What's the difference between determination and efficacy?

Determination


Definition:

  • (n.) The act of determining, or the state of being determined.
  • (n.) Bringing to an end; termination; limit.
  • (n.) Direction or tendency to a certain end; impulsion.
  • (n.) The quality of mind which reaches definite conclusions; decision of character; resoluteness.
  • (n.) The state of decision; a judicial decision, or ending of controversy.
  • (n.) That which is determined upon; result of deliberation; purpose; conclusion formed; fixed resolution.
  • (n.) A flow, rush, or tendency to a particular part; as, a determination of blood to the head.
  • (n.) The act, process, or result of any accurate measurement, as of length, volume, weight, intensity, etc.; as, the determination of the ohm or of the wave length of light; the determination of the salt in sea water, or the oxygen in the air.
  • (n.) The act of defining a concept or notion by giving its essential constituents.
  • (n.) The addition of a differentia to a concept or notion, thus limiting its extent; -- the opposite of generalization.
  • (n.) The act of determining the relations of an object, as regards genus and species; the referring of minerals, plants, or animals, to the species to which they belong; classification; as, I am indebted to a friend for the determination of most of these shells.

Example Sentences:

  • (1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
  • (2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
  • (3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
  • (5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
  • (6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
  • (7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
  • (8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
  • (9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
  • (10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
  • (11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
  • (15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
  • (16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
  • (18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
  • (20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.

Efficacy


Definition:

  • (n.) Power to produce effects; operation or energy of an agent or force; production of the effect intended; as, the efficacy of medicine in counteracting disease; the efficacy of prayer.

Example Sentences:

  • (1) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
  • (2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
  • (3) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
  • (4) These findings raise questions regarding the efficacy of medical school curriculum in motivating career choices in primary care.
  • (5) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
  • (6) In patients who had undergone gastric operations, the efficacy of a parenteral rehabilitation with plasma, human albumin and Aminofusin L forte was determined by assessing the extravascular albumin pool.
  • (7) It is especially efficacious in evaluating patients with cystic lesions, especially those with complex cysts not clearly of water density.
  • (8) The efficacies of pefloxacin, fosfomycin, and both of these agents in combination against methicillin-resistant Staphylococcus aureus were assessed in a rat endocarditis model.
  • (9) It is concluded that extradural adrenaline does not usefully reduce systemic absorption of 0.5% bupivacaine, but may improve its efficacy in extradural anaesthesia for elective Caesarean section.
  • (10) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
  • (11) We evaluated the safety and efficacy of a conjugate vaccine that links the H. influenzae type b capsular polysaccharide to the outer-membrane protein complex (OMPC) of Neisseria meningitidis serogroup B.
  • (12) Addition of IL7 either alone, or in combination with low doses of IL2, resulted in the generation of CTL with significantly (6-8-fold) enhanced therapeutic efficacy in vivo.
  • (13) The efficacy of the process is dependent on immersion medium, while the degree of surrounding tissue damage is dependent on energy dose.
  • (14) However, self-efficacy (defined as confidence in being able to resist the urge to drink heavily) assessed at intake of treatment, was strongly associated with the level of consumption on drinking occasions at follow-up.
  • (15) The objective of this work was to determine the efficacy of an endoscopic approach coupled to a Nd:YAG laser fiber in performing arytenoidectomy.
  • (16) and (4) Compared to the instruction provided by instructors from other medical and academic disciplines, do paediatric residents perceive differences in the teaching efficacy and clinical relevance of instruction provided by paediatricians?
  • (17) A prospective randomized trial involving 64 patients with bleeding peptic ulcers was performed to assess the efficacy of two modalities of injection therapy.
  • (18) A randomised double-blind trial comparing this preparation with a so-called 'shotgun' combination containing 0.05% betamethasone 17-valerate, 0.1% gentamicin, 1.0% tolnaftate and 1.0% clioquinol in 288 patients in the Philippines resulted in a better efficacy for the diflucortolone preparation in the 80 patients with bacterially or mycotically infected skin diseases.
  • (19) With attention to proper performance and patient selection, spinal and epidural anaesthesia are safe and efficacious options when choosing anaesthetic technique.
  • (20) How useful is the technique for evaluating therapeutic efficacy?