(n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
(n.) To vex; to annoy; to offend contemptuously.
(prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
(7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
(8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
(10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
(12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
(13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
(14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
(18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
(19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
(20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.
Disdain
Definition:
(v. t.) A feeling of contempt and aversion; the regarding anything as unworthy of or beneath one; scorn.
(v. t.) That which is worthy to be disdained or regarded with contempt and aversion.
(v. t.) The state of being despised; shame.
(v. t.) To think unworthy; to deem unsuitable or unbecoming; as, to disdain to do a mean act.
(v. t.) To reject as unworthy of one's self, or as not deserving one's notice; to look with scorn upon; to scorn, as base acts, character, etc.
(v. i.) To be filled with scorn; to feel contemptuous anger; to be haughty.
Example Sentences:
(1) People praying, voicing their views and heart, were met with disdain and a level of force exceeding what was needed.
(2) Fred had to be substituted to shield him from the crowd’s disdain.
(3) It may have been like punk never ‘appened, but you caught a whiff of the movement’s scorched earth puritanism in the mocking disdain with which Smash Hits addressed rock-star hedonism.
(4) TV's Jeremy Paxman didn't even bother hiding his disdain for the introduction of weather reports to Newsnight – "It's April.
(5) It shows that we still have some way to go to end bigoted banter.” The exchange was also met with disdain on Twitter.
(6) He has frequently tested the patience of Japan's conservative sumo authorities with his disdain for the rules of engagement in the ring and his bad behaviour off it.
(7) His comic adventures are too many to relate, but it may be said that they culminate in a café of 'singing waiters' where, after a wealth of comic 'business' with the tray, he shows his disdain for articulate speech by singing a vividly explicit song in gibberish.
(8) Immigration has been used as a 21st-century incomes policy, mixing a liberal sense of free for all with a free-market disdain for clear and effective rules.
(9) Riva, the oldest nominee ever for best actress category, has a very Gallic disdain for such public adulation.
(10) "Historians will pore over his many speeches to black audiences," wrote Ta-Nahisi Coates at The Atlantic, and "they will see a president who sought to hold black people accountable for their communities, but was disdainful of those who looked at him and sought the same".
(11) Born in July 1954, Christopher Murray Paul-Huhne (his surname until he went to Oxford) has always been something of a Marmite politician, attracting both loyalty and affection, as well as brickbats and disdain.
(12) Gil Eliyahu, who stopped working for Binyamin and Sara Netanyahu two and a half years ago, is threatening to sue the couple, claiming he was treated with "humiliating" disdain.
(13) It was one of at least half a dozen such unionist experiments, with a variety of partners, which foundered on the rocks of the would-be partners' infirmity of purpose, fear, suspicion and disdain of this bizarre, arrogant, impetuous upstart.
(14) Safronkov reserved his fiercest disdain for the UK envoy, Matthew Rycroft, who had said that UK scientists had determined that sarin had been used in the Khan Sheikhun attack and called on Russia to cut ties with Assad, who Rycroft said was bringing Moscow only “shame and humiliation”.
(15) The rules extended from healthcare to the environment to workplace safety, but all were grounded in Bush's disdain for the government's role as a regulatory authority.
(16) Stevenson did not disdain the genre in which he was operating.
(17) Issues Sir Ken, on the other hand, is a professional Yorkshireman and farmer - the sort of chap who prefers to call a retail outlet a shop and treated press and City with equal disdain.
(18) The pent-up fury of the parents reflected the intensity of the violent protests that marked a dramatic week in Mexico, which has deepened the political crisis facing President Enrique Peña Nieto as he returns from a week-long trip to China and Australia, seen by many as a sign of disdain for the suffering and anger at home.
(19) What is clear now, for those for whom it was ever in doubt, is the reality of Tory values: the disdain with which they view the less fortunate and the reason why the annual cull of the impoverished through malnutrition and hypothermia is not a problem to them.
(20) Instead – spoiler alert – to the disdain of many, it opted for a more satisfying, upbeat conclusion.