(n.) An agent or remedy which lowers the vital powers.
Example Sentences:
(1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
(2) Thyroid replacement led to resolution of both apnea and depression.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(5) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
(6) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(7) The ED50 and ED95 of mivacurium in each group were estimated from linear regression plots of log dose vs probit of maximum percentage depression of neuromuscular function.
(8) The data are compared with the results from 79 patients with a bipolar depression, 192 with a neurotic depression and 89 with a depressive reaction.
(9) A similar depressed receptor function was observed for C3b, fibronectin, and some lectins.
(10) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(11) Both treatments depressed nocturnal pineal melatonin content in rats and hamsters.
(12) Infusion of sodium lactate associated with isoproterenol could be used to combat the depressent effects of betablockers in patients with cardiac disorders.
(13) We studied the effects of the localisation and size of ischemic brain infarcts and the influence of potential covariates (gender, age, time since infarction, physical handicap, cognitive impairment, aphasia, cortical atrophy and ventricular size) on 'post-stroke depression'.
(14) The literature on depression and immunity is reviewed and the clinical implications of our findings are discussed.
(15) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(16) However, a recrudescence in both psychotic and depressive symptoms developed as plasma desipramine levels rose 4 times higher than anticipated from the oral doses prescribed.
(17) These results indicate that the hormonal status should be taken into consideration in studies dealing with platelet MAO activity in depressed women.
(18) Three coyotes were operantly conditioned to depress one of two foot treadles, left or right, depending on the condition of the stimulus light.
(19) Although esmolol may be used as a primary hypotensive agent, the potential for marked myocardial depression must be recognized.
(20) Subjects who reported incidents of childhood sexual exploitation had lower levels of self-esteem and higher levels of depression than the comparison group.
Substance
Definition:
(n.) That which underlies all outward manifestations; substratum; the permanent subject or cause of phenomena, whether material or spiritual; that in which properties inhere; that which is real, in distinction from that which is apparent; the abiding part of any existence, in distinction from any accident; that which constitutes anything what it is; real or existing essence.
(n.) The most important element in any existence; the characteristic and essential components of anything; the main part; essential import; purport.
(n.) Body; matter; material of which a thing is made; hence, substantiality; solidity; firmness; as, the substance of which a garment is made; some textile fabrics have little substance.
(n.) Material possessions; estate; property; resources.
(n.) Same as Hypostasis, 2.
(v. t.) To furnish or endow with substance; to supply property to; to make rich.
Example Sentences:
(1) No differences between the two substances were observed with respect to side effects and general tolerability.
(2) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(3) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(4) Intracellular localization of the labeled substance in the tumor tissue was examined autohistoradiographically.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(8) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(9) Urine tests in six patients with other kidney diseases and with uraemia and in seven healthy persons did not show this substance.
(10) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(11) Regulators concerned about physician behavior and confronted by demands of nonphysicians to prescribe controlled substances may find EDT a good solution.
(12) These results are discussed in the light of the mode of action of the substances used.
(13) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(14) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.
(15) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(16) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
(17) They were more irregularly curved and consisted of various substances.
(18) We examined 10 life areas clustered around the general categories of "substance use," "social functioning," and "emotional and interpersonal functioning."
(19) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(20) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.