(v. t.) To make worse; to make inferior in quality or value; to impair; as, to deteriorate the mind.
(v. i.) To grow worse; to be impaired in quality; to degenerate.
Example Sentences:
(1) It is followed by rapid neurobehavioral deterioration in late infancy or early childhood, a developmental arrest, plateauing, and then either a course of retarded development or continued deterioration.
(2) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(3) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(4) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(5) This suggests that there was a deterioration of the vasoconstrictor response and indicated a possible effect of heat at the receptor or effector level.
(6) Four patients had previously been diverted and the other six were reconstructed because of intractable incontinence or deteriorating renal function.
(7) Finally, these cases support the existence of a therapeutic upper limit for desipramine plasma concentrations, above which clinical deterioration occurs.
(8) In view of the high mortality every clinical deterioration of patients with cirrhosis should alert the physician of the presence of SBP.
(9) The authors present a boy with a sudden onset a large intracranial hematoma causing rapid neurologic deterioration.
(10) The data suggest late hemodynamic deterioration after 48 hours of IABC.
(11) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(12) The dilemma focuses on whether the obliteration or removal of the cystic areas will benefit or cause further deterioration of the patient's condition.
(13) Bacteriuria was not associated with deteriorating renal function determined by serial plasma creatinine estimations.
(14) The deteriorating situation would worsen if ministers pressed ahead with another controversial Lansley policy – that of abolishing the cap on the amount of income semi-independent foundation trust hospitals can make by treating private patients.
(15) During a postoperative follow-up period of 1 to 3 years, no further deterioration has been observed and magnetic resonance studies have demonstrated a space filled with cerebrospinal fluid (CSF) around the lumbosacral cord.
(16) Use of sunglasses that block all ultraviolet radiation and severely attenuate high-energy visible radiation will slow the pace of ocular deterioration and delay the onset of age-related disease, thereby reducing its prevalence.
(17) Sechin warned the west earlier this week that expanding sanctions over Russia's annexation of Ukraine's Crimea region would only make the political situation deteriorate further, according to Reuters.
(18) Rates of clinical deterioration and frequencies of attacks were not significantly different between treated and control groups.
(19) In a follow-up of 17 HIV-positive subjects, nine presented deteriorated reflexes in the tests and higher IgG immune complex levels.
(20) However, these good results deteriorated on longer follow-up and were not expected to be permanent.
Exacerbate
Definition:
(v. t.) To render more violent or bitter; to irriate; to exasperate; to imbitter, as passions or disease.
Example Sentences:
(1) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(2) In patients with acute exacerbations of chronic obstructive pulmonary disease, although either sympathomimetic or anticholinergic therapy provides bronchodilatation, no further benefit could be demonstrated from combination therapy.
(3) We report a case of chronic recurrent polymyositis associated with increasing antibody titers of coxsackievirus A9 in serum during clinical exacerbations.
(4) The data indicate that activated helper T cells are required and sufficient to give rise to the inflammatory infiltrates that are characteristic of the inflammations and exacerbations in human rheumatoid arthritis.
(5) The development of renal insufficiency during enalapril therapy may be exacerbated by concomitant diuretic therapy and should raise the suspicion of underlying transplant renal-artery stenosis.
(6) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(7) The utility of a life charting approach is emphasized in delineating past and present course of illness, considering the relevance of cycling pattern and past treatment efficacy in selection of present pharmacological interventions, and helping to formulate a multifactorial concept of the interplay of biological and psychosocial factors in the evolution or exacerbation of mood disorders.
(8) Endotoxins in plasma were monitored during treatment in 18 patients hospitalised for acute exacerbation of Crohn's disease: systemic endotoxaemia was found on admission in all but one.
(9) Exacerbation of inflammation due to repeated traumatization of the oesophagus wall was accompanied by proliferation of the epithelial layers.
(10) Pyoderma gangrenosum is a poorly understood disease characterized by exacerbations and remissions of morphologically unique skin ulcers.
(11) A complex scheme of prophylaxis of exacerbation and progression of chronic bronchopulmonary diseases in children was developed.
(12) The clinical aspects with remission and exacerbation are discussed.
(13) We designed the present study to evaluate the efficacy and safety of cefaclor in the treatment of acute exacerbations of chronic bronchitis in cigarette smokers.
(14) It was demonstrated that neither enflurane nor halothane exacerbates a pre-existing susceptibility to seizure activity and that both these inhalation anaesthetics are suitable for cases suffering from cerebral convulsive disorders.
(15) We conclude that myoglobinuria, of a degree insufficient to cause renal failure itself, can interact with renal ischemia to significantly exacerbate the renal damage produced.
(16) These lymph node reactions could have likely been a part of the so called early exacerbation.
(17) Hyperglycemia exacerbates neurologic damage in clinical and experimental central nervous system ischemia.
(18) Anticoagulation may exacerbate possible tendencies for an ischemic infarction to become hemorrhagic.
(19) (4) Symptoms are exacerbated by a research ward that is disruptive to the community.
(20) This injury was exacerbated to grade 4 (p less than 0.05) following reperfusion but was almost completely healed 24 h later.