What's the difference between depression and lacuna?

Depression


Definition:

  • (n.) The act of depressing.
  • (n.) The state of being depressed; a sinking.
  • (n.) A falling in of the surface; a sinking below its true place; a cavity or hollow; as, roughness consists in little protuberances and depressions.
  • (n.) Humiliation; abasement, as of pride.
  • (n.) Dejection; despondency; lowness.
  • (n.) Diminution, as of trade, etc.; inactivity; dullness.
  • (n.) The angular distance of a celestial object below the horizon.
  • (n.) The operation of reducing to a lower degree; -- said of equations.
  • (n.) A method of operating for cataract; couching. See Couch, v. t., 8.

Example Sentences:

  • (1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
  • (2) Thyroid replacement led to resolution of both apnea and depression.
  • (3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
  • (4) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
  • (5) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
  • (6) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
  • (7) The ED50 and ED95 of mivacurium in each group were estimated from linear regression plots of log dose vs probit of maximum percentage depression of neuromuscular function.
  • (8) The data are compared with the results from 79 patients with a bipolar depression, 192 with a neurotic depression and 89 with a depressive reaction.
  • (9) A similar depressed receptor function was observed for C3b, fibronectin, and some lectins.
  • (10) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
  • (11) Both treatments depressed nocturnal pineal melatonin content in rats and hamsters.
  • (12) Infusion of sodium lactate associated with isoproterenol could be used to combat the depressent effects of betablockers in patients with cardiac disorders.
  • (13) We studied the effects of the localisation and size of ischemic brain infarcts and the influence of potential covariates (gender, age, time since infarction, physical handicap, cognitive impairment, aphasia, cortical atrophy and ventricular size) on 'post-stroke depression'.
  • (14) The literature on depression and immunity is reviewed and the clinical implications of our findings are discussed.
  • (15) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
  • (16) However, a recrudescence in both psychotic and depressive symptoms developed as plasma desipramine levels rose 4 times higher than anticipated from the oral doses prescribed.
  • (17) These results indicate that the hormonal status should be taken into consideration in studies dealing with platelet MAO activity in depressed women.
  • (18) Three coyotes were operantly conditioned to depress one of two foot treadles, left or right, depending on the condition of the stimulus light.
  • (19) Although esmolol may be used as a primary hypotensive agent, the potential for marked myocardial depression must be recognized.
  • (20) Subjects who reported incidents of childhood sexual exploitation had lower levels of self-esteem and higher levels of depression than the comparison group.

Lacuna


Definition:

  • (n.) A small opening; a small pit or depression; a small blank space; a gap or vacancy; a hiatus.
  • (n.) A small opening; a small depression or cavity; a space, as a vacant space between the cells of plants, or one of the spaces left among the tissues of the lower animals, which serve in place of vessels for the circulation of the body fluids, or the cavity or sac, usually of very small size, in a mucous membrane.

Example Sentences:

  • (1) Casts of lacunae and canaliculi along with the underlying matrix could be visualized in these preparations.
  • (2) This kind of distribution of microfilaments was always associated with resorption lacunae, and F-actin, vinculin, and talin zones correspond roughly to the edge of lacunae.
  • (3) As lacunae develop, both syncytial and cytotrophoblast are exposed to maternal blood.
  • (4) A cartilage is regarded as 'cell-rich' if its cells or their lacunae occupy more than half of the tissue volume.
  • (5) Intravenous urography reveals the presence of a persistent lacuna in a calix or of the pelvis, radiologic evidence of the abnormal papilla.
  • (6) Under the scanning electron microscope, the clear dentine tubules in the resorption lacuna, the shallow, unclear resorption lacuna with deposition of the hard tissue and the various steps between them were observed.
  • (7) Localised tumour forms present either in the form of large polycyclic lacunae, sometimes invaginated or as vast ulcerations with irregular nodular margin, or as due to parietal infiltration and exoluminal development of the tumour mass and neighbouring adenopathy.
  • (8) The resorbant organ, rich in odontoclasts, cementoblasts, fibroblasts, and macrophages, formed prominent resorption lacunae in root dentin.
  • (9) Signs of osteolysis, such as enlarged osteocyte lacunae surrounded by a metachromatic zone in toluidine blue stained sections, and confluence of osteocyte lacunae in microradiographs, were compared with the fluorochrome labelling pattern.
  • (10) These had networks which formed the floor of each stomata and the roof of each lacunae.
  • (11) Besides greater detailization of the prevailing diameters of the pores, the method of poremetry allows the information to be obtained concerning the distribution of not only sizes of central canals of osteons but also smaller pores characterizing the system of lacunae of osteocytes and canals connecting them.
  • (12) Osteocyte viability within the femoral head was assessed by counting empty osteocyte lacunae in five random high-power fields of hematoxylin- and eosin-stained sections.
  • (13) Lipohyalinosis, initially referred to as the underlying pathologic vascular lesion specific for lacunae, is found most commonly in a subset of patients with severe hypertension associated with multilacunar dementia.
  • (14) These areas were characterized by a matrix of amorphous blue ground substance with lacunae that contained enlarged and slightly atypical cells.
  • (15) The condition was diagnosed by biopsy of a cranial bone lacuna.
  • (16) When ascorbic acid is added to the hormone-supplemented medium, differentiating chondrocytes organize their matrix leading to a cartilage-like structure with hypertrophic chondrocytes embedded in lacunae.
  • (17) The occlusion of arterioles underneath the site suggests that circulation through the lacunae at this stage is indirect.
  • (18) The second most common cause of dementia, cerebrovascular disease, produces dementia only when there is destruction of brain tissue, as in individuals who have multiple strokes or who have hypertensive vascular disease leading to multiple lacunae.
  • (19) Macrophages and giant cells did not form pits or resorption lacunae on the bone substrates as osteoclasts did.
  • (20) These MNC express an osteoclast phenotype and form resorption lacunae on calcified matrices.