(a.) To empty or unload, as the vessels of human system, by bloodletting or by medicine.
(a.) To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc.
Example Sentences:
(1) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(2) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(3) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(4) Male weanling Sprague Dawley rats were depleted on a low AIN-76A formulated basal diet for 21 days.
(5) The reduction rates of peripheral leukocytes, lung Schiff bases and lung water content were not identical in rats depleted from leukocyte after inhalation injury.
(6) E-RFC enriched for T lymphocytes and depleted of macrophages synthesized considerable DNA in response to stimulation with PHA, but were unable to produce significant bone resorbing activity in tissue culture unless macrophages were re-added to the E-RFC.
(7) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(8) Upon depletion of ATP in contraction, the P2 intensity reverted to the original rigor level, accompanied by development of rigor tension.
(9) Photolysis of the photosystem I particles induces a progressive depletion of phylloquinone, however, photochemistry as assayed at room temperature by the photooxidation of P-700 is unaffected.
(10) It is suggested that the cause of this inhibition resides in depletion of the NADPH pool due to the high rate at which NADPH is oxidized by 2-ketogluconate reductase.
(11) They disappear after Leydig cell depletion induced by ethanedimethane sulphonate (EDS) and return after testosterone treatment.
(12) Accordingly, we repleted vitamin D-depleted rats with subcutaneous injections of 2600, 520, and 130 pmoles of cholecalciferol (D3), 25-hydroxycholecalciferol (25(OH)D3), and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), respectively, for up to 3 weeks.
(13) The results suggest that in sodium-depleted rats denervation natriuresis can be ascribed neither to strain differences nor to the high sucrose content of the low-sodium diet.
(14) ACTH and dcAMP affect depletion of endogenously labeled ascorbic acid in IAC by a process that is both concentration- and time-dependent, but is independent of steroidogenic processes.
(16) Extracellular Na+ depletion promptly decreased [Na+]i from 15.8 to 5.4 mM (P less than 0.01), which was closely related to the decrease in pHi (7.19 to 6.97; P less than 0.01).
(17) The latter phase of depletion was associated with a decrease in synaptosomal [3H]serotonin uptake due to a loss in the number of uptake sites with no change in the affinity of the carrier for serotonin.
(18) Depletion of extracellular Ca2+ by EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N'N'-tetraacetic acid] attenuated both [Ca2+]i increase and superoxide production induced by particles.
(19) The resistance of N50-4 cells to CLB was almost completely abolished by combination pretreatment yielding both GSH depletion and GST inhibition.
(20) Cysteamine pretreatment of rats (depletion of somatostatin containing D-cells and decrease in somatostatin secretion) did not change the Met-enkephalin effect on insulin secretion.
Tired
Definition:
(imp. & p. p.) of Tire
(a.) Weary; fatigued; exhausted.
Example Sentences:
(1) As he sits in Athens wondering when the International Monetary Fund is going to deliver another bailout, George Papandreou might be tempted to hum a few lines of Tired of Waiting for You.
(2) I was so tired I just used to fall asleep on my feet.
(3) According to articles presented by Breitbart, Clinton is tired and ailing.
(4) That may sound familiar to Tottenham fans, who grew tired with their team’s aimless, sideways passing under André Villas-Boas.
(5) I’m personally sick and tired of Pristina and Belgrade, because we’ve been victimised by high politicians.” Facebook Twitter Pinterest The bridge connecting the Albanian and Serb parts of Mitrovica.
(6) An example calculation of rolling resistance for a polyurethane tire is given in detail.
(7) The extent of inadequate rest has prompted fears that many people are too tired to do their jobs properly, with some so sleep-deprived their brains are as confused as if they had consumed too much alcohol.
(8) Do you not get tired of the mass surveillance in this country?” Finicum told reporters.
(9) We’re tired of answering these questions,” one woman said.
(10) I’m tired, man.” But he hopes that it might be done quickly.
(11) I, along with many others, am tired of this toxic propaganda.
(12) Further the diabetics claimed to be more tired and diabetic males had more sexual concerns.
(13) Apart from that, it’s becoming increasingly tiring to see people posing about how there is no point voting because it’s all rigged, the politicians are all the same and the rest.
(14) In any case, people had tired of combative rhetoric and wanted softer platitudes.
(15) There is no guarantee of surgical success with such an injury but Murray was tiring of the constant reliance on pain killers to get through tough matches.
(16) The concentrations of 1-NP and airborne particulates changed significantly in all examined areas in parallel with the rise and fall of the frequencies of studded tire use.
(17) Transposable and interspersed repetitive elements (TIREs) are ubiquitous features of both prokaryotic and eukaryotic genomes.
(18) The players come to Australia tired and exhausted already because they’ve been going since mid-November.” Another issue is the way the women treat their practice time.
(19) But when you're tired, you've played in 94 or 95 minutes, players choose power rather than technique, rather than placing it.
(20) On the return journey, the tired passengers exchange smuggling anecdotes and safety tips.