulin with most other target enzymes can be readily dissociated by merely lowering Ca2+ to submicromolar concentrations.
(19) Heating is shown to bring about only the denaturation of protein molecules in crystals.
(20) Renal tissues from two groups of patients were studied with fluorescein-labeled (Fl-) antibodies (Abs) to immunoglobulins, complement, and antibodies prepared in rabbits against BSA conjugate of 5-methyluridine (T) and cytidine (C), the latter two of which react specifically with denatured DNA.
Deny
Definition:
(v. t.) To declare not to be true; to gainsay; to contradict; -- opposed to affirm, allow, or admit.
(v. t.) To refuse (to do something or to accept something); to reject; to decline; to renounce.
(v. t.) To refuse to grant; to withhold; to refuse to gratify or yield to; as, to deny a request.
(v. t.) To disclaim connection with, responsibility for, and the like; to refuse to acknowledge; to disown; to abjure; to disavow.
(v. i.) To answer in /// negative; to declare an assertion not to be true.
Example Sentences:
(1) He still denied it and said he was giving the girl a lift.
(2) The highest rate of discontinuation occurred when method choice was denied in the presence of husband-wife agreement on method choice, and the lowest rate occurred when method choice was granted in the presence of such concurrence.
(3) It was with unanimous consent.” He denied that Trump’s tweets had played a part, saying: “No, no, no.
(4) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(5) Keep it in the ground campaign Though they draw on completely different archives, leaked documents, and interviews with ex-employees, they reach the same damning conclusion: Exxon knew all that there was to know about climate change decades ago, and instead of alerting the rest of us denied the science and obstructed the politics of global warming.
(6) Greek officials categorically denied the report with many describing it as a "joke".
(7) In practice they are so elastic that they have been used to deny pasta to besieged Gazans.
(8) It felt like my very existence was being denied,” said Hahn Chae-yoon, executive director of Beyond the Rainbow Foundation.
(9) The government has blamed a clumsily worded press release for the furore, denying there would be random checks of the public.
(10) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(11) Both of these bills include restrictions on moving terrorists into our country.” The White House quickly confirmed the president would have to sign the legislation but denied this meant that its upcoming plan for closing Guantánamo was, in the words of one reporter, “dead on arrival”.
(12) However ITV deny that any approach or offer, formal or informal, has been made.
(13) To organise society as an individualistic war of one against another was barbaric, while the other models, slavishly following the rules of one religion or one supreme leader, denied freedom.
(14) He denied that the probation service budget, which has been protected so far from 23% cuts, would be a particular target, but said it was not yet making the same level of savings as was being required of the police.
(15) Nepalese workers building stadiums for the 2022 World Cup in Qatar have been denied leave to attend funerals or visit relatives following the earthquakes in the Himalayan country that have killed more than 8,000 people, its government has revealed.
(16) Authorities in most cities – from Chita in Siberia to Makhachkala in Dagestan – denied permission for the rallies.
(17) Planned Parenthood denies the accusations, saying it donates fetal tissue to medical research companies at no cost.
(18) However, a spokesperson for the Department for Communities and Local Government denied any reports of a rift with the Treasury.
(19) There were numerous reports of looting and tampering with evidence, although rebel authorities angrily denied them.
(20) It could bring down the prime minister, though he denies it.