(v. t.) To fix the boundaries of; to mark off and separate.
(v. t.) To set bounds to; to fix the determination of; to limit; to bound; to bring to an end; to finish.
(v. t.) To fix the form or character of; to shape; to prescribe imperatively; to regulate; to settle.
(v. t.) To fix the course of; to impel and direct; -- with a remoter object preceded by to; as, another's will determined me to this course.
(v. t.) To ascertain definitely; to find out the specific character or name of; to assign to its true place in a system; as, to determine an unknown or a newly discovered plant or its name.
(v. t.) To bring to a conclusion, as a question or controversy; to settle authoritative or judicial sentence; to decide; as, the court has determined the cause.
(v. t.) To resolve on; to have a fixed intention of; also, to cause to come to a conclusion or decision; to lead; as, this determined him to go immediately.
(v. t.) To define or limit by adding a differentia.
(v. t.) To ascertain the presence, quantity, or amount of; as, to determine the parallax; to determine the salt in sea water.
(v. i.) To come to an end; to end; to terminate.
(v. i.) To come to a decision; to decide; to resolve; -- often with on.
Example Sentences:
(1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
(5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
(6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
(10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
(11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
(17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.
Discern
Definition:
(v. t.) To see and identify by noting a difference or differences; to note the distinctive character of; to discriminate; to distinguish.
(v. t.) To see by the eye or by the understanding; to perceive and recognize; as, to discern a difference.
(v. i.) To see or understand the difference; to make distinction; as, to discern between good and evil, truth and falsehood.
(v. i.) To make cognizance.
Example Sentences:
(1) However, no evidence could be discerned to support its validity as a measure of a patient's treatment outcome.
(2) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(3) This was apparent by standard flux techniques only in low (65 mM) Na solutions, but was readily discernible in normal Na (125 mM) with the "lanthanum-residual" technique.
(4) By this method two types of granules have been discerned according to their different contrasts.
(5) Several stages in its histogenesis may be discerned: I. focal necroses of hepatic cells associated with their invasion with lister Listeria; 2. appearance of cellular elements around the foci of necroses with subsequent formation of granulemas consisting mainly of leucocytes and lymphoid cells; 3. development of necrobiotic changes in the central areas of granulemas with concomitance of exudative processes; 4. organization of necrotic foci with subsequent scarring.
(6) Significant increment in lipid peroxidation was discernible in brain, liver and muscle.
(7) While there's no discernible forró influence in the dreamy 80s indie-guitar music of Fortaleza's Cidadão Instigado, they do take influence from popular local style brega, a 1970s and 80s Brazilian romantic pop music.
(8) Furthermore, individual AgNOR dots were much more readily discerned in cell imprints than in sections, and this appears to be the method of choice if pathologists wish to at least approach absolute rather than relative AgNOR counts.
(9) In order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken.
(10) Changes in the secretory process were discernible as of day 1 in all three tumors, with a dramatic reduction of exocytosis and intracellular accumulation of PRL-immunoreactive granules.
(11) The advent of cyclosporine A provides the dermatologist with a new therapeutic strategem in the management of psoriasis, although the long-term safety of such interventional therapy remains to be discerned.
(12) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(13) However, by phase microscopy, no changes are discernible within the first 12-18 h. Since the primary NGF receptor appears to be a membrane receptor, it seemed likely that some of the initial responses to the factor may be surface related.
(14) Whereas no discernible differences on survival were documented on a long-term basis, when patient who ultimately recurred in each group were compared, a substantial and statistically significant prolongation of the free-of-disease interval from surgery to recurrence and of survival from recurrence to death are revealed.
(15) The results suggest that TGF-beta 1 has powerful anti-inflammatory effects, mimicking in some respects the beneficial effects of immunosuppressive drugs in these experimental models of autoimmune disease, but without discernable adverse effects.
(16) Temporal differences in the expression of sugar-binding proteins and different patterns of staining of the component cell types of human placenta were discerned, especially pronounced for alpha-fucoside-specific binding in the trophoblast and alpha-glucoside-specific binding in fetal and maternal macrophages.
(17) They’re all basically the same, but the tiny, barely discernible differences between them consume vast amounts of energy and generate heartache for everyone involved.
(18) Judged radiographically, partial obliteration (pulp chamber not discernible, root canal markedly narrowed but clearly visible) had occurred in 44 teeth (36%).
(19) Starch ingestion had no discernible effect on postprandial lipemia.
(20) We conclude that long-term prophylaxis with TMP-SMZ does not produce discernable hematologic, renal, or hepatic toxicity in renal transplant recipients nor does it augment nephrotoxicity with cyclosporine or increase the risk of rejection.