(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Impracticable
Definition:
(a.) Not practicable; incapable of being performed, or accomplished by the means employed, or at command; impossible; as, an impracticable undertaking.
(a.) Not to be overcome, presuaded, or controlled by any reasonable method; unmanageable; intractable; not capable of being easily dealt with; -- used in a general sense, as applied to a person or thing that is difficult to control or get along with.
(a.) Incapable of being used or availed of; as, an impracticable road; an impracticable method.
Example Sentences:
(1) This mode of treatment remains appropriate for cases where antibiotics are ineffective and surgery impracticable.
(2) In cystic hydatid disease, whenever radical surgical procedures are impracticable, albendazole treatment can achieve significant clinical results.
(3) The transplantation may be replaced by implantation of a cardioverter if the former is impracticable or will be performed in future.
(4) The transplantation of organs between species (xenografting) has long been considered impracticable due to the immunological barriers allegedly induced by the antigenic disparity of distantly related species.
(5) One wonders what his defense minister Ehud Barak and the former Mossad chief Meir Dagan, and other Israeli leaders who disagree with him in his analysis of the urgency of the Iranian nuclear threat, think of his public commitment to such a fraught – that understates it – such a perilous and perhaps impracticable military operation.
(6) It is impracticable to reduce cadmium concentrations in sludge below certain levels.
(7) Simple insertion, rapid stabilization and reaction time less than 60 s allow use in the initial stages of cardiopulmonary resuscitation (CPR) where invasive monitoring is often impracticable.
(8) Sixty-three per cent regarded the boiling and filtration of portions of their domestic water as an additional burden, cumbersome and impracticable.
(9) When the primary site makes resection impracticable, the response to irradiation and chemotherapy is encouraging.
(10) Presenting the clinical data and regarding percutaneous paracentetic nephrostomy as an optimum technique for the clinical practice, the authors concluded UCS to be impracticable.
(11) Owing to the high incidence of side effects, treatment with more than 75 mg terodiline chloride per day is impracticable.
(12) Nevertheless, they are impracticable to perform and unsuitable for routine use in many individuals.
(13) In addition, volumetric determination of tumour size by means of region-of-interest technique proved to be rather impracticable in clinical routine compared to bidimensional measurement.
(14) Influenza vaccine is impracticable in most developing countries.
(15) This conventional system is impracticable for some laboratories that process enormous numbers of blood cultures and for these laboratories the infrared Bactec system is recommended.
(16) It is suggested that jejunal interposition should be kept for cases in which the particular shortness of the gastric stump makes simple re-insertion of the duodenum into the stomach impracticable.
(17) Derivatization with diazomethane instead of methanolic HCl turned out to be impracticable.
(18) Despite indirect evidence in support of this claim, the impracticability of monitoring oestrogen and progesterone levels in large numbers of women for prolonged periods of time has meant that no direct demonstration of the effect has been made.
(19) Similarly, a variety of other coating and attachment devices have proved to be unsatisfactory or impracticable for large scale investigations.
(20) The usual methods of choice, selective abdominal angiography and colonoscopy, may be impracticable or fail.