(n.) The act of destroying; a tearing down; a bringing to naught; subversion; demolition; ruin; slaying; devastation.
(n.) The state of being destroyed, demolished, ruined, slain, or devastated.
(n.) A destroying agency; a cause of ruin or of devastation; a destroyer.
Example Sentences:
(1) But soon after aid workers departed, barrel bombs dropped by Syrian helicopters caused renewed destruction.
(2) High mortality, severe destruction of pancreatic B-cells and presence of sporadic mononuclear infiltrations in islets and around excretory ducts were observed.
(3) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(4) Since alkaline phosphatase, a glycoprotein, is not affected, the destruction is selective and presumably involves only the most exposed membrane components.
(5) Intravenous urography revealed destruction of the right kidney resembling Wilms tumor.
(6) Lawmakers across the globe are beginning to recognize the need to deter this destructive conduct.
(7) Finally, the uptake was completely abolished by prior mechanical or osmotic destruction of the intima.
(8) The weapon is 13 metres long, weighs 60 tonnes and can carry nuclear warheads with up to eight times the destructive capacity of the bombs that hit Hiroshima and Nagasaki in the second world war.
(9) While a clearcut relationship cannot be established between heavy metal music and destructive behavior, evidence shows that such music promotes and supports patterns of drug abuse, promiscuous sexual activity, and violence.
(10) Quite the contrary, in cases of higher nervous activity disturbances, destruction of the organelles and desintegration of spine apparatuses is clearly pronounced.
(11) Granule cell destruction began early, and was widespread by 2 days in vitro, when oligodendrocyte destruction also began in treated cultures.
(12) The ferrochelatase-inhibitory activity, porphyrin-inducing activity, and cytochrome P-450- and heme-destructive effects of a variety of analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) were studied in chick embryo liver cells.
(13) A simple technique that consists of curetting the subcutaneous tissue in the necrotic area of the lesion, to prevent the local destructive actions of the toxin, is described.
(14) The high proteolytic activity of BCC demonstrated in this study may be an important factor in the proliferative, invasive and destructive behaviour of this tumour.
(15) North Korea has produced tons of propaganda films that portray America’s destruction.
(16) The object of these studies was to investigate whether destruction of the renal medulla in normal rats would alter vascular capacitance.
(17) We simply do whatever nature needs and will work with anyone that wants to help wildlife.” His views might come as a surprise to some of the RSPB’s 1.1 million members, who would have been persuaded by its original pledge “to discourage the wanton destruction of birds”; they would equally have been a surprise to the RSPB’s detractors in the shooting world.
(18) The tissue destructive process is slower in older than in younger people, and the prognoses in correctly treated cases is good.
(19) Although these two destructive entities are completely different in many respects, they share a common denominator: the initial lesions are brought about by an aggregate of bacteria known as plaque.
(20) It is concluded that the massive destruction of the normal anatomy in the lateral semicircular canal may be the morphological basis of a functional endolymphatic fistula for drainage of the endolymphatic hydrops.
Killer
Definition:
(n.) One who deprives of life; one who, or that which, kills.
(n.) A voracious, toothed whale of the genus Orca, of which several species are known.
Example Sentences:
(1) To investigate the immunomodulating properties of cis-diamminedichloroplatinum (II) (CDDP), we studied the drug's effects on natural killer (NK) lymphocyte cytotoxicity.
(2) To become president of Afghanistan , Ashraf Ghani Ahmadzai changed his wardrobe and modified his name, gave up coffee, embraced a man he once denounced as a “known killer” and even toyed with anger management classes to tame a notorious temper.
(3) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
(4) Natural killer cells (CD8+CD57+) as well as activated T cells (CD3+HLA-DR+) were significantly increased in patients with sarcoidosis.
(5) In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells.
(6) The isolated LGL were highly cytotoxic against YAC-1 lymphoma cells and this cytolytic activity was blocked by treatment of the effector cells with an antibody against natural killer cells (anti-asialo GM1).
(7) Natural killer (NK) cell activity was assessed in the peripheral blood of 20 patients with growth hormone (GH) deficiency due to a hypothalamic deficit of GH-releasing hormone (GHRH).
(8) Analysis of lymphocyte subsets by flow cytometry demonstrated Leu 4, 43.6% (T cells); Leu 10, 10.5% (B cells) and Leu 7, 13.1% (natural killer (NK) cells) in TIL.
(9) Abnormal synaptonemal complexes were seen in all 19 crosses of N. crassa and N. intermedia that were examined, including matings between standard laboratory strains, inversions, Spore killers, and strains collected from nature.
(10) In experiments using double and triple chamber cultures it was demonstrated that suppressive macrophages from advanced T8-Guérin tumor (diameter 5--6.5 cm) bearing rats produced a dialysable factor which suppressed the killer activity of lymphocytes from non-advanced T8-Guérin tumor (diameter 0.5--0.7 cm) bearing rats, as well as from nonadvanced h 18R tumor bearing rats and from Ehrlich ascites bearing mice, against T8-Guérin ascitic cells and, respectively, against h 18R ascitic and Ehrlich ascitic cells.
(11) These killer cells could lyse a wide range of syngeneic and allogeneic lymphoid tumour cell lines in vitro, and it was found that cell suspensions from nude mice were always significantly more active than those from normal mice, and that the most active effector population was a polymorph-enriched peritoneal-exudate cell suspension.
(12) These findings show that humoral factors that can inhibit natural killer cell activity in vitro are present in the peripheral blood of patients who have endometriosis; moreover, they suggest that the suppressed natural killer cell activity may allow the development of endometrial cells at ectopic sites.
(13) Trophoblasts showed low susceptibility to natural killer and lymphokine-activated cells.
(14) Lymphokine-activated killer (LAK) cells are generated in vitro by the incubation of normal murine splenocytes in interleukin 2.
(15) In contrast, TCDD exposure had no significant effect on natural killer cell function, production of interferon, or various parameters of macrophage function.
(16) To help understand host-tumor relationships in adult acute lymphoblastic leukemia (ALL) and to better define potential indications for interleukin-2 (IL-2) treatment in this disease, the relationship between the susceptibility of leukemia cells of 22 patients with ALL to lysis by allogeneic lymphokine-activated killer (LAK) cells and characteristics of the leukemia was studied.
(17) The police investigating the 1991 murder of the Oxford student Rachel McLean had a strong hunch that the killer was her boyfriend, John Tanner, another student.
(18) Interferon-alpha and IL-2 could enhance NK activity and IL-2 could generate lymphokine-activated killer activity at all stages of ALL; however, the recycling defect hardly improved with these treatments.
(19) I read somewhere that one of the actresses you admire is Charlize Theron and she's another great beauty who started out modelling but whose breakthrough role came when she uglied up [to play serial killer Aileen Wuornos in Monster ].
(20) The present work investigated the association between prostaglandin E2 (PGE2) from macrophages and its inhibition of murine lymphokine-activated killer (LAK) cell generation.