(n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
(n.) To vex; to annoy; to offend contemptuously.
(prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
(7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
(8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
(10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
(12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
(13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
(14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
(18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
(19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
(20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.
In
Definition:
(prep.) The specific signification of in is situation or place with respect to surrounding, environment, encompassment, etc. It is used with verbs signifying being, resting, or moving within limits, or within circumstances or conditions of any kind conceived of as limiting, confining, or investing, either wholly or in part. In its different applications, it approaches some of the meanings of, and sometimes is interchangeable with, within, into, on, at, of, and among.
(prep.) With reference to space or place; as, he lives in Boston; he traveled in Italy; castles in the air.
(prep.) With reference to circumstances or conditions; as, he is in difficulties; she stood in a blaze of light.
(prep.) With reference to a whole which includes or comprises the part spoken of; as, the first in his family; the first regiment in the army.
(prep.) With reference to physical surrounding, personal states, etc., abstractly denoted; as, I am in doubt; the room is in darkness; to live in fear.
(prep.) With reference to character, reach, scope, or influence considered as establishing a limitation; as, to be in one's favor.
(prep.) With reference to movement or tendency toward a certain limit or environment; -- sometimes equivalent to into; as, to put seed in the ground; to fall in love; to end in death; to put our trust in God.
(prep.) With reference to a limit of time; as, in an hour; it happened in the last century; in all my life.
(adv.) Not out; within; inside. In, the preposition, becomes an adverb by omission of its object, leaving it as the representative of an adverbial phrase, the context indicating what the omitted object is; as, he takes in the situation (i. e., he comprehends it in his mind); the Republicans were in (i. e., in office); in at one ear and out at the other (i. e., in or into the head); his side was in (i. e., in the turn at the bat); he came in (i. e., into the house).
(adv.) With privilege or possession; -- used to denote a holding, possession, or seisin; as, in by descent; in by purchase; in of the seisin of her husband.
(n.) One who is in office; -- the opposite of out.