(a.) To empty or unload, as the vessels of human system, by bloodletting or by medicine.
(a.) To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc.
Example Sentences:
(1) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(2) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(3) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(4) Male weanling Sprague Dawley rats were depleted on a low AIN-76A formulated basal diet for 21 days.
(5) The reduction rates of peripheral leukocytes, lung Schiff bases and lung water content were not identical in rats depleted from leukocyte after inhalation injury.
(6) E-RFC enriched for T lymphocytes and depleted of macrophages synthesized considerable DNA in response to stimulation with PHA, but were unable to produce significant bone resorbing activity in tissue culture unless macrophages were re-added to the E-RFC.
(7) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(8) Upon depletion of ATP in contraction, the P2 intensity reverted to the original rigor level, accompanied by development of rigor tension.
(9) Photolysis of the photosystem I particles induces a progressive depletion of phylloquinone, however, photochemistry as assayed at room temperature by the photooxidation of P-700 is unaffected.
(10) It is suggested that the cause of this inhibition resides in depletion of the NADPH pool due to the high rate at which NADPH is oxidized by 2-ketogluconate reductase.
(11) They disappear after Leydig cell depletion induced by ethanedimethane sulphonate (EDS) and return after testosterone treatment.
(12) Accordingly, we repleted vitamin D-depleted rats with subcutaneous injections of 2600, 520, and 130 pmoles of cholecalciferol (D3), 25-hydroxycholecalciferol (25(OH)D3), and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), respectively, for up to 3 weeks.
(13) The results suggest that in sodium-depleted rats denervation natriuresis can be ascribed neither to strain differences nor to the high sucrose content of the low-sodium diet.
(14) ACTH and dcAMP affect depletion of endogenously labeled ascorbic acid in IAC by a process that is both concentration- and time-dependent, but is independent of steroidogenic processes.
(16) Extracellular Na+ depletion promptly decreased [Na+]i from 15.8 to 5.4 mM (P less than 0.01), which was closely related to the decrease in pHi (7.19 to 6.97; P less than 0.01).
(17) The latter phase of depletion was associated with a decrease in synaptosomal [3H]serotonin uptake due to a loss in the number of uptake sites with no change in the affinity of the carrier for serotonin.
(18) Depletion of extracellular Ca2+ by EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N'N'-tetraacetic acid] attenuated both [Ca2+]i increase and superoxide production induced by particles.
(19) The resistance of N50-4 cells to CLB was almost completely abolished by combination pretreatment yielding both GSH depletion and GST inhibition.
(20) Cysteamine pretreatment of rats (depletion of somatostatin containing D-cells and decrease in somatostatin secretion) did not change the Met-enkephalin effect on insulin secretion.
Diminish
Definition:
(v. t.) To make smaller in any manner; to reduce in bulk or amount; to lessen; -- opposed to augment or increase.
(v. t.) To lessen the authority or dignity of; to put down; to degrade; to abase; to weaken.
(v. t.) To make smaller by a half step; to make (an interval) less than minor; as, a diminished seventh.
(v. t.) To take away; to subtract.
(v. i.) To become or appear less or smaller; to lessen; as, the apparent size of an object diminishes as we recede from it.
Example Sentences:
(1) Diminished CMD was most common with AR (7 of 12) but was also seen with acute tubular necrosis (2 of 6) and cyclosporin toxicity (2 of 3).
(2) If women psychiatrists are to fill some of the positions in Departments of Psychiatry, which will fall vacant over the next decade, much more attention must be paid to eliminating or diminishing the multiple obstacles for women who chose a career in academic psychiatry.
(3) The results indicated that the role of contact inhibition phenomena in arresting cellular proliferation was diminished in perfusion system environments.
(4) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(5) Virus replication in nasal turbinates was not diminished while infection in the lung was suppressed sufficiently for the infected mice to survive the infection.
(6) The last stems from trends such as declining birth rate, an increasingly mobile society, diminished importance of the nuclear family, and the diminishing attractiveness of professions involved with providing maintenance care.
(7) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(8) In addition, the activity of the large cells diminished with time after primary immunization, but that of the small cells remained stable.
(9) The antibody reacted with adult as well as with cord red cells, and its reactivity was strongly diminished by treatment of the cells with neuraminidase and to a lesser degree by treatment with protease.
(10) The concomitant reduction in aortic pressure and increase in heart rate following total occlusion of the portal vein were most pronounced during the first weeks after stenosis, and were probably due to diminished venous return to the heart.
(11) Conversely, the latter diminished basal plasma glucose levels.
(12) Subsequently, the inflammatory reaction diminishes, as can be seen on smears from tympanic effusions.
(13) Both Apo AI (48%) and Apo AII (5.5%) were greatly diminished and Apo E was present in remarkably high amounts (39%) with two additional isoforms (Apo E'1 and Apo E'2).
(14) (3) The diminished autophosphorylation rate was due to a decreased responsiveness of the kinase activity to the action of insulin.
(15) The isoenzyme mobility diminished in both tumour chromatin extracts, and the slow migrating gamma isoenzyme exhibited sensitivity to L-cysteine inhibition.
(16) Segmental function was diminished an average of 67.8% in "noses" and 46.6% in "bridges".
(17) Flexion of the knee beyond 40 degrees progressively diminished viability of the edges of the wound, particularly the lateral edge.
(18) EEG waves were similar during Aw and Qw but they diminished in amplitude and frequency when passing from these states to Qs, and both parameters increased during As.
(19) After 3-5 days of side-arm traction, swelling had usually diminished sufficiently to allow the elbow to be safely hyperflexed to stabilize the fracture after elective closed reduction.
(20) In the patients with aplastic anaemia the iron flux was diminished, but never eliminated, demonstrating that the exchangeable compartment was not solely erythroblastic, but included non-erythroid transferrin receptors.