What's the difference between derange and disrupt?

Derange


Definition:

  • (v. t.) To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.
  • (v. t.) To disturb in action or function, as a part or organ, or the whole of a machine or organism.
  • (v. t.) To disturb in the orderly or normal action of the intellect; to render insane.

Example Sentences:

  • (1) It is not known whether the deposits are primary or secondary events, but they may be of importance in initiating or maintaining derangement in heart function.
  • (2) All of them had fever, jaundice, abdominal pain, leucocytosis and deranged liver function while 26.6% were in shock, 13.3% in coma and 40% in azotaemia.
  • (3) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
  • (4) The high ratio observed in BALF from patients with sarcoidosis and a chronic derangement of alveolar structure suggests either an increased C2 production or an alternative complement pathway (C2-independent) activation within their lungs.
  • (5) Progress is our understanding of the roles of vasogenic and cytotoxic brain edema in secondary brain damage can be expected from studies of the ability of biochemical factors to open the blood-brain barrier, derange the microcirculation, and cause cell swelling and necrosis.
  • (6) We assert that OCD and AVN are relatively common, clinically significant lesions of the mandibular condyle often associated with preexisting internal derangement of the temporomandibular joint.
  • (7) A hypothesis is presented as to how certain occlusal relationships and habitual patterns of jaw use may predispose an individual to TMJ internal derangements.
  • (8) These data suggest the feasibility of using calcium and EDTA infusions combined with an intact PTH assay to define the relationships between circulating levels of PTH-(1-84) and calcium in states of normal and deranged parathyroid physiology.
  • (9) Functionally, the first component reflected 55% of the reducibility property and an unimpaired oxidizability property, while the latter exhibited derangement of both aspects of cytochrome c activity.
  • (10) Laboratory investigations revealed hyperbilirubinemia, marked increase in serum transaminases, a variable alkaline phosphatase level and electrolytes derangement.
  • (11) Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization.
  • (12) A case of a patient with a malignant schwannoma, who was originally diagnosed as having internal derangement of the temporomandibular joint (TMJ), is presented.
  • (13) The consequence of these derangements is often widespread plugging of small bronchi and bronchioles.
  • (14) The deranged adenosine metabolism and raised cAMP in the platelets of this child with severe combined immunodeficiency may explain the altered response to ADP.
  • (15) Surgery has been important in the treatment of internal derangement of the TMJ.
  • (16) Biopsies of lumbar multifidus muscles were obtained at operation on seventeen patients aged from fifteen to fifty-eight with lumbar spinal derangement, and further material was taken from the cadavers of three subjects aged from nineteen to fifty-one.
  • (17) Infection, compression and metabolic derangement were implicated as the most common etiologic factors.
  • (18) The rate of decline of creatinine clearance, the changes of the urinary protein loss, of total serum protein, of the daily insulin requirement, of the nutritional status and of some hormonal derangements were examined.
  • (19) Respiratory and circulatory derangements and brain damage ensue if the problem is not promptly recognized and corrected.
  • (20) It has been suggested that the occurrence of an intracellular Ca2+ overload may result in the development of diabetic cardiomyopathy, which is associated with depletion of high-energy phosphate stores and a derangement of ultrastructure and cardiac dysfunction.

Disrupt


Definition:

  • (a.) Rent off; torn asunder; severed; disrupted.
  • (v. t.) To break asunder; to rend.

Example Sentences:

  • (1) 62.1% were from disrupted families (39.5% divorced, 12.9% remarried, and 9.7% widowed).
  • (2) Immunocytochemistry was used to visualize cytoskeletal structures and to assay selective disruption of neurofilaments by acrylamide.
  • (3) Sepsis resulted from intravenous absorption through inflamed or disrupted urothelium.
  • (4) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
  • (5) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
  • (6) This would disrupt and prevent Isis from maintaining stable and reliable sources of income.
  • (7) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
  • (8) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
  • (9) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
  • (10) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
  • (11) Displacement of the surface of the cornea of bovine eyes after disruption of intact structures was investigated by means of holographic interferometry.
  • (12) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
  • (13) The samples are first disrupted by sonication and the insoluble proteins concentrated by high-speed centrifugation.
  • (14) Electron microscopic observations of the masseter nerve in the aged cats revealed a disruption of the myelin sheaths and a pronounced increase in collagen fibers in the endoneurium and perineurium.
  • (15) Light microscopy of both apneics and snorers revealed mucous gland hypertrophy with ductal dilation and focal squamous metaplasia, disruption of muscle bundles by infiltrating mucous glands, focal atrophy of muscle fibers, and extensive edema of the lamina propria with vascular dilation.
  • (16) We propose that, for a GC base pair in B conformation, there are two amino proton exchangeable states--a cytosine amino proton exchangeable state and a guanine amino proton exchangeable state; both require the disruption of only the corresponding interbase H bond.
  • (17) No signs of the blood-brain barrier disruption were observed.
  • (18) Pupils who disrupt the learning of their classmates are dealt with firmly and, in many cases, a short suspension is an effective way of nipping bad behaviour in the bud."
  • (19) On histopathologic examination there were microabscesses in the inner choroid and subretinal space, disrupting the outer retina but sparing the inner retina.
  • (20) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.

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