What's the difference between despite and however?

Despite


Definition:

  • (n.) Malice; malignity; spite; malicious anger; contemptuous hate.
  • (n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
  • (n.) To vex; to annoy; to offend contemptuously.
  • (prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.

Example Sentences:

  • (1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
  • (2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
  • (3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
  • (4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
  • (5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
  • (7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
  • (8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
  • (9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
  • (10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
  • (11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
  • (12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
  • (13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
  • (14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
  • (15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
  • (16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
  • (17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
  • (18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
  • (19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
  • (20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.

However


Definition:

  • (adv.) In whetever manner, way, or degree.
  • (adv.) At all events; at least; in any case.
  • (conj.) Nevertheless; notwithstanding; yet; still; though; as, I shall not oppose your design; I can not, however, approve of it.

Example Sentences:

  • (1) However, patients with GGBHS were significantly older (P less than .05).
  • (2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
  • (3) This may have significant consequences for people’s health.” However, Prof Peter Weissberg, medical director of the British Heart Foundation, which funded the work, said medical journals could no longer be relied on to be unbiased.
  • (4) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
  • (5) Unfortunately, due to confidentiality clauses that have been imposed on us by the Department of Immigration and Border Protection, we are unable to provide our full names and … titles … However, we believe the evidence that will be submitted will validate the statements that we are making in this submission.” The submission detailed specific allegations – including names and dates – of sexual abuse of child detainees, violence and bullying of children, suicide attempts by children and medical neglect.
  • (6) However, this deficit was observed only when the sample-place preceded but not when it followed the interpolated visits (second experiment).
  • (7) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
  • (8) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
  • (9) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
  • (10) However, dexamethasone was more effective than either prednisone or cortisol (P less than 0.001).
  • (11) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
  • (12) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
  • (13) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).
  • (14) However, some contactless transactions are processed offline so may not appear on a customer’s account until after the block has been applied.” It says payments that had been made offline on the day of cancellation may be applied to accounts and would be refunded when the customer identified them; payments made on days after the cancellation will not be taken from an account.
  • (15) However, the groups often paused less and responded faster than individual rats working under identical conditions.
  • (16) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
  • (17) However it is important to recognize these cysts so that correct surgical management is offered to the patient.
  • (18) Surgical repair of the rheumatologic should however, is performed rarely, and should be reserved for the infrequent cases that do not respond to medical therapy.
  • (19) However, there was no correlation between the length of time PN was administered to onset of cholestasis and the gestational age or birth weight of the infants.
  • (20) In practice, however, the necessary dosage is difficult to predict.