(1) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(2) Samaras said: A "Grexit", as it is called, would be devastating for Greece and detrimental to Europe.
(3) The striking improvements in carbohydrate and lipid metabolism in diabetic and non-diabetic Aborigines after a temporary reversion to a traditional hunter-gatherer lifestyle highlight the potentially reversible nature of the detrimental effects of lifestyle change, particularly in young people who have not yet developed diabetes.
(4) A murine model system was developed to determine whether ionizing radiation has a detrimental influence on thymic epithelium, cell function.
(5) The aim of this study was determine if functional adaptation of NHP and HB position to these detrimental conditions could be observed, using Bonferonni probabilities, in a cephalometric comparison of 38 SAS adults in the wakeful state and a control group of 38 healthy adults.
(6) Together, they dispel the myth that changing initial responses more often is detrimental than beneficial.
(7) Also, studies on the simulated cumulative effect of background radiation during storage failed to find any detrimental effect when embryos were exposed to the equivalent of about 2000 years of background radiation.
(8) The author then describes new approaches to improving the vocational integration of persons with epilepsy, by focussing on the one hand on extending the range of occupational assessment, and the adoption of new job placement assessment, and the adoption of new job placement strategies on the other, which concurrently seek to influence those factors that are detrimental to the occupational outlook of the person with a seizure disorder (notably frequent seizures, psychiatric problems, low educational levels, negative employer attitudes).
(9) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(10) Alternatively, increasing this ratio may permit embryos to reduce the concentration of a substance detrimental to their growth.
(11) Because NMDA receptor antagonists impede certain kinds of learning, and because motor recovery after sensorimotor cortex injury in the rat is dependent on post-lesion experience, we hypothesized that treatment with MK-801 after focal brain injury would be detrimental.
(12) Student participation in school-based suicide prevention programs, however, was associated with a detrimental effect on state teenage suicide rates.
(13) Aggressive or improper toothbrushing techniques may have a detrimental impact on the gingiva.
(14) On this basis we tried to change the milieu on a 26-bed therapeutic community ward which proved to have pseudo-groups and a detrimental ward atmosphere.
(15) In a pediatric critical care environment with skilled ongoing nursing care, the axillary artery can be used as a site for intraarterial monitoring in pediatric patients without a detrimental effect on concurrent or future blood pressure monitoring.
(16) These data suggest that sCR1 inhibits the Arthus reaction by interrupting the activation of the C cascade, hence limiting the detrimental immune complex-induced tissue damage in vivo.
(17) Unreasonable expectations and expansion of the health sector have spawned counterproductive effects which are to some extent detrimental to public health.
(18) Falls among hospitalized patients are common occurrences and can have detrimental effects on patient outcomes.
(19) Nylon drains are available in any operating room, and have no detrimental effects on the grafted skin.
(20) Focal cerebral ischemia initiates multiple detrimental effects in the brain.
Wrong
Definition:
() imp. of Wring. Wrung.
(a.) Twisted; wry; as, a wrong nose.
(a.) Not according to the laws of good morals, whether divine or human; not suitable to the highest and best end; not morally right; deviating from rectitude or duty; not just or equitable; not true; not legal; as, a wrong practice; wrong ideas; wrong inclinations and desires.
(a.) Not fit or suitable to an end or object; not appropriate for an intended use; not according to rule; unsuitable; improper; incorrect; as, to hold a book with the wrong end uppermost; to take the wrong way.
(a.) Not according to truth; not conforming to fact or intent; not right; mistaken; erroneous; as, a wrong statement.
(a.) Designed to be worn or placed inward; as, the wrong side of a garment or of a piece of cloth.
(adv.) In a wrong manner; not rightly; amiss; morally ill; erroneously; wrongly.
(a.) That which is not right.
(a.) Nonconformity or disobedience to lawful authority, divine or human; deviation from duty; -- the opposite of moral right.
(a.) Deviation or departure from truth or fact; state of falsity; error; as, to be in the wrong.
(a.) Whatever deviates from moral rectitude; usually, an act that involves evil consequences, as one which inflicts injury on a person; any injury done to, or received from; another; a trespass; a violation of right.
(v. t.) To treat with injustice; to deprive of some right, or to withhold some act of justice from; to do undeserved harm to; to deal unjustly with; to injure.
(v. t.) To impute evil to unjustly; as, if you suppose me capable of a base act, you wrong me.
Example Sentences:
(1) In this book, he dismisses Freud's idea of penis envy - "Freud got it spectacularly wrong" - and said "women don't envy the penis.
(2) But this is to look at the outcomes in the wrong way.
(3) It is not that the concept of food miles is wrong; it is just too simplistic, say experts.
(4) "But this is not all Bulgarians and gives a totally wrong picture of what the country is about," she sighed.
(5) No malignant tumour failed to be diagnosed (100% reliable), the anatomopathological examination of specimens in benign conditions was never wrong (100% reliable).
(6) The Bible treats suicide in a factual way and not as wrong or shameful.
(7) "That attracted all the wrong sorts for a few years, so the clubs put their prices up to keep them out and the prices never came down again."
(8) More than half of carers said they were neglecting their own diet as a result of their caring responsibilities, while some said they were eating the wrong things because of the stress they are under and more than half said they had experienced problems with diet and hydration.
(9) A final experiment confirmed a prediction from the above theory that when recalling the original sequence, omissions (recalling no word) will decrease and transpositions (giving the wrong word) will increase as noise level increases.
(10) Other details showed the wrong patient undergoing a heart procedure, and the wrong patient given an invasive colonoscopy to check their bowel.
(11) Mulholland and others have tried to portray the Leeds case in terms of right or wrong.
(12) And of course, as the articles are shared far and wide across the apparently much-hated web, they become gospel to those who read them and unfortunately become quasi-religious texts to musicians of all stripes who blame the internet for everything that is wrong with their careers.
(13) And I was a little surprised because I said: ‘Doesn’t sound like he did anything wrong there.’ But he did something wrong with respect to the vice-president and I thought that was not acceptable.” So that’s clear.
(14) The fitting element to a Cabrera victory would have been thus: the final round of the 77th Masters fell on the 90th birthday of Roberto De Vicenzo, the great Argentine golfer who missed out on an Augusta play-off by virtue of signing for the wrong score.
(15) "I don't think that people are waiting for the wrong solution."
(16) I can’t hear those wrong notes any more,” she says.
(17) "This crowd of charlatans ... look for one little thing they can say is wrong, and thus generalise that the science is entirely compromised."
(18) Eleven women have died in India and dozens more are in hospital, with 20 listed as critically ill, after a state-run mass sterilisation campaign went horribly wrong.
(19) in horses is imputed to the small numbers of people involved in the work, to the conservation of the authorities responsible for breeding, to the wrong choice of stallions for A.I.
(20) The Sun editor also said his newspaper was wrong to use the word "tran" in a headline to describe a transexual, saying that he felt that "I don't know this is our greatest moment, to be honest".