What's the difference between deposit and tophus?

Deposit


Definition:

  • (n.) To lay down; to place; to put; to let fall or throw down (as sediment); as, a crocodile deposits her eggs in the sand; the waters deposited a rich alluvium.
  • (n.) To lay up or away for safe keeping; to put up; to store; as, to deposit goods in a warehouse.
  • (n.) To lodge in some one's hands for safe keeping; to commit to the custody of another; to intrust; esp., to place in a bank, as a sum of money subject to order.
  • (n.) To lay aside; to rid one's self of.
  • (v. t.) That which is deposited, or laid or thrown down; as, a deposit in a flue; especially, matter precipitated from a solution (as the siliceous deposits of hot springs), or that which is mechanically deposited (as the mud, gravel, etc., deposits of a river).
  • (v. t.) A natural occurrence of a useful mineral under the conditions to invite exploitation.
  • (v. t.) That which is placed anywhere, or in any one's hands, for safe keeping; something intrusted to the care of another; esp., money lodged with a bank or banker, subject to order; anything given as pledge or security.
  • (v. t.) A bailment of money or goods to be kept gratuitously for the bailor.
  • (v. t.) Money lodged with a party as earnest or security for the performance of a duty assumed by the person depositing.
  • (v. t.) A place of deposit; a depository.

Example Sentences:

  • (1) The Cavitron Ultrasonic Surgical Aspirator (CUSA) is a dissecting system that removes tissue by vibration, irrigation and suction; fluid and particulate matter from tumors are aspirated and subsquently deposited in a canister.
  • (2) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
  • (3) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
  • (4) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
  • (5) The kidney disease was characterized by diffuse beaded deposition of rat gammaglobulin along the glomerular capillaries and proteinuria.
  • (6) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
  • (7) A comprehensive review of the roentgenographic features of calcium pyrophosphate crystal deposition disease (pseudogout) is presented.
  • (8) We conclude that heparin plus AT III partially prevents the endotoxin-induced generation of PAI activity which seems to correlate with the reduced presence of fibrin deposits in kidneys and with a reduced mortality.
  • (9) These results suggest that glomerular IgA are IgA polymers and decreased hepatic clearance of hepatic IgA polymers may be responsible for the glomerular deposition of IgA.
  • (10) The organisms were predominantly associated with host deposits of erythrocytes, phagocytes, platelets, and fibrinous-appearing material, which collectively appeared on the valve surface in response to trauma.
  • (11) Our results also showed a good correlation between the importance of deposits and the presence of denatured DNA-anti-denatured-DNA circulating complexes.
  • (12) It is not known whether the deposits are primary or secondary events, but they may be of importance in initiating or maintaining derangement in heart function.
  • (13) The aim of the trial was to determine the effectiveness of aspirin in preventing cardiovascular problems in people with asymptomatic atherosclerosis – the undetected build-up of waxy plaque deposits on the inside of blood vessels.
  • (14) The hypothesis was tested that plaque, as a complex soil comprising microorganisms, cell debris, salivary deposits and other ill-defined organic and inorganic components, would be susceptible to removal by a rinse with high detersive action.
  • (15) The monoclonal antibody K2F6 fails to react with water-soluble proteins from fat body and hemolymph taken during the deposition of the 20-kDa antigen.
  • (16) Alveolar deposition, however, assessed in terms of particle retention at 24 hours, was significantly (p less than 0.01) less in the smokers.
  • (17) The blockage of the tubular system by the calcium oxalate deposits leads to a temporary reversible increase in serum urea and serum creatinine.
  • (18) In the six cases of aortic aneurysm, three had platelet deposition within their aneurysms, and surgery was performed for these positive cases, but one of them had no thrombus.
  • (19) Initial deposition was about 1,200 Bq (32 nCi) for 239PuO2, 4,200 Bq (115 nCi) for 244Cm, and 2,400 Bq (65 nCi) total alpha for the mixed oxide.
  • (20) From the morphological observations there seems to be no correlation between amyloid deposits and the development of osteoarthrosis.

Tophus


Definition:

  • (n.) One of the mineral concretions about the joints, and in other situations, occurring chiefly in gouty persons. They consist usually of urate of sodium; when occurring in the internal organs they are also composed of phosphate of calcium.
  • (n.) Calcareous tufa.

Example Sentences:

  • (1) Seven-to-14-week-old pullets from this facility had multifocal renal tubular necrosis leading to interstitial fibrosis, tophus formation, and tubular dilation.
  • (2) A rare case of gouty tophus localized to the temporomandibular joint is reported on by which alimentary troubles were caused.
  • (3) After 1 month, the kidneys showed the previously described histologic features of urate-blockade nephropathy characterized by intratubular deposits, tubular injury, and an exudative response consisting of neutrophilic granulocytes with early tophus formation.
  • (4) The authors report a rare case of tophus situated in the optic nerve and coexisting with aneurysm of the anterior communicating artery.
  • (5) We describe an elderly woman presenting acutely with tophus formation mimicking infection, in whom diuretic therapy was responsible for her disease.
  • (6) Almost all the sites of tophus-like deposits of CPPD crystals and the degenerated matrix containing low concentrations of scattered CPPD crystals stained strongly with Sudan III.
  • (7) In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona.
  • (8) Tophus formation at the temporomandibular joint with extension into the fossa infratemporalis has been mentioned only three times in the world literature.
  • (9) A case of extradural gouty tophus in the lumbar region in a teen-age girl is presented as an addition to the differential diagnosis of erosive lesions of the spinal canal.
  • (10) Both tophus-derived and synthetic crystals appeared to be weak hemolytic agents.
  • (11) Endoscopic biopsy revealed a tophus of the true vocal cord with characteristic birefringent crystalline deposits and giant cell granuloma.
  • (12) Monosodium urate monohydrate (MSUM) crystals derived from a tophus surgically removed from patients suffering from gout and MSUM prepared from a supersaturated solution of sodium urate were studied and compared with respect to their ability to: (1) stimulate chemiluminescence (CL) production by human polymorphonuclear (PMN) cells, (2) induce hemolysis of the human red blood cells and (3) induce inflammation when injected in the rat paw and knee joint.
  • (13) -In the present paper, the authors report on the extraordinary location of an urate tophus in the fossa infratemporalis - in this case, there was even destruction of the middle base of the skull - which had been misinterpreted for years, having been diagnosed as a primary disease of the parotid gland.
  • (14) A burn precipitated one bulla, showing that local tissue injury can be a factor in tophus localization.
  • (15) Subcutaneous cholesterol crystal deposition with tophus formation is extremely rare and has been described in a patient with scleroderma and calcinosis cutis.
  • (16) The findings suggest that acini of macrophages are formed and that active cellular transport of urate from the interstitial fluid into the central zones of these structures accounts for the focal nature of crystallization within the tophus.
  • (17) A typical gouty tophus with birefringent, dichroic, needle shaped crystals was found in a resected calcified aortic valve on routine histological examination.
  • (18) Fresh tophaceous material from a patient with gout contained significant levels of TNF alpha and cells cultured from the tophus produced TNF alpha in vitro.
  • (19) Evidence of an axial skeletal tophus causing an irritative radiculopathy via mass effect is presented.
  • (20) Each of those formulations of a pathogenetic role for crystals may be true in a given case, analogous to the etiology of primary and secondary forms of hyperuricemia and to sodium urate crystal deposition coexistent with osteoarthritis (tophus formation in Heberden's nodes).

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