(a.) Obtained by derivation; derived; not radical, original, or fundamental; originating, deduced, or formed from something else; secondary; as, a derivative conveyance; a derivative word.
(n.) That which is derived; anything obtained or deduced from another.
(n.) A word formed from another word, by a prefix or suffix, an internal modification, or some other change; a word which takes its origin from a root.
(n.) A chord, not fundamental, but obtained from another by inversion; or, vice versa, a ground tone or root implied in its harmonics in an actual chord.
(n.) An agent which is adapted to produce a derivation (in the medical sense).
(n.) A derived function; a function obtained from a given function by a certain algebraic process.
(n.) A substance so related to another substance by modification or partial substitution as to be regarded as derived from it; thus, the amido compounds are derivatives of ammonia, and the hydrocarbons are derivatives of methane, benzene, etc.
Example Sentences:
(1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(2) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(3) Leumorphin is a 29-amino-acid peptide derived from preproenkephalin B. Intracerebroventricular (i.c.v.)
(4) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
(5) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
(6) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(7) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(10) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(11) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
(12) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(13) Bipolar derivations with the maximum PSE always included the locations with the maximum PSE obtained from a linked ears reference.
(14) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(15) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
(16) The mortality data were derived from the reports by Miyagi Prefectural Government.
(17) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(18) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
(19) This doxorubicin derivative did not bind to Sepharose which was conjugated with cardiac actin.
(20) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
Polygenic
Definition:
(a.) Of or relating to polygeny; polygenetic.
Example Sentences:
(1) When power-transformed scores are used to eliminate skewness, there is evidence for one distribution and it is not possible to distinguish single gene from multifactorial (polygenic or cultural) inheritance.
(2) The polygenic control of diabetogenesis in NOD mice, in which a recessive gene linked to the major histocompatibility complex is but one of several controlling loci, suggests that similar polygenic interactions underlie this type of diabetes in humans.
(3) Inheritance of insulin-dependent diabetes mellitus (IDDM) is polygenic, and at least one of the genes conferring susceptibility to diabetes is tightly linked to the MHC.
(4) The M16 line of mice, selected for rapid postweaning gain, exhibits polygenically controlled obesity and hyperphagia.
(5) The maximum lifespan potential is a constitutional feature of speciation and must be subject to polygenic controls acting both in the domain of development and in the domain of the maintenance of macromolecular integrity.
(6) The pattern of familial clusters and the recurrence risk related to the number of affected relatives and to the severity of the disorder in the index patients support the theory of polygenic inheritance, a multifactorial-threshold aetiological model.
(7) The results showed that the low rate of bacterial clearance was recessive, that the rate of clearance was under polygenic control, and that an H-2-linked gene(s) plays a major role.
(8) The results are discussed in terms of 3 models: Lerner's concept of genetical homeostasis, additive and overdominance polygenic models.
(9) The writers agree with Mr Jiang sanduo's opinion that schizophrenic is a polygenic disease with a major dominant gene.
(10) Conditions such as these may be exclusively monogenic, polygenic or environmental, but in most cases both genetic and environmental factors are involved.
(11) The cultural model, the polygenic model, and the pseudopolygenic model share the common feature that all factors which are transmitted from parent to offspring may be represented by one parameter without any loss of information.
(12) The breeding genetic distance measure of a single locus (Carlson & Welch, 1977) is extended to polygenic traits.
(13) Polygenic variation can be maintained by a balance between mutation and stabilizing selection.
(14) Subsequent variance components analysis suggested that unmeasured polygenic loci and unmeasured shared environmental factors together account for at least an additional 36.7% of the variability in normalized fasting plasma glucose, with genes alone accounting for at least 27.3%.
(15) The posited codominant alleles represent the first single-locus component in the polygenic complexes creating susceptibility to seizures and epitomizes the small additive effects classically attributed to such genes.
(16) A new test of goodness of fit for the polygenic threshold model is proposed.
(17) Some of the abnormalities are due to detectable chromosome anomalies, while the majority of fetal abnormalities arise as a result of the interaction of polygenes and environmental factors.
(18) A general linear model of combined polygenic-cultural inheritance is described.
(19) At present, the strongest evidence is for a polygenic effect, not the effect of a single gene or gene locus.
(20) With non significant changes in triglycerides and HDL-C. We conclude that PP can be used as a complement of diet in the management of polygenic hypercholesterolemia.