(n.) A disease which is attended with a persistent, excessive discharge of urine. Most frequently the urine is not only increased in quantity, but contains saccharine matter, in which case the disease is generally fatal.
Example Sentences:
(1) All rats were examined in the conscious, unrestrained state 12 wk after induction of diabetes or acidified saline (pH 4.5) injection.
(2) The main finding of this study is that diabetic adolescents with a high erythrocyte Na,Li countertransport rate have an arterial pressure significantly higher than patients with normal Na,Li countertransport fluxes.
(3) 5 pregnant insulin-dependent diabetics were also studied.
(4) 278 children with bronchial asthma were medically, socially and psychologically compared to 27 rheumatic and 19 diabetic children.
(5) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(6) The difference in HDL and HDL2 cholesterol concentrations between the MI+ and MI- groups or between the MI+ and CHD- groups persisted after adjustment by analysis of covariance for the effect of physical activity, alcohol intake, obesity, duration of diabetes, and glycemic control.
(7) Obesity in the Pimas is familial and has complex relationships with non-insulin-dependent diabetes mellitus, a common disease in this population.
(8) Maternal diabetes and antihistamine use during the last 2 weeks of pregnancy were associated with significantly higher rates of retrolental fibroplasia, whereas toxemia was associated with lower rates.
(9) Treatment for diabetic neuropathy remains inadequate.
(10) Current recommendations regarding contraception in patients with diabetes are not appropriate for the adolescent population and therefore tend to support this phenomenon rather than relieve it.
(11) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
(12) From the present results it is concluded that secretion of extrapancreatic glucagon increased in response to arginine infusion in the diabetic state, both alloxan diabetic dogs and one-week post-pancreatectomized dogs.
(13) The prevalence of diabetes was 36% higher among San Antonio Mexican Americans than among Mexicans in Mexico City; this difference was highly statistically significant (age- and sex-adjusted prevalence ratio 1.36, P = 0.006).
(14) None of the animals injected with either CD4+ or CD8+ T cells became overtly diabetic during the 30 days of observation whereas 8 of 23 mice inoculated with a mixture of the two subsets developed glycosuria and hyperglycemia.
(15) Cytosolic-to-mitochondrial ratios from maximal initial rates after correction for mitochondrial breakage were increased above controls in diabetic hearts for nucleoside diphosphokinase and aspartate aminotransferase.
(16) IgG antibody titres to Coxsackie B1-B6 were measured in 113 insulin-dependent diabetes mellitus (IDDM) patients whose mean age was 12.2 years and mean duration of IDDM was 4.6 years, and in 87 normal sibling controls whose mean age was 13.8 years.
(17) Acute effects of insulin on protein metabolism (whole body and forearm muscle) were simultaneously assessed using doubly labelled (13C15N) leucine in post-absorptive Type I diabetic patients.
(18) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(19) It is suggested that diabetes causes selective changes in the functioning of Gi in adipocyte membranes which removes the tonic GTP-dependent inhibitory function of this G-protein.
(20) Cholera toxin-catalysed ADP-ribosylation identified two forms of Gs alpha-subunits whose labelling was about 4-fold greater in membranes from diabetic animals compared with those from lean animals.
Obesity
Definition:
(n.) The state or quality of being obese; incumbrance of flesh.
Example Sentences:
(1) The difference in HDL and HDL2 cholesterol concentrations between the MI+ and MI- groups or between the MI+ and CHD- groups persisted after adjustment by analysis of covariance for the effect of physical activity, alcohol intake, obesity, duration of diabetes, and glycemic control.
(2) A modification of Mason's vertical banded gastroplasty for morbid obesity is presented, along with experience from 62 treated patients.
(3) These results could be explained by altered tissue blood flow and a decreased metabolic capacity of the liver in obese subjects.
(4) Obesity in the Pimas is familial and has complex relationships with non-insulin-dependent diabetes mellitus, a common disease in this population.
(5) Basal and maximally insulin-stimulated rates of 3-O-methylglucose transport in adipocytes from obese and obese NIDDM subjects were reduced to 50% of the values in cells from normal subjects (P less than 0.05).
(6) The heterogeneity of obesity may be demonstrated by the shape of fat distribution and the prolactin response to insulin hypoglycaemia.
(7) (2) A close correlation between the obesity index and serum GPT was recognized by elevation of the standard partial regression coefficient of serum GPT to obesity index and that of obesity index to serum GPT when the data from all 617 students was analysed in one group.
(8) The inner diameters increased with age in the same way in both obese and control persons, indicating the the former are not protected against osteoporosis in the form of endosteal resorption.
(9) The prognosis was adversely affected by obesity, preoperative flexion contracture of 30 degrees or more, wound-healing problems, wound infection, and postoperative manipulation under general anesthesia.
(10) Airway closure (CV), functional residual capacity (FRC) and the distribution of inspired gas (nitrogen washout delay percentage, NWOD %) and arterial oxygen tension (PaO2) was measured by standard electrodes in eight extremely obese patients before and after weight loss (mean weights 142 and 94 kg, respectively) following intestinal shunt operation.
(11) We conclude that aging alone has little or no effect on the responsiveness to insulin of glucose metabolism in fat cells and that the insulin resistance of adipocytes from obese older rats is due to fat cell hypertrophy, not aging.
(12) The relationships of birth weight and maternal diabetes to the development of obesity were examined at 5-19 yr of age in the offspring of Pima Indian women.
(13) Doctors have blamed rising levels of type 2 diabetes on the growing number of overweight and obese adults.
(14) A patient died after gastric surgery for morbid obesity.
(15) You can get a five-month-old to eat almost anything,” says Clare Llewellyn, lecturer in behavioural obesity research at University College London.
(16) These results emphasize the importance of plasma FFA levels as a correlate of glucose tolerance and suggest that the associations previously reported between obesity, regional body fat distribution, fat cell size and glucose tolerance are, at least partly, mediated by variations in plasma FFA levels.
(17) We conclude that both lean and obese former GDM women have insulin secretion defects.
(18) This study has been designed to evaluate whether duration and severity of obesity can influence left ventricular function response to exercise in obese subjects without other known cardiovascular risk factors such as hypertension, diabetes or hyperlipoproteinemia.
(19) The modifying effect of estrogen receptor status on the relation of obesity to node involvement was apparent in pre- and post-menopausal women.
(20) In addition, insulin tolerance tests were performed on 8 lean and 8 obese subjects before and after starvation.