(a.) Marked by despondence; given to despondence; low-spirited; as, a despondent manner; a despondent prisoner.
Example Sentences:
(1) After she hit the two-year mark, five-month mark, she’s been despondent.
(2) It was hard to reconcile Pistorius's despondent figure in black suit and tie and white shirt with the "blade runner" who thrilled stadiums around the world and became the first amputee to run in the Olympics .
(3) But actually what we felt as the days and weeks passed – me and Kelly and my father – was a sense of despondency, of being let down, of just sinking through the system.
(4) In 46%, the subject had expressed despondency over illness.
(5) There is a sense of despondency spreading in Pakistan.
(6) The value of Brazil's currency, the real, has ballooned since President Lula took power, leaving exporters despondent and leading Goldman Sachs to classify it as the most overvalued currency on earth.
(7) , became a battle manual for despondent Democrats after George W Bush’s second election victory.
(8) He told worshippers at Durham cathedral: "It is very easy to be despondent about the church.
(9) Pablo Simón, a political science professor at Madrid’s Carlos III University, argues that a fresh election and the attendant politicking could further alienate an already despondent electorate.
(10) In Spike Jonze 's Her, set in a near future LA, Phoenix is Theodore, a despondent, solitary writer whose life picks up when he falls in love with Samantha, a portable, artificially intelligent operating system who provides more than he could have hoped for.
(11) [It is] all the Ds: despair, depression, despondency.” “Chinese media are under a lot of pressure right now.
(12) Jose Mourinho: Rafa Benitez destroyed my work at Inter within six months Read more There wasn’t too much to get excited or despondent about in any of the displays in New York, Charlotte or here in Washington DC.
(13) Rob came very close to death many times, and I think part of James's despondency now comes from having saved Rob so many times, only to lose him in the end.
(14) They have been left despondent by Francis's occasional comments on the issue, in which he has generally defended the church while condemning the abuse.
(15) Despondent MPs tonight voiced fears that Britain may experience a milder version of the "clean hands" affair that brought down Italy's postwar political settlement in the 1990s.
(16) Strong was despondent over Bilibid but recovered and developed a noteworthy career in American tropical medicine.
(17) It has been demonstrated that a small proportion of women taking oral contraceptives develop a depressive syndrome characterized by despondency, tension, and changes in sex desire.
(18) A classic portrait of the grieving widower, his despondency did not surprise mental health professionals.
(19) For those who don't get the results they hoped for – and their chosen universities – the moments after the envelope are full of dread and despondency.
(20) It is easy to see why players bounce off Klopp and indeed it was tempting to wonder if Chelsea’s despondent players were casting the occasional envious glance at the German, whose energetic and engrossing touchline demeanour offered a welcome shade of light next to José Mourinho ’s dark scowl.
Low
Definition:
() strong imp. of Laugh.
(v. i.) To make the calling sound of cows and other bovine animals; to moo.
(n.) The calling sound ordinarily made by cows and other bovine animals.
(n.) A hill; a mound; a grave.
(n.) Fire; a flame; a light.
(v. i.) To burn; to blaze.
(superl.) Occupying an inferior position or place; not high or elevated; depressed in comparison with something else; as, low ground; a low flight.
(superl.) Not rising to the usual height; as, a man of low stature; a low fence.
(superl.) Near the horizon; as, the sun is low at four o'clock in winter, and six in summer.
(superl.) Sunk to the farthest ebb of the tide; as, low tide.
(superl.) Beneath the usual or remunerative rate or amount, or the ordinary value; moderate; cheap; as, the low price of corn; low wages.
(superl.) Not loud; as, a low voice; a low sound.
(superl.) Depressed in the scale of sounds; grave; as, a low pitch; a low note.
(superl.) Made, as a vowel, with a low position of part of the tongue in relation to the palate; as, / (/m), / (all). See Guide to Pronunciation, // 5, 10, 11.
(superl.) Near, or not very distant from, the equator; as, in the low northern latitudes.
(superl.) Numerically small; as, a low number.
(superl.) Wanting strength or animation; depressed; dejected; as, low spirits; low in spirits.
(superl.) Depressed in condition; humble in rank; as, men of low condition; the lower classes.
(superl.) Mean; vulgar; base; dishonorable; as, a person of low mind; a low trick or stratagem.
(superl.) Not elevated or sublime; not exalted or diction; as, a low comparison.
(superl.) Submissive; humble.
(superl.) Deficient in vital energy; feeble; weak; as, a low pulse; made low by sickness.
(superl.) Moderate; not intense; not inflammatory; as, low heat; a low temperature; a low fever.
(superl.) Smaller than is reasonable or probable; as, a low estimate.
(superl.) Not rich, high seasoned, or nourishing; plain; simple; as, a low diet.
(n.) The lowest trump, usually the deuce; the lowest trump dealt or drawn.
(adv.) In a low position or manner; not aloft; not on high; near the ground.
(adv.) Under the usual price; at a moderate price; cheaply; as, he sold his wheat low.
(adv.) In a low mean condition; humbly; meanly.
(adv.) In time approaching our own.
(adv.) With a low voice or sound; not loudly; gently; as, to speak low.
(adv.) With a low musical pitch or tone.
(adv.) In subjection, poverty, or disgrace; as, to be brought low by oppression, by want, or by vice.
(adv.) In a path near the equator, so that the declination is small, or near the horizon, so that the altitude is small; -- said of the heavenly bodies with reference to the diurnal revolution; as, the moon runs low, that is, is comparatively near the horizon when on or near the meridian.
(v. t.) To depress; to lower.
Example Sentences:
(1) The extents of phospholipid hydrolysis were relatively low in brain homogenates, synaptic plasma membranes and heart ventricular muscle.
(2) Serum levels of both dihydralazine and metabolites were very low and particularly below the detection limit.
(3) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(4) The technique is facilitated by an amazingly low tendency to bleeding.
(5) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(6) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(7) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
(8) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(9) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(10) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(11) Low birth weight, short stature, and mental retardation were common features in the four known patients with r(8).
(12) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(13) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(14) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(15) beta-Endorphin blocked the development of fighting responses when a low footshock intensity was used, but facilitated it when a high shock intensity was delivered.
(16) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
(17) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(18) This study compared the non-invasive vascular profiles, coagulation tests, and rheological profiles of 46 consecutive cases of low-tension glaucoma with 69 similarly unselected cases of high-tension glaucoma and 47 age-matched controls.
(19) A diplomatic source said the killing appeared particularly unusual because of Farooq lack of recent political activity: "He was lying low in the past two years.
(20) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.