(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Elusive
Definition:
(a.) Tending to elude; using arts or deception to escape; adroitly escaping or evading; eluding the grasp; fallacious.
Example Sentences:
(1) The successful treatment of the painful neuroma remains an elusive surgical goal.
(2) Diagnostic difficulties were encountered due to the rarity of such infections and elusive identification of the organism with routine laboratory procedures.
(3) Diagnosis with light microscopy can be elusive; electron microscopic and immunohistochemical evaluation are necessary to confirm the pathological condition.
(4) But an agreement looks elusive, and it appears that another election will be held soon.
(5) Effectiveness and safety of other molecules remain elusive.
(6) Thus, the identity of the suppressive factor(s) in cultured I-CB cell supernatants remains elusive.
(7) The quality of family life is as elusive a concept as is quality of life for the individual.
(8) In the United States, early diagnosis and cure of gastric carcinoma remain elusive.
(9) Despite their functional prominence, the structural requirements of fully functional GABAA-receptors are still elusive.
(10) The explanation for this dramatic loss of GSH has been investigated by many laboratories but the solution has been elusive.
(11) While the etiology and pathogenesis of such lesions remain elusive, physicians performing hair transplantations should be aware of this potential sequela.
(12) Les Cafeteras began the second half in similarly determined mode and the elusive Rincón sent a shot dipping fractionally over the bar from distance.
(13) Never before has so much been learned about the molecular biology of a virus in such a short time since its discovery and yet effective strategies for fighting the human immunodeficiency virus that causes AIDS remain elusive.
(14) With her first book, Girl Online, due out in November and an audience estimated to be 26 times that of the circulation of British Vogue, Zoella is a key example of what the advertising world call a “crowdsourced people’s champion” – one who earns hundreds of thousands of pounds a year and is paid by brands such as Unilever to connect with the ever-elusive 18-30 demographic.
(15) We retrospectively reviewed the MR examinations of five patients with surgically proved cervical epidural abscess in order to assist in the diagnosis of this clinically elusive disorder.
(16) Steroid hormone receptors are elusive, labile regulatory proteins which communicate the action of the sex hormones, estrogens and progestins, in target organs such as the breast and uterus.
(17) However, the principles of optimal mAb selection remain elusive, as their efficacy in vivo does not always correlate with their characteristics in vitro.
(18) Bacterial endocarditis is an elusive disease that challenges clinicians' diagnostic capabilities.
(19) The chronic inflammatory diseases in humans have been intensively investigated, however the immune mechanisms underlying diseases such as rheumatoid arthritis (RA), inflammatory bowel disease, and periodontal disease (PD) remain elusive.
(20) Three years later, the proud owner of a PG diploma in housing studies and member of the Chartered Institute of Housing, I was offered the opportunity to complete a further year's study and obtain that elusive degree.