(n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
(n.) To vex; to annoy; to offend contemptuously.
(prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
(7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
(8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
(10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
(12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
(13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
(14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
(18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
(19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
(20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.
Notwithstanding
Definition:
(prep.) Without prevention, or obstruction from or by; in spite of.
(adv. / conj.) Nevertheless; however; although; as, I shall go, notwithstanding it rains.
Example Sentences:
(1) These data notwithstanding, the role of SIV genetic variation in the pathogenesis of AIDS in monkeys remains unclear.
(2) Notwithstanding the fact that rubella vaccination has been recommended for all school-girls since 1973, no significant difference was noticed between the seropositivity rates of healthy females aged 18-23 observed in the period 1973-78 (i.e.
(3) Articles in the popular press notwithstanding, data from the 1984 National Long-term Care Survey indicate that a relatively small number of adult children and spouses assume the multiple responsibilities of elder care and child care or employment.
(4) Notwithstanding, the short-term prognosis for typhlitis remains poor.
(5) The advantages of having two X chromosomes are apparent, notwithstanding X-chromosome inactivation.
(6) The paper proposes that in post-behaviouristic and post-phenomenological times an integration of frames of reference, designs and methodologies ought to be attempted, notwithstanding serious dissonances, disagreements, and professions-bound interests.
(7) Notwithstanding these differences, the positions of all the vocal folds in extreme adduction or abduction were similar.
(8) This section was memorably captured by the computer and security expert Caspar Bowden , who wrote: "Interpreting that section requires the unravelling of a triple-nested inversion of meanings across six cross-referenced subsections, linked to a dozen other cross-linked definitions, which are all dependent on a highly ambiguous 'notwithstanding'."
(9) This is because determinants of flexion after TKA are multifactorial and outcome data limited, notwithstanding the similarities among modern prostheses.
(10) The success of Capote paved the way for bigger and more nuanced parts for Hoffman, his turn as the villain in Mission: Impossible III (2006) notwithstanding.
(11) Notwithstanding the complexities involved in the absorption processes, the data support the hypothesis that the absorption of organic electrolytes mainly takes place by the partitioning of the unionized species into the lipoidal membranes and then diffusion.
(12) These results, when viewed together with those reported in humans with ARDS and in dogs with ethchlorvynol-induced ALI, support the hypothesis that leukotriene detection in BALF is a feature common to ALI, etiology notwithstanding.
(13) Within selected planes, DRESS are spatially restricted by the surface coil sensitivity profiles to disk-shaped volumes whose radii increase with depth, notwithstanding variations in the NMR signal density distribution.
(14) Notwithstanding, each index can serve a useful role in quantitating method agreement in carefully considered situations.
(15) This means that notwithstanding a tight pay offer, total investment by the BBC in its people will go up.
(16) Labelled IGF-2 bound predominantly to the type 2 receptor with negligible label cross-linked to the type 1 receptor, notwithstanding the ability of IGF-2 to compete effectively for the binding of IGF-1 to the type 1 receptor.
(17) Notwithstanding important advances in the treatment of epilepsy basic knowledge about the epilepsies and about the mechanism of action of antiepileptic drugs is still fragmentary.
(18) Notwithstanding the latent benefits and cost savings that corporate management expects to gain from the investment in such programs, it is argued that workplace health promotion is not without potential misuse and that its goals and methods ought not to be above ethical scrutiny.
(19) This speech was designed to allow progressives once again to see Barack Obama as they have always wanted to see him, his policies notwithstanding: as a deeply thoughtful, moral, complex leader who is doing his level best, despite often insurmountable obstacles, to bring about all those Good Things that progressives thought they would be getting when they empowered him.
(20) In the course of an infectious episode and notwithstanding an increase in EPO dosage, 2 patients exhibited a fall in hemoglobin which rose again after successful treatment of the infection.