(n.) The deep sensitive layer of the skin beneath the scarfskin or epidermis; -- called also true skin, derm, derma, corium, cutis, and enderon. See Skin, and Illust. in Appendix.
Example Sentences:
(1) As with alloplastic orbital implant extrusions in enucleated sockets, autogeneous dermis fat grafts can be useful in managing extrusions in previously eviscerated sockets.
(2) It increased linearly in both the epidermis and dermis, reaching nearly 100% 24 hr following its injection on Day 8.
(3) Thinning of the dermis and the arrangement of collagen in parallel bundles appear to be constant findings.
(4) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(5) The dermis from the more severely injured skin of both groups showed a homogeneous appearance ("necrosis").
(6) Applied atelocollagen was histopathologically compared with applied lyophilized porcine dermis (LPD) and controls in rats, with regard to the time course of healing.
(7) First, vasculitis extending deep into the reticular dermis or subcutaneous tissue seemed to be associated more often with systemic disease such as malignancy or connective tissue disease.
(8) Histologic examination of biopsy specimens from the involved area of skin revealed the presence of inflammatory cell infiltrates and various degrees of collagen accumulation in the dermis, subcutis, fascia, and underlying muscle.
(9) The biopsy findings consisted of eosinophilic individual necrosis of epidermal cells, satellite cell necrosis, basal liquefaction degeneration, and scanty cell infiltration into the dermis.
(10) Ten tissue sections from 10 examples of Bowen's disease were excised from paraffin blocks, rehydrated, and incubated in 90% formic acid at 45 degrees C for 18 h. The epidermis was gently removed with the aid of a dissecting microscope, and the remaining dermis with attached basal lamina was processed for scanning electron microscopy.
(11) Monoclonal antibody studies performed on biopsy specimens from both patients revealed 70% to 100% cells staining with CD5, 80% to 90% staining with CD4, 30% to 50% staining with CD8, and an increase in CD1-staining cells in the papillary dermis, indicating a predominantly helper T-cell infiltrate.
(12) The pathologic findings were dominated by lymphocytic inflammation around centrally placed follicles evolving to follicular necrosis that extended to the perifollicular epidermis and dermis.
(13) Similar vacuoles were also observed in the epidermal intercellular spaces and within the dermis.
(14) Acitretin flux through tape-stripped monkey skin and dermis was only slightly higher than through intact skin.
(15) Two had multiple nodules and the third had a single, recurrent lesion in the dermis or subcutis of the distal extremities.
(16) The increase of PGD synthetase activity in 3-week-old rats was mainly due to the increase of specific activity of PGD synthetase in the epidermis, which was separated from the dermis by heat treatment (55 degrees C, 30 s).
(17) This collagen appeared present throughout the whole dermis with slight variations at 4 months, where there was less extracellular collagen near the hair bulbs.
(18) The key assumptions are (1) that the target site is in the lower epidermis (basal layer) or in the dermis, and (2) that it is the thermodynamic activity (i.e., the free drug concentration, C*, of the active drug species) at the target site that is the true correlate of drug effectiveness.
(19) In initial lesions, CD1a+ cells represent up to 50-60% of the infiltrating cells of the dermal compartment, in several cases being preferentially localized in the upper part of the papillar dermis close up to the epidermal CD1a+ cells in basal position, whereas in chronic psoriasis they represent less than 10%.
(20) An antiserum raised in Rabbits against brain glycoprotein precipitated an identical antigen in faetal dermis and intestine extracts, and also in non nervous tumors (breast adenocarcinomas and adenofibromas, ovarian cystadenoma, gastric and colonic adenocarcinomas, hepatomas, malignant melanomas, rhabdomvosarcoma, fibrosarcomas).
Epidermis
Definition:
(v. t.) The outer, nonsensitive layer of the skin; cuticle; scarfskin. See Dermis.
(v. t.) The outermost layer of the cells, which covers both surfaces of leaves, and also the surface of stems, when they are first formed. As stems grow old this layer is lost, and never replaced.
Example Sentences:
(1) The observed staining indicated that the epithelium of the external auditory meatus has a pattern of keratin expression typical of epidermis in general and the epithelium of the middle ear resembles simple columnar epithelia.
(2) A comparison between TPA and cytokeratins was also made by immunoblotting which revealed immunoreactivity of antibodies to TPA with cytokeratin polypeptides of different species (man, mouse) and organs (epidermis, liver), particularly with the cytokeratin component 8 of human liver and the related component A of mouse liver.
(3) The enzyme profile of the epidermis was investigated in relation to depth.
(4) It increased linearly in both the epidermis and dermis, reaching nearly 100% 24 hr following its injection on Day 8.
(5) UVB irradiation augmented the beta-adrenergic adenylate cyclase response of pig skin epidermis in vitro.
(6) The kinetics of both the solube and particulate enzymes from epidermis of some elderly patients with either diabetes or ischaemia showed some differences from the kinetics of enzymes from healthy epidermis from younger individuals.
(7) These results indicate that uninvolved psoriatic epidermis has an increased capacity to metabolize free AA into 12-lipoxygenase products.
(8) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(9) At an ultrastructural level, 15-1 immunogold-labeling in the epidermis was confined to the surface of cells exhibiting Birbeck granules.
(10) The synthesis of uPA as a precursor with reduced enzymatic activity as well as decreased affinity for inhibitors is likely to be a mechanism by which normal epidermis regulates plasminogen activation in vivo.
(11) The bone marrow derivation of dThy-1+EC is now well established: dThy-1+EC carry Ly-5 determinants whose expression is restricted to cells of the hemopoietic differentiation pathway, and studies using Thy-1-disparate radiation bone marrow chimeras have revealed the presence of donor-type Thy-1+ cells within the epidermis; by immunoelectron microscopy, these cells represent dThy-1+EC.
(12) Exposure of neutrophils to AS resulted in deactivation to AS but not to Escherichial coli or Staphylococcus epidermis culture filtrate.
(13) The delta-PKC-like kinase of mouse epidermis (p82-kinase) was down-regulated after topical application of 12-O-tetradecanoylphorbol-13-acetate (TPA) to mouse skin.
(14) The purpose of this report is to present the kinetics of reduction of epidermal mass following the production of the epidermal hyperplasia as the epidermis returns to its normal thickness during the period of regression.
(15) Immunoreactivity was restricted to the periderm and intermediate layers of fetal epidermis at 55 d of gestation, when the first wave of wool follicles are initiated.
(16) In hatched larvae around developmental stage 46, strong expression of 2NI-36 was observed in several tissues including the vascular endothelium, the pigmented epithelium and the inner layer of skin epidermis.
(17) Our results show that two major types of terminally differentiating keratinocytes can be distinguished in human epidermis, i.e.
(18) This results suggest the presence of structural abnormalities in epidermis of EB simplex.
(19) By contrast, epidermal Langerhans cell (LC) HLA-DR and T6 expressions in normal epidermis were greatly reduced by an identical dose of UVB.
(20) This calcium-binding protein was not in skin epidermis, but was confined to the dermal layer.