(a.) To empty or unload, as the vessels of human system, by bloodletting or by medicine.
(a.) To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc.
Example Sentences:
(1) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(2) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(3) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(4) Male weanling Sprague Dawley rats were depleted on a low AIN-76A formulated basal diet for 21 days.
(5) The reduction rates of peripheral leukocytes, lung Schiff bases and lung water content were not identical in rats depleted from leukocyte after inhalation injury.
(6) E-RFC enriched for T lymphocytes and depleted of macrophages synthesized considerable DNA in response to stimulation with PHA, but were unable to produce significant bone resorbing activity in tissue culture unless macrophages were re-added to the E-RFC.
(7) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(8) Upon depletion of ATP in contraction, the P2 intensity reverted to the original rigor level, accompanied by development of rigor tension.
(9) Photolysis of the photosystem I particles induces a progressive depletion of phylloquinone, however, photochemistry as assayed at room temperature by the photooxidation of P-700 is unaffected.
(10) It is suggested that the cause of this inhibition resides in depletion of the NADPH pool due to the high rate at which NADPH is oxidized by 2-ketogluconate reductase.
(11) They disappear after Leydig cell depletion induced by ethanedimethane sulphonate (EDS) and return after testosterone treatment.
(12) Accordingly, we repleted vitamin D-depleted rats with subcutaneous injections of 2600, 520, and 130 pmoles of cholecalciferol (D3), 25-hydroxycholecalciferol (25(OH)D3), and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), respectively, for up to 3 weeks.
(13) The results suggest that in sodium-depleted rats denervation natriuresis can be ascribed neither to strain differences nor to the high sucrose content of the low-sodium diet.
(14) ACTH and dcAMP affect depletion of endogenously labeled ascorbic acid in IAC by a process that is both concentration- and time-dependent, but is independent of steroidogenic processes.
(16) Extracellular Na+ depletion promptly decreased [Na+]i from 15.8 to 5.4 mM (P less than 0.01), which was closely related to the decrease in pHi (7.19 to 6.97; P less than 0.01).
(17) The latter phase of depletion was associated with a decrease in synaptosomal [3H]serotonin uptake due to a loss in the number of uptake sites with no change in the affinity of the carrier for serotonin.
(18) Depletion of extracellular Ca2+ by EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N'N'-tetraacetic acid] attenuated both [Ca2+]i increase and superoxide production induced by particles.
(19) The resistance of N50-4 cells to CLB was almost completely abolished by combination pretreatment yielding both GSH depletion and GST inhibition.
(20) Cysteamine pretreatment of rats (depletion of somatostatin containing D-cells and decrease in somatostatin secretion) did not change the Met-enkephalin effect on insulin secretion.
Mitigate
Definition:
(v. t.) To make less severe, intense, harsh, rigorous, painful, etc.; to soften; to meliorate; to alleviate; to diminish; to lessen; as, to mitigate heat or cold; to mitigate grief.
(v. t.) To make mild and accessible; to mollify; -- applied to persons.
Example Sentences:
(1) In mitigation, Gareth Jones, defending, said: "The first comment [he] wrote was in relation to Fabrice Muamba.
(2) The small numbers involved (29) and the difficulties in matching subjects may have mitigated against demonstrating a statistically significant difference between the two groups.
(3) The news comes one week after Marshall announced, in an email to staff, that there would be a shift in research priorities, away from understanding the nature of climate change, and towards adaptation and mitigation.
(4) Golding said the government would not soften its stance on drug trafficking and it intended to use a proportion of revenues from its licensing authority to support a public education campaign to discourage pot-smoking by young people and mitigate public health consequences.
(5) This has improved the capacity of the neuroanaesthetist to mitigate the inevitable fluctuations which occur and prevent their ill effects.
(6) The survey was designed to assess whether these individuals followed the 1986 EPA guidelines for follow-up testing and mitigation.
(7) Despite doing a study of mitigation options, no decisions are planned until 2012.
(8) The level of disruption to services will vary widely and depend on the number of staff joining the strike, the mitigating impact of the NHS’s contingency planning and how many patients need acute care, such as A&E care or surgery.
(9) Aid workers have warned that children in the disaster zone left by typhoon Haiyan are particularly vulnerable, as they set up child-focused services to mitigate the impact.
(10) Regression analyses suggested that such aggression-inhibitory effects of an apology were mediated by impression improvement, emotional mitigation, and reduction in desire for an apology within the victims.
(11) At present, however, technical and economic factors combine to mitigate against MRI.
(12) The IPCC is charged with providing a scientific, balanced assessment about what's known and what's known about climate change There are lots of organisations ringing bells The IPCC is more like a belltower, which people can climb up to get a clear view 8.41am BST Al Gore , the former US vice-president and winner of the Nobel peace prize for his work on climate change , has responded to the IPCC report by saying it shows the need for a switch to low carbon sources of energy (note his emphasis is on mitigation, i.e.
(13) Potential strategies to avoid the precipitating antigen antibody reaction or to mitigate the resulting effector cascade are described.
(14) The results of this study serve to mitigate concern over the possible carcinogenicity of MDA in the diet, since less than 10% of the MDA in several foods containing highly unsaturated fatty acids was found in the free form.
(15) The deputy president, William Ruto, said it is now up to the developed world to mitigate the fallout, suggesting that other countries including the UK should resettle the refugees who could soon be kicked out of Kenya.
(16) Application of the formula in 3 patients with the juvenile CLF, the M. Batten-Spielmeyer-Vogt, resulted in a mitigated course of the disease.
(17) "The one thing that we have come up with is the importance of adaptation and mitigation choices.
(18) There is an art as well as a science to accurately presenting devastating facts while mitigating potentially unnecessary emotional damage.
(19) The issue is the capacity of the law to mitigate it.
(20) Delivery of oxygenated autologous blood to the myocardium at risk during inflation may help mitigate this ischemia.