What's the difference between diathesis and predisposition?
Diathesis
Definition:
(n.) Bodily condition or constitution, esp. a morbid habit which predisposes to a particular disease, or class of diseases.
Example Sentences:
(1) The post-mortem examination revealed that in sixteen animals there was equally expressed hemorrhagic diathesis, five of which had clinical icterus, five manifested subclinical icterus, and six showed no icterus.
(2) An otherwise healthy woman developed a hemorrhagic diathesis with fluctuating clinical symptoms and laboratory findings, but without thrombocytopenia, over 8 years.
(3) There was a linear correlation between thrombopenia and the presence of hemorrhagic diathesis and low levels of C4 and CH50 components.
(4) He was admitted to hospital with a severe haemorrhagic diathesis which, at first, was thought to be a familial haemorrhagic disease, his mother having died of recurrent hypoprothrombinaemia a few years earlier, the cause of her bleeding trouble never having been established.
(5) The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis.
(6) Total gastrectomy was performed in 8 of the 12 Z-E patients, with abolition of the ulcer diathesis in all.
(7) These functional abnormalities may well be related to posttraumatic hemorrhage as observed in a 33-yr-old man with moderate hemorrhagic diathesis related to injuries since his early adolescence.
(8) A dysfibrinogenemia (fibrinogen Sevilla) was detected in a 64-yr-old woman with no previous history of hemorrhagic diathesis or thrombosis.
(9) Adenosine is a potent inhibitor of the enzyme ATPase and, in this way, contributes to the anemia, the bleeding diathesis and the CNS symptoms of uremia.
(10) Such an approach provides the basis for developing broader, yet more specific, frameworks for investigating diathesis-stress theories of psychopathology in general and of depression in particular.
(11) A clinical classification is proposed, based on severity of the bleeding diathesis and platelet count at presentation.
(12) The main results and problems of research work on this haemorrhagic diathesis are shortly reviewed.
(13) After transfusion of stroma-free haemoglobin preparation, no signs of haemorrhagic diathesis were observed.
(14) Neonatal intracerebral hemorrhage should raise the question of congenital tumor because such a hemorrhage in this age group is rarely the result of trauma, bleeding diathesis, or vascular malformation.
(15) In the severely bleeding patient with hemorrhagic diathesis heparin is contraindicated because it does not normalize coagulability.
(16) By the mid 20th century, however, the apparent decline of the gout in Europe and North America and the breakup of the gouty diathesis in those lands had been more than compensated by their large-scale reappearance in the Maori and in other indigenous inhabitants of the Pacific Basin who, at first sight, appeared to have become one large gouty family.
(17) Based on literature and on the results of this open clinical trial we conclude, that there is no connection between application of the above named group of drugs and the change in parameters of haemostasis function, which might lead to a manifest haemorrhagic diathesis.
(18) Vitamin K deficient hemorrhagic diathesis is well known as a cause of infantile intracranial hemorrhage.
(19) A familial diathesis seems to exist for VD, following a dominant mode of inheritance.
(20) These findings provide further evidence that disseminated intravascular coagulation and enhanced fibrinolysis in the late stages of schistosomiasis may contribute to the haemorrhagic diathesis seen in the liver and spleen.
Predisposition
Definition:
(n.) The act of predisposing, or the state of being predisposed; previous inclination, tendency, or propensity; predilection; -- applied to the mind; as, a predisposition to anger.
(n.) Previous fitness or adaptation to any change, impression, or purpose; susceptibility; -- applied to material things; as, the predisposition of the body to disease.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(3) The reported findings strongly support the predisposition hypothesis.
(4) The characteristic predisposition to neoplasia exists, however, as probably does that to diabetes mellitus.
(5) Our knowledge of the pathogenesis of ordinary baldness is far from complete but a genetic predisposition is necessary and androgen production must be present.
(6) Predisposition to pancreatitis relates to duct size rather than stone size per se.
(7) Of CD patients, 92% (50% DR3 and 42% DR5,7) compared to 18% of the controls carry both DQA1*0501 and DQB1*0201 alleles, so that the combination confers an RR of 52, higher than both the risks of the single alleles (DQA1*0501 RR = 19, DQB1*0201 RR = 30), confirming the primary role of the dimer in determining genetic predisposition to CD both in DR3 and in DR5,7 subjects.
(8) For over two decades, evidence has been accumulating that supports a genetic predisposition to alcoholism and the presence of subgroups among alcoholics.
(9) A thromboembolism is sometimes predictable in individuals if there is migraine, visual disturbance, or certain predispositions seen in pregnancy such as toxemia or hypertension.
(10) Questionnaires assessing symptoms, disability and handicap, predisposition to anxiety, and current anxiety and depression were completed by 127 people attending neuro-otology clinics with a major complaint of vertigo or dysequilibrium.
(11) The functional interaction between prostacyclin and thromboxane was examined in terms of a number of risk factors for coronary heart disease (CHD), such as ageing, atherosclerosis, arterial hypertension, diabetes mellitus, obesity, hypokinesia, smoking, alcoholism, sex differences, and predisposition to the disease.
(12) Because the predisposition locus for multiple endocrine neoplasia type 2A (MEN2A) has been mapped to chromosome 10 by genetic linkage analysis, it has become possible to identify gene carriers by following the transmission of linked genetic markers from affected parents to offspring at risk for MEN2A.
(13) The findings suggest that migraine, major depression and anxiety disorders might share common predispositions.
(14) Microstructural rearrangements and nonhomologous recombination in nondisjunction of chromosomes during cell division are considered parallel with mosaicism as one of possible reasons of genetic predisposition.
(15) There was no correlation between specific HLA antigens and predisposition to develop cytomegalovirus infection.
(16) The certainty of a strong genetic predisposition to malignant melanoma was first established over 35 years ago.
(17) The sampling was balanced with respect to age, gender, and predisposition across the three ordinal exposure categories.
(18) Trait anxiety levels (predisposition to anxiety) and personality profiles were recorded in four novice anaesthetists prior to the start of their training in anaesthesia.
(19) Genetic predisposition to diabetes is characterized by immunodeficiency as evident from inadequate levels of antibodies to infectious or noninfectious antigens and absolute and relative deficiency in spleen lymphocyte subsets and total numbers of spleen cells.
(20) Tumor suppressor genes have been identified by genetic analysis either as loci associated with an inherited predisposition to certain tumors or by mapping studies that demonstrate allelic loss (reduction to homozygosity or loss of heterozygosity) during tumor development.