(n.) The process of growing worse, or the state of having grown worse.
Example Sentences:
(1) It is followed by rapid neurobehavioral deterioration in late infancy or early childhood, a developmental arrest, plateauing, and then either a course of retarded development or continued deterioration.
(2) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(3) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(4) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(5) This suggests that there was a deterioration of the vasoconstrictor response and indicated a possible effect of heat at the receptor or effector level.
(6) Four patients had previously been diverted and the other six were reconstructed because of intractable incontinence or deteriorating renal function.
(7) Finally, these cases support the existence of a therapeutic upper limit for desipramine plasma concentrations, above which clinical deterioration occurs.
(8) In view of the high mortality every clinical deterioration of patients with cirrhosis should alert the physician of the presence of SBP.
(9) The authors present a boy with a sudden onset a large intracranial hematoma causing rapid neurologic deterioration.
(10) The data suggest late hemodynamic deterioration after 48 hours of IABC.
(11) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(12) The dilemma focuses on whether the obliteration or removal of the cystic areas will benefit or cause further deterioration of the patient's condition.
(13) Bacteriuria was not associated with deteriorating renal function determined by serial plasma creatinine estimations.
(14) The deteriorating situation would worsen if ministers pressed ahead with another controversial Lansley policy – that of abolishing the cap on the amount of income semi-independent foundation trust hospitals can make by treating private patients.
(15) During a postoperative follow-up period of 1 to 3 years, no further deterioration has been observed and magnetic resonance studies have demonstrated a space filled with cerebrospinal fluid (CSF) around the lumbosacral cord.
(16) Use of sunglasses that block all ultraviolet radiation and severely attenuate high-energy visible radiation will slow the pace of ocular deterioration and delay the onset of age-related disease, thereby reducing its prevalence.
(17) Sechin warned the west earlier this week that expanding sanctions over Russia's annexation of Ukraine's Crimea region would only make the political situation deteriorate further, according to Reuters.
(18) Rates of clinical deterioration and frequencies of attacks were not significantly different between treated and control groups.
(19) In a follow-up of 17 HIV-positive subjects, nine presented deteriorated reflexes in the tests and higher IgG immune complex levels.
(20) However, these good results deteriorated on longer follow-up and were not expected to be permanent.
Diminution
Definition:
(n.) The act of diminishing, or of making or becoming less; state of being diminished; reduction in size, quantity, or degree; -- opposed to augmentation or increase.
(n.) The act of lessening dignity or consideration, or the state of being deprived of dignity; a lowering in estimation; degradation; abasement.
(n.) Omission, inaccuracy, or defect in a record.
(n.) In counterpoint, the imitation of, or reply to, a subject, in notes of half the length or value of those the subject itself.
Example Sentences:
(1) Age, histological type, number or location of the index diminutive polyps, were not associated with proximal lesions.
(2) The rate of removal of exogenous PGE2 in the hind limb circulation was not influenced by HC, suggesting that the diminution of PG release by HC results from the suppression of PG generation rather than from the enhancement of degradation.
(3) Incubation of freshly isolated rat hepatocytes with highly purified radiolabeled rat transferrin in weakly buffered medium in the presence of 10 mM ethanol resulted in a marked diminution of iron uptake by these cells, associated with a greater pH depression than in ethanol-free control studies.
(4) The effect was more pronounced in those patients with a greater basal excretion of THP and in those with a more significant diminution of their bone mass.
(5) After intact, cycling female mice received subcutaneous injections of antipain and leupeptin for 16 days, their uteri showed significant diminution in weight and total DNA when compared to untreated controls.
(6) The fibrosis of the gastric wall with motility disturbances, and the diminution of acid and pepsin production from damage to the glandular elements, would weigh against the addition of a vagotomy to the drainage procedure.
(7) The content of membrane lipids also diminished continuously up to 90 years of age, when a marked diminution in level of gangliosides and cerebrosides occurred, a result indicating a rapid reduction in amount of neuronal membranes and myelin.
(8) The tonic influences were expressed in an increase in the amplitude parameters of the responses of the visual cortex in conditions of the formation in the posterolateral nucleus of the thalamus of a focus of heightened excitability (anode polarization), and their perceptible diminution with potassium depression in this nucleus.
(9) Large loads of aspartate cause 20% diminution of glutathione in outer cortex, due entirely to changes in proximal tubule segments.
(10) Rabbits immunized with the flagella developed an immune response to the flagella but showed no statistically significant prolongation of incubation time or diminution of lesion severity when challenged intradermally with 4 X 10(3) Treponema pallidum organisms.
(11) Major changes include an early diminution in myofibrillar density, accompanied by a small reduction in mitochondrial density.
(12) Simultaneous treatment with both drugs resulted in a decrease in the quantity of immune complexes and a diminution of the migration inhibition.
(13) The results presented in this report suggest that the diminution of interphase cytoplasmic microtubules in tumor cells is probably due to the deficiency of microtubule organizing mechanism in interphase tumor cells.
(14) Animals irradiated with 1 Gy showed no diminution in plasma and ileal DAO activities through Day 13 relative to nonirradiated controls.
(15) Response to reimmunization was characterized by a significant acceleration and diminution of skin response, but not to the degree seen in an equivalent group who had received their primary immunization percutaneously.
(16) During the operation and the postoperative period various hemorheological and hemostasiological alterations acquire clinical significance: 1. hyperreagibility of platelets with increased aggregation and adhesion tendency 2. changes in fibrinogen, albumin, and globulin concentrations, which affect viscosity and red cell aggregation 3. impairment of red cell deformability 4. increase in clotting factors 5. disturbance of fibrinolysis characterized by diminution of plasmatic plasmin and increase in antiplasmin activity In addition, anesthetic techniques have also been shown to affect hemorheological and hemostasiological parameters.
(17) In dilute solution this is indeed observed, and the diminution in tetramer concentration when 30% of normal spectrin is replaced by alpha beta' dimers, amounts to only a small proportion.
(18) In contrast to acidosis induced in vivo, mitochondria from normal rats subjected to a diminution in medium pH, either by manipulation of HCO3 concentration or PCO2, significantly decrease NH3 production.
(19) All individuals manifested a marked diminution of CD4+ cells.
(20) Flow cytometric determination of DNA content in R3327AT-3 cells treated in vitro indicated a selective diminution of cells in the G2 and M phases of the cell cycle.