What's the difference between diamide and diamine?
Diamide
Definition:
(n.) Any compound containing two amido groups united with one or more acid or negative radicals, -- as distinguished from a diamine. Cf. Amido acid, under Amido, and Acid amide, under Amide.
Example Sentences:
(1) In intact cell preparations, diamide produced a slow tonic contraction, consistent with myofibril activation.
(2) Moreover, the accelerated rate of methylglucose uptake produced by diamide treatment is not inhibited by cytochalasin B, an agent that blocks basal and insulin-stimulated methylglucose transport.
(3) The thiol oxidizing agent diamide inhibited both vaso- and bronchoconstriction induced by H2O2, AA, or U-44069.
(4) Liver was the most responsive to these agents in that all 11 chemicals increased MT concentrations in liver, with diethyl maleate, paraquat, and diamide producing 20- to 30-fold increases.
(5) This study deals with the effects of the SH oxidizing agent diamide (diazene dicarboxylic acid bis-(N,N-dimethyl-amide)) on the water-soluble proteins from rabbit lenses.
(6) Following the complete GSH oxidation diamide impaired the turnover of PIP and PA dramatically.
(7) Furthermore, we observed cross-resistance and self-tolerance with three seemingly unrelated stimuli (diamide, heat, and sodium arsenite).
(8) The diamide inhibition was reversible, and H2O2-induced vaso- and bronchoconstriction was almost maximal after 10 min of perfusion with buffer.
(9) After mild treatment of spectrin with 2.5 microM diamide, with formation of an average of only one disulfide bond, we observed a 50% reduction in the ability of protein 4.1 to amplify spectrin-actin binding.
(10) No additive effect was observed when the cells were simultaneously treated with diamide and verapamil.
(11) N-ethylmalemide and diamide irreversibly inhibited endocytosis of all ligands tested, whereas low pH in the cytosol strongly inhibited endocytosis of transferrin and EGF.
(12) A diamide concentration dependent IgG loading of erythrocytes was observed.
(13) These effects increase with diamide concentrations up to 2-2.5 mM and are persistent after removal of the reagent.
(14) Diamide oxidized intracellular glutathione in these cells and produced extensive protein S-thiolation.
(15) In isolated rat pancreatic islets, the effect of diamide and N-ethylmaleimide (NEM) on forskolin- as well as on glucagon-induced elevation of cAMP was studied.
(16) Nutritional supplementation with Mn(II) favored occupancy of the MnSOD active site with manganese and allowed anaerobic accumulation of Mn2-MnSOD in the absence of diamide.
(17) Although NEM substantially potentiated the flow-induced release of prostacyclin (PGI2), probably due to a blockade of the reacylation of arachidonic acid, it inhibited the stimulated release of PGI2, whereas diamide did not significantly affect either release.
(18) A similar increase in the ability of diamide to cause anaerobic biosynthesis of active MnSOD was seen when the production of the MnSOD polypeptide was increased by isopropyl-beta-D-thiogalactopyranoside, in a strain bearing the MnSOD gene under the control of the tac promoter.
(19) Diamide caused anaerobic induction of active MnSOD and this effect was also observed in a glutathione-negative strain.
(20) Flow cytometric analysis of nitrofurantoin-treated spermatozoa showed that nitrofurantoin maintained the sperm disulfides formed by diamide and prevented the reduction of sperm disulfides back to sulfhydryls.
Diamine
Definition:
(n.) A compound containing two amido groups united with one or more basic or positive radicals, -- as contrasted with a diamide.
Example Sentences:
(1) The behaviour of DAO suggests that the enzyme plays an important role in the control of intracellular diamine concentration.
(2) The preservation of diamine oxidase activity during starvation implies a need for the enzyme not related to mucosal proliferation or digestion.
(3) Ornithine decarboxylase (ODC) and diamine oxidase (DAO), enzymes involved in polyamine metabolism, are highly expressed by small bowel enterocytes.
(4) Its penetration into the cells was blocked with the diamines putrescine and cadaverine.
(5) 195, 164 168] concluded that low concentrations of diamines reversed the direction of the proton pump.
(6) When administered in combination with the diamine oxidase inhibitor, aminoguanidine, an almost complete block of histamine metabolism was observed.
(7) In bis-(dichloroacethyl)-octamethylen-diamine (bis-diamine)-induced malformed hearts, localization of HNK-1 immunoreactivity was not remarkably altered in the early embryonic heart.
(8) Free polyamines as well as activity of diamine oxidase were distinctly increased in blood, while concentration of total diamino acids was simultaneously decreased in blood serum of the patients as compared with that of healthy persons.
(9) The substitution of an amino group for methyl one in a diamine increased its inhibitory effect.
(10) The authors suggest a method for simultaneous measurements of the blood serum monoamine oxidase and diamine oxidase activities that permits cut down the time of the blood and substrate incubation to 10 min, essentially shortens the procedure and simplifies it.
(11) Forty-one specimens of mucinous cystadenoma (MCA) of the ovary and 13 specimens of normal uterine endocervix were investigated histochemically using alcian blue pH 2.5-PAS, high iron diamine-alcian blue pH 2.5, galactose oxidase-Schiff reaction (GOS, for detection of gastric surface mucous cell mucins), paradoxical Concanavalin A staining (PCS, for detection of gastric gland cell mucins) and periodic acid-sodium borohydride-potassium hydroxide-PAS (PA-SB-PH-PAS) reaction (for detection of mucins of the large intestine).
(12) Sections were treated with nitrous acid and then stained with Alcian Blue pH 1.0, high iron diamine or Aldehyde Fuchsin for sulphated glycoconjugates.
(13) To enhance the efficiency and specificity of diamine methods in light microscopy, these methods were sensitized by silver enhancement in combination with trichloro(ethylene) platinate (KTP).
(14) Inhibition of MDA production to below control levels using the antioxidant N,N'-diphenyl-phenylene diamine (DPPD) however, had no inhibitory effect on cocaine-induced cytotoxicity in either mouse or rat cells.
(15) From all mammals investigated so far only in rabbits diamine oxidase could not be detected in any tissue except the gut.
(16) The objective of the present investigation was to examine the effect of (2R,5R)-6-heptyne-2,5-diamine (methyl-acetylenicputrescine; MAP), an irreversible inhibitor of ODC, on the induction of alloreactivity in vivo.
(17) During early pregnancy the rise of serum diamine oxidase (DAO) is confined within narrow limits to certain weeks of gestation.
(18) Derivatization of carboxyl groups on the carbon surface with a poly(oxyalkalene)diamine (Jeffamine ED-600), followed by biotinylation of the free amine, allowed the attachment of a fluorescein isothiocyanate (FITC) conjugate of ExtrAvidin.
(19) No changes in plasma diamine oxidase activity were observed in saline-treated animals during intestinal ischemia and following revascularization.
(20) Diamine oxidase was also assayed in spent culture media to assess its spontaneous release by CaCo-2 cells.