What's the difference between despite and instead?

Despite


Definition:

  • (n.) Malice; malignity; spite; malicious anger; contemptuous hate.
  • (n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
  • (n.) To vex; to annoy; to offend contemptuously.
  • (prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.

Example Sentences:

  • (1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
  • (2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
  • (3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
  • (4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
  • (5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
  • (7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
  • (8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
  • (9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
  • (10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
  • (11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
  • (12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
  • (13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
  • (14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
  • (15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
  • (16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
  • (17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
  • (18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
  • (19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
  • (20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.

Instead


Definition:

  • (adv.) In the place or room; -- usually followed by of.
  • (adv.) Equivalent; equal to; -- usually with of.

Example Sentences:

  • (1) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
  • (2) Maybe the world economy goes tits up again, only this time we punish the rich instead of the poor.
  • (3) Instead, the White House opted for a low-key approach, publishing a blogpost profiling Trinace Edwards, a brain-tumour victim who recently discovered she was eligible for Medicaid coverage.
  • (4) Keep it in the ground campaign Though they draw on completely different archives, leaked documents, and interviews with ex-employees, they reach the same damning conclusion: Exxon knew all that there was to know about climate change decades ago, and instead of alerting the rest of us denied the science and obstructed the politics of global warming.
  • (5) Instead of later renal failure and, of course, mental retardation, it was the histological features of the fetus eyes which permit to diagnose and exhibit both congenital cataract and irido-corneal angle dysgenesis.
  • (6) It was recently demonstrated that MRL-lpr lymphoid cells transferred into lethally irradiated MRL- +mice unexpectedly failed to induce the early onset of lupus syndrome and massive lymphadenopathy of the donor, instead they caused a severe wasting syndrome resembling graft-vs-host (GvH) disease.
  • (7) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
  • (8) Instead, he handed over the opening to reporter Molly Line, who said, “Racial profiling is in the eye of the beholder,” before citing differing perceptions of the phenomenon between white and black people, which is like reading the headline “Rapist, Victim Differ on Consent”.
  • (9) It is intended to aid in finding the appropriate PI (proportional-integral) controller settings by means of computer simulation instead of real experiments with the system.
  • (10) Urban hives boom could be 'bad for bees' What happened: Two professors from a University of Sussex laboratory are urging wannabe-urban beekeepers to consider planting more flowers instead of taking up the increasingly popular hobby.
  • (11) Furthermore, even the action of Lys-5 on the Pseudomonas OM was abolished when the assays were performed in the presence of 150 mM NaCl instead of the low-ionic strength buffer earlier used by investigators studying the effect of polycations on the Pseudomonas OM.
  • (12) Instead, we suffer sporadic exhibitions, which they call consultation.
  • (13) Instead of healing the nation after a fractious referendum he inflamed the situation.
  • (14) Instead, an antiarrhythmic drug should be administered and another shock of the same intensity that defibrillated the first time should be applied.
  • (15) When rabbit and horse sera were used instead of human serum for cultivation, in both groups the share of positive cultures increased and more large forms of B. hominis cells were observed.
  • (16) Instead, they say, we should only eat plenty of lean meat and fish, with fruit and raw vegetables on the side.
  • (17) Orbital hypertelorism, strictly defined as an increase in bony interorbital distance, is not itself an isolated syndrome, but is instead an anomaly that may occur as either part of a syndrome or malformation sequence.
  • (18) She said the rise in fees was not part of the effort to tackle the deficit, but was instead about Clegg "going along with Tory plans to shove the cost of higher education on to students and their families".
  • (19) When my form teacher said I’d worked well in every subject except geography, I made her change the bit that said I’d not tried to say, instead, that I was rubbish at it.
  • (20) Instead, a repetitive, stepwise dissolution pattern was observed.