(a.) Causing destruction; tending to bring about ruin, death, or devastation; ruinous; fatal; productive of serious evil; mischievous; pernicious; -- often with of or to; as, intemperance is destructive of health; evil examples are destructive to the morals of youth.
(n.) One who destroys; a radical reformer; a destructionist.
Example Sentences:
(1) But soon after aid workers departed, barrel bombs dropped by Syrian helicopters caused renewed destruction.
(2) High mortality, severe destruction of pancreatic B-cells and presence of sporadic mononuclear infiltrations in islets and around excretory ducts were observed.
(3) Lung metastases leading to death were observed in one patient with small-cell osteosarcoma despite complete destruction of the primary tumor by preoperative chemotherapy.
(4) Since alkaline phosphatase, a glycoprotein, is not affected, the destruction is selective and presumably involves only the most exposed membrane components.
(5) Intravenous urography revealed destruction of the right kidney resembling Wilms tumor.
(6) Lawmakers across the globe are beginning to recognize the need to deter this destructive conduct.
(7) Finally, the uptake was completely abolished by prior mechanical or osmotic destruction of the intima.
(8) The weapon is 13 metres long, weighs 60 tonnes and can carry nuclear warheads with up to eight times the destructive capacity of the bombs that hit Hiroshima and Nagasaki in the second world war.
(9) While a clearcut relationship cannot be established between heavy metal music and destructive behavior, evidence shows that such music promotes and supports patterns of drug abuse, promiscuous sexual activity, and violence.
(10) Quite the contrary, in cases of higher nervous activity disturbances, destruction of the organelles and desintegration of spine apparatuses is clearly pronounced.
(11) Granule cell destruction began early, and was widespread by 2 days in vitro, when oligodendrocyte destruction also began in treated cultures.
(12) The ferrochelatase-inhibitory activity, porphyrin-inducing activity, and cytochrome P-450- and heme-destructive effects of a variety of analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) were studied in chick embryo liver cells.
(13) A simple technique that consists of curetting the subcutaneous tissue in the necrotic area of the lesion, to prevent the local destructive actions of the toxin, is described.
(14) The high proteolytic activity of BCC demonstrated in this study may be an important factor in the proliferative, invasive and destructive behaviour of this tumour.
(15) North Korea has produced tons of propaganda films that portray America’s destruction.
(16) The object of these studies was to investigate whether destruction of the renal medulla in normal rats would alter vascular capacitance.
(17) We simply do whatever nature needs and will work with anyone that wants to help wildlife.” His views might come as a surprise to some of the RSPB’s 1.1 million members, who would have been persuaded by its original pledge “to discourage the wanton destruction of birds”; they would equally have been a surprise to the RSPB’s detractors in the shooting world.
(18) The tissue destructive process is slower in older than in younger people, and the prognoses in correctly treated cases is good.
(19) Although these two destructive entities are completely different in many respects, they share a common denominator: the initial lesions are brought about by an aggregate of bacteria known as plaque.
(20) It is concluded that the massive destruction of the normal anatomy in the lateral semicircular canal may be the morphological basis of a functional endolymphatic fistula for drainage of the endolymphatic hydrops.
Disruptive
Definition:
(a.) Causing, or tending to cause, disruption; caused by disruption; breaking through; bursting; as, the disruptive discharge of an electrical battery.
Example Sentences:
(1) 62.1% were from disrupted families (39.5% divorced, 12.9% remarried, and 9.7% widowed).
(2) Immunocytochemistry was used to visualize cytoskeletal structures and to assay selective disruption of neurofilaments by acrylamide.
(3) Sepsis resulted from intravenous absorption through inflamed or disrupted urothelium.
(4) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(5) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(6) This would disrupt and prevent Isis from maintaining stable and reliable sources of income.
(7) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
(8) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
(9) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(10) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(11) Displacement of the surface of the cornea of bovine eyes after disruption of intact structures was investigated by means of holographic interferometry.
(12) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
(13) The samples are first disrupted by sonication and the insoluble proteins concentrated by high-speed centrifugation.
(14) Electron microscopic observations of the masseter nerve in the aged cats revealed a disruption of the myelin sheaths and a pronounced increase in collagen fibers in the endoneurium and perineurium.
(15) Light microscopy of both apneics and snorers revealed mucous gland hypertrophy with ductal dilation and focal squamous metaplasia, disruption of muscle bundles by infiltrating mucous glands, focal atrophy of muscle fibers, and extensive edema of the lamina propria with vascular dilation.
(16) We propose that, for a GC base pair in B conformation, there are two amino proton exchangeable states--a cytosine amino proton exchangeable state and a guanine amino proton exchangeable state; both require the disruption of only the corresponding interbase H bond.
(17) No signs of the blood-brain barrier disruption were observed.
(18) Pupils who disrupt the learning of their classmates are dealt with firmly and, in many cases, a short suspension is an effective way of nipping bad behaviour in the bud."
(19) On histopathologic examination there were microabscesses in the inner choroid and subretinal space, disrupting the outer retina but sparing the inner retina.
(20) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.