(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Indistinct
Definition:
(a.) Not distinct or distinguishable; not separate in such a manner as to be perceptible by itself; as, the indistinct parts of a substance.
(a.) Obscure to the mind or senses; not clear; not definite; confused; imperfect; faint; as, indistinct vision; an indistinct sound; an indistinct idea or recollection.
Example Sentences:
(1) The main lesions of the tegument included indistinct of the matrix, vacuolization and peeling, while vacuolization of perinuclear cytoplasma in tegumental cells, focus lysis in muscle bundles, and destruction in collection ducts and flame cells were also seen.
(2) Importantly, although not pathognomonic, the high-resolution CT finding of centrilobular, peribronchiolar, indistinct nodules should suggest the diagnosis of chronic hypersensitivity pneumonitis.
(3) Radiologically it appeared as an osteolytic lesion with marginally indistinct borders in the epimetaphyseal region of the proximal tibia.
(4) The infantile fibrosarcoma affected children below the age of seven years in this series and was characterized by proliferation of immature fibroblasts forming indistinct bundles, frequently exhibiting areas of an angiosarcoma-like pattern and cavernous blood vessels.
(5) Indistinctness of risk factors, especially workplace factors, is the principal reason for the poor results of intervention epidemiology: very few primary prevention programs and no educational programs ("low back school") have been shown to be really effective.
(6) It is proposed that all indistinct hyponatremias be thoroughly analysed and that urinary ADH be tentatively considered as a tumor marker for colon carcinoma.
(7) In an indistinct room, with a blurred painting in the background, the US-educated politician pledged to continue street actions alongside the Venezuelan people, while acknowledging he faces the risk of being jailed.
(8) were found and they had no embryos and indistinct opercula.
(9) Collagen occurs in the extracellular matrix of the bovine vitreous as fibers which have a fairly uniform diameter of approximately 195 A and exhibit an indistinct axial periodicity.
(10) All seven neoplasms were histologically similar, being composed of large cells with large nuclei, a moderate amount of cytoplasm, and indistinct cell borders.
(11) While this is all well and good, a counter-narrative could easily be presented: "I watched in quiet horror as the ultrasound flickered, showing the still-indistinct at 14-week mass focusing in and out on the screen.
(12) This may lead t o prominence and indistinct borders of the optic disc.
(13) The sonograms showed a small peripheral malformation that was indistinct on selective renal angiography.
(14) The above results suggests that in high myopia the optic disc was tilted and the rim-cup border was indistinct and there are some problems in the estimation of the morphometric parameters.
(15) Bronchial brushing smears contained clusters of cells exhibiting abundant diffusely granular cytoplasm with indistinct borders.
(16) Records of responses obtained from the DOC-treated sugar receptor showed long response latencies that gradually became indistinct with recovery.
(17) Follicles also were classified as clear or cloudy; cloudy was associated with flocculent material in the follicular fluid or with an indistinct follicular wall.
(18) Probably as a consequence of depressed structural-protein synthesis, very few progeny virions are released and the mutant makes tiny or indistinct plaques even after prolonged incubation.
(19) The usually indistinctive and unspecified liquor syndrome requires a subtly differentiated diagnostic distinguishing between vascular brain stem syndromes and brain stem gliomas.
(20) In cross-sections of the SOL muscle one group of fibres showed indistinct M-bridges, whereas distinct M-bridges were seen in the other fibres and in all observed EDL muscle fibres.