(a.) Having the constituent parts massed or crowded together; close; compact; thick; containing much matter in a small space; heavy; opaque; as, a dense crowd; a dense forest; a dense fog.
(a.) Stupid; gross; crass; as, dense ignorance.
Example Sentences:
(1) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(2) In spite of dense lymphocytic infiltration only 3% of the tumor infiltrating lymphocytes exhibit the activation marker CD 25.
(3) Immunogold electron microscopy demonstrated that outer dense fibres were the predominant immunoreactive site.
(4) Electron microscopy revealed the presence of a hitherto unreported peculiar "pilovacuolar" inclusion in numerous mitochondria, composed of an electron dense pile or rod within a vacuole, while globular or crystalline inclusions were absent.
(5) A recent report suggested that neurons in the prefrontal, anterior cingulate, and primary motor cortex of the brains of schizophrenic subjects may be less dense than those in the brains of nonschizophrenic subjects.
(6) Two years ago, the Intergovernmental Panel on Climate Change declared Egypt's Nile Delta to be among the top three areas on the planet most vulnerable to a rise in sea levels, and even the most optimistic predictions of global temperature increase will still displace millions of Egyptians from one of the most densely populated regions on earth.
(7) Chick sympathetic nerve fibers densely innervate expansor secundariorum muscle, but not skeletal muscle.
(8) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(9) In the first assay, we used a simple density separation technique to remove dense neutrophils (PMN) from suspensions of blood and of bone marrow cells prior to culture in semisolid agar.
(10) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(11) The outstanding morphologic feature of cortical cells exposed to microunit ACTH concentrations for 40 min was the abundance of electron-dense granules (0.2-0.4 mum).
(12) The majority of intensively stained and densely packed cells have been observed in tv nucleus.
(13) The wall of the yolk sac thickens as a result of this infolding and the densely packed capillaries.
(14) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(15) Martin O’Neill spoke of his satisfaction at the Republic of Ireland’s score draw in the first leg of their Euro 2016 play-off against Bosnia-Herzegovina – and of his relief that the match was not abandoned despite the dense fog that descended in the second half and threatened to turn the game into a farce.
(16) Phagosomes and dense bodies reminiscent of Russel bodies also occurred in the Mikulicz cells, in the vacuoles of which formations representing Klebsiella rhinoscleromatis were demonstrated.
(17) Electron microscopic examination of all leptomeningeal and meningioma cultures revealed desmosomes and dense tonofilament formation; in addition, granular, filamentous basement membrane-like material was abundant in the extracellular spaces of all cultures.
(18) Genes of the baker's yeast Saccharomyces cerevisiae are densely clustered on 16 linear chromosomes.
(19) The results suggest that the conversion of the HRP-TMB reaction product to an electron-dense form during osmication is intimately associated with the pH of the phosphate buffer and the total time of osmication.
(20) Chemical binding studies showed that the teichoic acid was the major uranyl binding component in isolated walls, from which it might be inferred that teichoic acid was located in the densely staining regions.
Heavy
Definition:
(a.) Having the heaves.
(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.