(1) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(2) Samaras said: A "Grexit", as it is called, would be devastating for Greece and detrimental to Europe.
(3) The striking improvements in carbohydrate and lipid metabolism in diabetic and non-diabetic Aborigines after a temporary reversion to a traditional hunter-gatherer lifestyle highlight the potentially reversible nature of the detrimental effects of lifestyle change, particularly in young people who have not yet developed diabetes.
(4) A murine model system was developed to determine whether ionizing radiation has a detrimental influence on thymic epithelium, cell function.
(5) The aim of this study was determine if functional adaptation of NHP and HB position to these detrimental conditions could be observed, using Bonferonni probabilities, in a cephalometric comparison of 38 SAS adults in the wakeful state and a control group of 38 healthy adults.
(6) Together, they dispel the myth that changing initial responses more often is detrimental than beneficial.
(7) Also, studies on the simulated cumulative effect of background radiation during storage failed to find any detrimental effect when embryos were exposed to the equivalent of about 2000 years of background radiation.
(8) The author then describes new approaches to improving the vocational integration of persons with epilepsy, by focussing on the one hand on extending the range of occupational assessment, and the adoption of new job placement assessment, and the adoption of new job placement strategies on the other, which concurrently seek to influence those factors that are detrimental to the occupational outlook of the person with a seizure disorder (notably frequent seizures, psychiatric problems, low educational levels, negative employer attitudes).
(9) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(10) Alternatively, increasing this ratio may permit embryos to reduce the concentration of a substance detrimental to their growth.
(11) Because NMDA receptor antagonists impede certain kinds of learning, and because motor recovery after sensorimotor cortex injury in the rat is dependent on post-lesion experience, we hypothesized that treatment with MK-801 after focal brain injury would be detrimental.
(12) Student participation in school-based suicide prevention programs, however, was associated with a detrimental effect on state teenage suicide rates.
(13) Aggressive or improper toothbrushing techniques may have a detrimental impact on the gingiva.
(14) On this basis we tried to change the milieu on a 26-bed therapeutic community ward which proved to have pseudo-groups and a detrimental ward atmosphere.
(15) In a pediatric critical care environment with skilled ongoing nursing care, the axillary artery can be used as a site for intraarterial monitoring in pediatric patients without a detrimental effect on concurrent or future blood pressure monitoring.
(16) These data suggest that sCR1 inhibits the Arthus reaction by interrupting the activation of the C cascade, hence limiting the detrimental immune complex-induced tissue damage in vivo.
(17) Unreasonable expectations and expansion of the health sector have spawned counterproductive effects which are to some extent detrimental to public health.
(18) Falls among hospitalized patients are common occurrences and can have detrimental effects on patient outcomes.
(19) Nylon drains are available in any operating room, and have no detrimental effects on the grafted skin.
(20) Focal cerebral ischemia initiates multiple detrimental effects in the brain.
Hurtful
Definition:
(a.) Tending to impair or damage; injurious; mischievous; occasioning loss or injury; as, hurtful words or conduct.
Example Sentences:
(1) He missed the start of the season while rehabbing from last season's ankle injury, played exactly six games with the Los Angeles Lakers before getting hurt again and even if he's healthy he may still sit the game out .
(2) Here's a certainty: When you play out your personal dramas, hurt and self-interest in the media, it's a confection.
(3) Israel’s president has told his Mexican counterpart that he was “sorry for the hurt” over a tweet in which the prime minister, Benjamin Netanyahu, appeared to praise Donald Trump’s plans to build a wall on the US-Mexican border.
(4) No one was seriously hurt but the road was closed north and south at 2.15am, and police have asked drivers to find alternatives.
(5) My unreliable BlackBerry was hurting business," she said.
(6) I watched as she made the briefest eye contact with me on their way back, the flicker of hurt and sadness in her eyes reflecting mine, before the shutters came down.
(7) Target’s data breach in 2013 exposed details of as many as 40m credit and debit card accounts and hurt its holiday sales that year.
(8) In the latest survey to suggest that struggles in the eurozone and geopolitical tensions are hurting exporters, the CBI said manufacturing was the weakest part of the economy in the three months to October.
(9) Photograph: Guardian Environmental activists now argue that if Obama fails to recognise that anger and block the pipeline, he could hurt his chances in the 2012 elections.
(10) Here's what you need to know Read more Speaking to Guardian Australia ahead of the Festival of Dangerous Ideas in Sydney, Krugman, a renowned columnist at the New York Times , predicted the slowing Chinese economy would hurt Australia, but said the country should not get “too hysterical” about it.
(11) New employment data today suggested that hurricane Sandy is hurting already tenuous US job growth.
(12) It hurts indigenous Irish businesses whose main trade links are with the UK.
(13) A long spell of ultra-low interest rates has not driven a rise in inequality in the UK, the deputy governor of the Bank of England has said, rebuffing criticism that central bank policy had hurt some households.
(14) During interviews, married couples experiencing infertility reported emotional reactions such as sadness, depression, anger, confusion, desperation, hurt, embarrassment, and humiliation.
(15) A rocket also caused the first serious Israeli casualty – one of eight people hurt when a fuel tanker was hit at a service station in Ashdod, 20 miles north of Gaza.
(16) Giving power to people – that’s at the heart of what I’m trying to do.” He said the Liberal Democrats had made “serious mistakes” which had hurt them in Thursday’s election, during which the party won eight seats, compared with 57 in 2010.
(17) There was too much hurt and uncontrolled anger when she was in the superior position with the kind of man who could not meet her dependency needs.
(18) Kashyap also told MPs about that weakness in banks across the EU could hurt major players in the UK.
(19) Brown runs four yards, but on that play Stanley Havill gets hurt.
(20) Speaking on BBC Radio 4's Today programme, Tim Lang , professor of food policy at London's City University, said there were deeper structural issues to global food market price rises that politicians were not taking seriously and which were hurting the poor disproportionately.