(n.) The deep sensitive layer of the skin beneath the scarfskin or epidermis; -- called also true skin, derm, derma, corium, cutis, and enderon. See Skin, and Illust. in Appendix.
Example Sentences:
(1) As with alloplastic orbital implant extrusions in enucleated sockets, autogeneous dermis fat grafts can be useful in managing extrusions in previously eviscerated sockets.
(2) It increased linearly in both the epidermis and dermis, reaching nearly 100% 24 hr following its injection on Day 8.
(3) Thinning of the dermis and the arrangement of collagen in parallel bundles appear to be constant findings.
(4) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(5) The dermis from the more severely injured skin of both groups showed a homogeneous appearance ("necrosis").
(6) Applied atelocollagen was histopathologically compared with applied lyophilized porcine dermis (LPD) and controls in rats, with regard to the time course of healing.
(7) First, vasculitis extending deep into the reticular dermis or subcutaneous tissue seemed to be associated more often with systemic disease such as malignancy or connective tissue disease.
(8) Histologic examination of biopsy specimens from the involved area of skin revealed the presence of inflammatory cell infiltrates and various degrees of collagen accumulation in the dermis, subcutis, fascia, and underlying muscle.
(9) The biopsy findings consisted of eosinophilic individual necrosis of epidermal cells, satellite cell necrosis, basal liquefaction degeneration, and scanty cell infiltration into the dermis.
(10) Ten tissue sections from 10 examples of Bowen's disease were excised from paraffin blocks, rehydrated, and incubated in 90% formic acid at 45 degrees C for 18 h. The epidermis was gently removed with the aid of a dissecting microscope, and the remaining dermis with attached basal lamina was processed for scanning electron microscopy.
(11) Monoclonal antibody studies performed on biopsy specimens from both patients revealed 70% to 100% cells staining with CD5, 80% to 90% staining with CD4, 30% to 50% staining with CD8, and an increase in CD1-staining cells in the papillary dermis, indicating a predominantly helper T-cell infiltrate.
(12) The pathologic findings were dominated by lymphocytic inflammation around centrally placed follicles evolving to follicular necrosis that extended to the perifollicular epidermis and dermis.
(13) Similar vacuoles were also observed in the epidermal intercellular spaces and within the dermis.
(14) Acitretin flux through tape-stripped monkey skin and dermis was only slightly higher than through intact skin.
(15) Two had multiple nodules and the third had a single, recurrent lesion in the dermis or subcutis of the distal extremities.
(16) The increase of PGD synthetase activity in 3-week-old rats was mainly due to the increase of specific activity of PGD synthetase in the epidermis, which was separated from the dermis by heat treatment (55 degrees C, 30 s).
(17) This collagen appeared present throughout the whole dermis with slight variations at 4 months, where there was less extracellular collagen near the hair bulbs.
(18) The key assumptions are (1) that the target site is in the lower epidermis (basal layer) or in the dermis, and (2) that it is the thermodynamic activity (i.e., the free drug concentration, C*, of the active drug species) at the target site that is the true correlate of drug effectiveness.
(19) In initial lesions, CD1a+ cells represent up to 50-60% of the infiltrating cells of the dermal compartment, in several cases being preferentially localized in the upper part of the papillar dermis close up to the epidermal CD1a+ cells in basal position, whereas in chronic psoriasis they represent less than 10%.
(20) An antiserum raised in Rabbits against brain glycoprotein precipitated an identical antigen in faetal dermis and intestine extracts, and also in non nervous tumors (breast adenocarcinomas and adenofibromas, ovarian cystadenoma, gastric and colonic adenocarcinomas, hepatomas, malignant melanomas, rhabdomvosarcoma, fibrosarcomas).
Mesoderm
Definition:
(n.) The layer of the blastoderm, between the ectoderm and endoderm; mesoblast. See Illust. of Blastoderm and Ectoderm.
(n.) The middle body layer in some invertebrates.
(n.) The middle layer of tissue in some vegetable structures.
Example Sentences:
(1) Small pieces of anterior and posterior quail wing-bud mesoderm (HH stages 21-23) were placed in in vitro culture for up to 3 days.
(2) Here we report direct measurements of protein kinase C (PKC) activity in uninduced ectoderm, and in neuroectoderm shortly after induction by the involuting mesoderm, in Xenopus laevis embryos.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) However, the pattern in the central nervous system (CNS) and mesoderm is further restricted; the major expression located in the labial neuromere of the CNS and the mesoderm of the first thoracic segment.
(5) The positive reaction for keratin and vimentin confirmed the presence of ectodermal and mesodermal elements respectively in the tumor.
(6) Little deficit in total mesodermal cell number was found, though the entire mesoderm adopted the histological character proper to only some 40% of that in the normal pattern i.e.
(7) LIF inhibits differentiation under several conditions which lead to endodermal and mesodermal cell lineages including skeletal and cardiac muscle.
(8) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
(9) This suggests that a factor in the lateral plate mesoderm in addition to the pronephric duct is inhibiting further ventral migration.
(10) While such speculation on how these spatially separated anomalies develop is probably simplistic, the concept of a mesodermal "malformation" spectrum is helpful in reminding the clinician to look for other mesodermal defects when one mesodermally derived defect or sequence is detected.
(11) Cell biological evidence suggests that mesoderm formation and specification of axial positions occur simultaneously.
(12) The tissues of the endodermal and mesodermal origin were also present in small quantities.
(13) There mesodermal expansion proximal to an arrested edge could be compared with that proximal to a moving edge by measuring the amount of vascular elongation occurring in each.
(14) We also assessed the ability of ta2 limb bud mesoderm to respond to a polarizing signal.
(15) Invaginating mesodermal cells of the lateral and ventral parts also form pseudopodia, and are in contact with the blastocoelic wall.
(16) The aim of this study is to test the ability of the intrinsic wing musculature to develop in the absence of somitic mesoderm.
(17) Maintenance of GHox-8 expression by the anterior mesoderm appears to be independent of the presence of the apical ridge.
(18) Multiple hamartoma syndrome, also known as Cowden's disease, is a rare genodermatosis with multiple organ system involvement affecting tissues derived from ectodermal, endodermal, and mesodermal tissue layers.
(19) A unique pattern for a carbohydrate antigen is displayed by cells of the primitive streak; antigenicity is lost with de-epithelialisation and ingression, but is regained in a pericellular distribution on the mesoderm cells that emerge from the primitive streak.
(20) In the mutants twist and snail, which fail to differentiate the ventrally derived mesoderm, mitoses specific to the mesoderm are absent.