What's the difference between determine and predetermine?

Determine


Definition:

  • (v. t.) To fix the boundaries of; to mark off and separate.
  • (v. t.) To set bounds to; to fix the determination of; to limit; to bound; to bring to an end; to finish.
  • (v. t.) To fix the form or character of; to shape; to prescribe imperatively; to regulate; to settle.
  • (v. t.) To fix the course of; to impel and direct; -- with a remoter object preceded by to; as, another's will determined me to this course.
  • (v. t.) To ascertain definitely; to find out the specific character or name of; to assign to its true place in a system; as, to determine an unknown or a newly discovered plant or its name.
  • (v. t.) To bring to a conclusion, as a question or controversy; to settle authoritative or judicial sentence; to decide; as, the court has determined the cause.
  • (v. t.) To resolve on; to have a fixed intention of; also, to cause to come to a conclusion or decision; to lead; as, this determined him to go immediately.
  • (v. t.) To define or limit by adding a differentia.
  • (v. t.) To ascertain the presence, quantity, or amount of; as, to determine the parallax; to determine the salt in sea water.
  • (v. i.) To come to an end; to end; to terminate.
  • (v. i.) To come to a decision; to decide; to resolve; -- often with on.

Example Sentences:

  • (1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
  • (2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
  • (3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
  • (5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
  • (6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
  • (7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
  • (8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
  • (9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
  • (10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
  • (11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
  • (15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
  • (16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
  • (18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
  • (20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.

Predetermine


Definition:

  • (v. t.) To determine (something) beforehand.
  • (v. t.) To doom by previous decree; to foredoom.
  • (v. i.) To determine beforehand.

Example Sentences:

  • (1) When subjects centered themselves actively, or additionally, contracted trunk flexor or extensor muscles to predetermined levels of activity, no increase in trunk positioning accuracy was found.
  • (2) Employed method of observation gave quantitative information about the influence of odours on ratios of basic predeterminate activities, insect distribution pattern and their tendency to choose zones with an odour.
  • (3) The duration of electrophoresis was based on the migration of a marker dye for a predetermined distance.
  • (4) Ventricular fibrillation was then induced and, after predetermined downtimes ranging from 5 to 60 minutes, thoracotomy was performed, and open-chest bimanual cardiac massage was started.
  • (5) Anesthetized, intubated kittens were subjected to one of two procedures: (1) insertion of a suction catheter to a predetermined distance and withdrawal with or without the application of suction or (2) insertion of the catheter until resistance was met and withdrawal with or without the application of suction.
  • (6) Minute ventilation (VE) was kept constant at a predetermined individual level during all treatments.
  • (7) Thus, it appears that the increased expression of the regulatory MLC2 gene in SHR atrial cells is a predetermined event, which, most likely, participates in functional adaptation of the myocardium in response to pressure overload and subsequent hypertrophy.
  • (8) Furthermore, the minimal actual treatment differences that can be detected with a reasonable (80%) probability at a predetermined (5%) significance level using a crossover design were estimated for different electrophysiologic variables.
  • (9) Each student conducted a medication-history interview with one of two simulated patients who presented a predetermined history; interviews were videotaped from behind a one-way mirror.
  • (10) The %s of fibroblasts, PMN's lymphocytes, plasma cells and macrophages were estimated in a predetermined standardized area close to the apical termination of the junctional epithelium.
  • (11) Under in vitro inhibition of alpha-glucosidasic activity by glucose in hemolymph of Bee prenymphas, the reaction order (n) (predetermined according to the initial natural glycemia) decreases with increasing inhibitor concentration and the affinity constant between enzyme and substrate undergoes lower variations than in other cases where (n) does not change.
  • (12) The effect of indomethacin administration on the mortality rate of brain-injured rats was studied in four groups of animals subjected to a level of injury with a fluid-percussion apparatus predetermined to cause 50% mortality (50% lethal dose, or LD50).
  • (13) To estimate the mean cardiac output, at least two measurements should be made at predetermined points of the ventilatory cycle.
  • (14) Microliter volumes of cell suspension were placed directly onto a computer-controlled cryostage and cooled to a predetermined subzero temperature.
  • (15) A genetic procedure is directed for the isolation of chromosomal deletions and duplications with predetermined endpoints.
  • (16) Specific checklists completed by patients and predetermined scoring protocols yielded reliable data and reduced faculty time.
  • (17) "It seems that the Metropolitan police, the CPS [Crown Prosecution Service] and even the court have all colluded to implement a predetermined decision which was made in Washington.
  • (18) Various techniques can be used to deposit the dose accurately in a predetermined intracranial volume.
  • (19) The same brush was then agitated in a SBW vial, which was centrifuged, the cell pellet being smeared over a predetermined area of a slide.
  • (20) Eleven children with severe perennial asthma and a poor clinical response to disodium cromoglycate were studied in a 4-month, double blind trial involving 1 month's treatment with placebo, disodium cromoglycate, betamethasone 17 valerate, and both drugs combined according to a predetermined random design.