What's the difference between determined and pessimistic?

Determined


Definition:

  • (imp. & p. p.) of Determine
  • (a.) Decided; resolute.

Example Sentences:

  • (1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
  • (2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
  • (3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
  • (5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
  • (6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
  • (7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
  • (8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
  • (9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
  • (10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
  • (11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
  • (15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
  • (16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
  • (18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
  • (20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.

Pessimistic


Definition:

  • (a.) Of or pertaining to pessimism; characterized by pessimism; gloomy; foreboding.

Example Sentences:

  • (1) A rather pessimistic wind is blowing over cancer chemotherapy, while a not very objective enthusiasm for second generation immunotherapy is raising its head.
  • (2) We challenge this pessimistic approach, and describe here our experience with seven patients with solid tumors, in whom pericardial effusion was diagnosed; one of them is described in detail.
  • (3) Verbally abused children were more angry and more pessimistic about their future.
  • (4) Has recently sounded pessimistic about the prospects for a full post-Copenhagen treaty: "You should not have too many expectations."
  • (5) Two groups, one institutionalized and the other noninstitutionalized but without formal activities, were described as being disengaged: e.g., withdrawn socially, self-absorbed, as well as powerless, pessimistic, and depressed.
  • (6) It is concluded that the heretofore pessimistic outlook regarding complete quadriplegia is unwarranted and that a more aggressive approach may result in a better functional outcome.
  • (7) "What our study has shown is that this applies similarly to dogs – that a 'glass half full' dog is less likely to be anxious when left alone than one with a more 'pessimistic' nature."
  • (8) "It's like watching a bullfight," says one Conservative backbench pessimist.
  • (9) The agency hopes it can later extend the work to urban rivers outside London, but is pessimistic that parts of the Fleet might one day be released to public view.
  • (10) It is a totally unrealistic, pessimistic vision about what this country can achieve."
  • (11) Rehabilitation of patients with chronic respiratory disease has tended to be neglected in the past, partly because of a generally pessimistic view of their prospects.
  • (12) Another important factor is the lack of motivation shown by attending physicians to detect less obvious cases of alcohol dependence as they feel pessimistic about dealing with this condition.
  • (13) Predictions based on very early assessment are, therefore, often unduly pessimistic.
  • (14) If we’re being pessimistic about it, the whole idea of the euro has been weakened and maybe we’ll look back and see this as the beginning of the end of that ideal.” She reflected a pessimistic feeling among Germans, whether financial experts or ordinary folk on the street, that the whole of Europe had taken a battering over the negotiations, one from which it would take time to recover; and the strong belief that the very same politicians would once again find themselves in a huddle over the same issue a few months down the line.
  • (15) A substantial number of people who start small businesses have no qualifications beyond secondary school, he says, and, worse, may have no technical or business management training Peter Strong, of the Small Business Association , is less pessimistic.
  • (16) The estimated overall risk difference remained negative even when all patients in the sclerotherapy group with an unknown survival status were pessimistically considered dead at the end of the follow-up period.
  • (17) In the pessimistic case, UK income falls by 3.1%, or £50bn a year.” More business leaders lined up on Thursday to voice their concerns that the UK economy will be a significant casualty of a decision to leave the EU, including Sir Martin Sorrell, chief executive of the advertising firm WPP.
  • (18) It is a measure of how pessimistic the MPC has become that even a one percentage point lowering in the assumed policy rate profile was deemed insufficient to offset the bad news on demand.
  • (19) The only thing maintaining the flow of migrants is that nobody reads the Daily Mail until they arrive, and only then do they realise how coarse and brutal our politics have become, how pessimistic.
  • (20) Women and more pessimistic parents were more distressed.