(n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
(n.) To vex; to annoy; to offend contemptuously.
(prep.) In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(5) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(6) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
(7) In conclusion, abdominal Marlex-mesh rectopexy can be recommended as safe and effective treatment for rectal prolapse, despite some patients developing constipation and some remaining incontinent.
(8) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(9) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
(10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(11) In addition, despite the fact that the differences constitutes an information bias, the bias occurs in the same direction and magnitude in all the various subgroups and thus is nondifferential.
(12) Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth.
(13) Despite significant differences in mean response, there was a large overlap of individual responses between diagnostic subgroups.
(14) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(15) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(16) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(17) John Lewis’s marketing, advertising and reputation are all built on their promises of good customer services, and it is a large part of what still drives people to their stores despite cheaper online outlets.
(18) Despite the nearly anaerobic state of the ascites tumor fluid in vivo, cancer cells suspended in this fluid oxidized FFA at least as fast as they do in vitro under aerobic conditions.
(19) Conservatively treated compressed fractures of the distal radius dorsal metaphysis healed despite primarily good reduction and consequent treatment with a decrease in dorsal length.
(20) The diagnosis of an arterial injury may be readily apparent, but the excellent upper-extremity collateral circulation may create palpable distal pulses despite a significant proximal arterial injury.
Vex
Definition:
(v. t.) To to/s back and forth; to agitate; to disquiet.
(v. t.) To make angry or annoyed by little provocations; to irritate; to plague; to torment; to harass; to afflict; to trouble; to tease.
(v. t.) To twist; to weave.
(v. i.) To be irritated; to fret.
Example Sentences:
(1) De Boer's successor's first tasks will be to keep the US aboard the negotiations and to clear up the vexed question of the legal status of the Copenhagen accord , the deal struck at Copenhagen by a small group but not endorsed by a majority of countries.
(2) There is also the vexed question of what should be the legal form of any Paris agreement, a subject likely to keep negotiators up late into the night at the conference, and some anxiety among the hosts over whether the text of a deal can be formulated in due time.
(3) But the bigger question, the one that has vexed historians, biographers and holocaust experts for eight decades, is why she was there.
(4) Cs (2 mM) reduced diastolic depolarization (DD) at different [Ca]O and in 10.8 mM [Ca]O revealed an oscillatory potential (VOS) and the decay of a prolonged depolarization (Vex).
(5) The past few days have been vexing ones for reporting guidelines, voluntary or legal.
(6) The present data also highlighted the vexed relationship between stress and seizure control, which needs to be further investigated.
(7) Another vexed national question in the coming months will be this one: who is the most worthy winner of BBC Sports Personality of the Year?
(8) Delivery of monoclonal antibodies to solid tumors is a vexing problem that must be solved if these antibodies are to realize their promise in therapy.
(9) Pathologists without considerable experience in the diagnosis of bone tumors find this question especially vexing.
(10) Caffeine (5 mM) abolishes Vos and Ios and increases Vex and Iex (as DOXO does), and adding DOXO slightly increased Vex and Iex.
(11) Posttraumatic joint stiffness is particularly vexing in the small joints.
(12) In this spirit, a vignette is offered from a clinical area in which questions of "health" and "illness" are particularly vexing at present.
(13) Some might argue that our eyes weren't quite on the ball back in '89: never mind the cataclysmic political upheaval in eastern Europe – the results of which still echo around the world – let's devote ourselves to a page concerned with vexed questions such as: why is water wet?
(14) The draft provides scant details on the vexed subject of accountability for emission reduction programmes.
(15) Nowhere was the commission’s balancing act more finely weighted than on the vexed question of bioenergy, which Cañete admitted was “a clear problem”.
(16) The top Chinese negotiator, Xie Zhenhua, said there was also a possibility of advances on the vexed issued of transparency – how to monitor, report and verify each nation's emissions to ensure they are honouring their pledges.
(17) But now it’s Isis who are the insurgents,” leaving the peshmerga with the vexing challenge of defending and holding territory.
(18) On the vexed issue of longer term finance, the Ethiopian prime minister Meles Zenawi presented an offer to reduce developing country demands by 75% to $100bn a year from 2020, in return for guarantees of how the money would be distributed.
(19) Discussed here are some contours of the vexing problem of adequate minority participation in the health professions and a brief discussion of some programs that appear to be working.
(20) After the creed and some Benjamin Britten, and a blessing and a long round of applause, the man charged with holding together the fractious global Anglican communion as it struggles with the vexed issues of women bishops and same-sex marriage processed out of the cathedral and into the bitterly cold spring afternoon.