(n.) The act of despairing or becoming desperate; a giving up of hope.
(n.) A state of despair, or utter hopeless; abandonment of hope; extreme recklessness; reckless fury.
Example Sentences:
(1) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(2) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(3) While they may always be encumbered by censorship in a way that HBO is not, the success of darker storylines, antiheroes and the occasional snow zombie will not be lost in an entertainment industry desperate to maintain its share of the audience.
(4) Many hope this week's photocalls with the two men will be a recruiting aid and provide a desperately needed bounce in the polls.
(5) Hamilton said it was uncanny to find themselves in another desperate emergency situation almost exactly one year on.
(6) There are numerous other male protagonists out there in desperate need of a sex change.
(7) Frederick Juuko, a Ugandan law professor and critic of foreign influence in Ugandan politics, agrees that homosexuality is a pawn for many in times of desperation, including government.
(8) 9.23pm GMT Expect the reporters to get even more speculative and desperate from hereon in.
(9) He said: “Almost daily we hear from parents desperate to escape the single cramped room of a B&B or hostel that they find themselves struggling to raise their children in.
(10) The report's authors warns that to limit their spending councils will have "an incentive to discourage low-income families from living in the area" and that raises the possibility that councils will – like the ill-fated poll tax of the early 1990s – be left to chase desperately poor people through the courts for small amounts of unpaid tax.
(11) The local MP, Rory Stewart, a mover and shaker on the broadband project, told me that he was desperate to get telehealth into Cumbria, but regretfully felt that it was not immediately doable, because the local council and healthcare community did not yet have the necessary expertise.
(12) In desperation, I cancelled my contract with Sky and placed a new order with BT in February.
(13) When I heard it, I thought of Sherpa as a first name, like the Edmund in Edmund Hillary, rather than as a description, like the Desperate in Desperate Dan.
(14) Clark said he first met Brown in November 2004, just a few months before the general election when the party was in desperate need of funds.
(15) I tried desperately hard not to influence her, but I did steer her away from a baby that I've already bought her for her Christmas present.
(16) Patel once wrote: “At one end of this world, there is one woman who desperately needs a baby and cannot have her own child.
(17) Families like these are being abandoned to their fate and, as Steve Hynes of the Legal Action Group says: "These are often truly desperate people."
(18) Michael Holroyd, in his biography of George Bernard Shaw , gives an illuminating example of myopic hostility to Russia by the right even when we desperately needed allies.
(19) Police reinforcements are being sent to the embattled port of Calais in an attempt to prevent increasingly desperate attempts by migrants to gain access to the UK.
(20) "I desperately don't want this to suppress people's choice and freedom," says Stansfield.
Determination
Definition:
(n.) The act of determining, or the state of being determined.
(n.) Bringing to an end; termination; limit.
(n.) Direction or tendency to a certain end; impulsion.
(n.) The quality of mind which reaches definite conclusions; decision of character; resoluteness.
(n.) The state of decision; a judicial decision, or ending of controversy.
(n.) That which is determined upon; result of deliberation; purpose; conclusion formed; fixed resolution.
(n.) A flow, rush, or tendency to a particular part; as, a determination of blood to the head.
(n.) The act, process, or result of any accurate measurement, as of length, volume, weight, intensity, etc.; as, the determination of the ohm or of the wave length of light; the determination of the salt in sea water, or the oxygen in the air.
(n.) The act of defining a concept or notion by giving its essential constituents.
(n.) The addition of a differentia to a concept or notion, thus limiting its extent; -- the opposite of generalization.
(n.) The act of determining the relations of an object, as regards genus and species; the referring of minerals, plants, or animals, to the species to which they belong; classification; as, I am indebted to a friend for the determination of most of these shells.
Example Sentences:
(1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
(5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
(6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
(10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
(11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
(17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.